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Sequential change in quality of life for patients with incident clinical fractures: a prospective study

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Abstract

Summary

Health-related quality of life in elderly women with sustained incident fractures was assessed prospectively for 1 year, using the EuroQol standard. Loss of QOL was more severe in patients after hip or vertebral fractures than those with wrist fracture. QOL was not completely restored in patients suffering from hip fracture.

Introduction

Osteoporosis-related fractures decrease mobility, social interaction, and emotional well-being. All of these characteristics determine health-related quality of life (HR-QOL). In this study, we assessed HR-QOL in elderly women following incident clinical fractures.

Methods

Thirty-seven patients with hip fractures (mean age 76.1 years), 35 with vertebral fractures (mean age 72.6 years), and 50 with wrist fractures (mean age 68.6 years) were enrolled. HR-QOL was prospectively measured using EuroQol (EQ-5D) before the fracture, 2 weeks, 3 months, 6 months, and 1 year after the fracture.

Results

During the observation period, reduction of EQ-5D values was greatest in the hip fracture group. In the wrist fracture group, EQ-5D values at 6 months after the fracture showed recovery; however, in the hip and vertebral fracture groups, recovery was significantly lower than before the fracture. One year after the fracture, EQ-5D values were not significantly different from prefracture values in the vertebral and wrist fracture groups, but remained significantly lower in the hip fracture group.

Conclusions

Loss of QOL was more severe in patients after hip or vertebral fractures than in patients with wrist fracture. HR-QOL was not completely restored in patients suffering from hip fracture.

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Acknowledgments

The authors thank Masatoshi Nakashima, M.D., Masaaki Shimizu, M.D., Kimiko Tsuda, M.D., and Noboru Yamagata, M.D., for their help and support.

Conflicts of interest

None.

Author information

Authors and Affiliations

  1. Rehabilitation Division, Tottori University Hospital, Yonago, Japan

    H. Hagino

  2. Department of Fundamental Nursing, School of Health Science, Faculty of Medicine, Tottori University, Yonago, Japan

    H. Hagino & M. Oeki

  3. Department of Orthopedic Surgery, University of Occupational and Environmental Health, Fukuoka, Japan

    T. Nakamura

  4. Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan

    S. Fujiwara

  5. Department of Orthopedic Surgery, Faculty of Medicine, Tottori University, Yonago, Japan

    T. Okano & R. Teshima

  6. School of Health Science, Tottori University, Yonago, Tottori, 683-8503, Japan

    H. Hagino

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  1. H. Hagino
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  2. T. Nakamura
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  3. S. Fujiwara
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  4. M. Oeki
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  5. T. Okano
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  6. R. Teshima
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Correspondence to H. Hagino.

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Hagino, H., Nakamura, T., Fujiwara, S. et al. Sequential change in quality of life for patients with incident clinical fractures: a prospective study. Osteoporos Int 20, 695–702 (2009). https://doi.org/10.1007/s00198-008-0761-5

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  • DOI: https://doi.org/10.1007/s00198-008-0761-5

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