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The emerging power of molecular diagnostics: towards improved management of life-threatening infection

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References

  1. Pittet D, Li N, Woolson RF, Wenzel RP (1994) Nosocomial bloodstream infection in critically ill patients: excess length of stay, extra costs, and attributable mortality. JAMA 271:1598–1601

    Article  CAS  PubMed  Google Scholar 

  2. Byl B, Clevenbergh P, Jacobs F, Struelens MJ, Zech F, Kentos A, Thys JP (1999) Impact of infectious diseases specialists and microbiological data on the appropriateness of antimicrobial therapy for bacteremia. Clin Infect Dis 29: 60–66

    Article  CAS  PubMed  Google Scholar 

  3. Fredericks DN, Relman DA (1999) Application of polymerase-chain reaction to the diagnosis of infectious diseases. Clin Infect Dis 29: 475–488

    Article  Google Scholar 

  4. Rantakokko-Jalava K, Nikkari S, Jalava J, et al (2000) Direct amplification of rRNA genes in diagnosis of bacterial infections. J Clin Microbiol 38: 32–39

    CAS  PubMed Central  PubMed  Google Scholar 

  5. Anthony RM, Brown TJ, French GL (2000) Rapid diagnosis of bacteremia by universal amplification of 23S ribosomal DNA followed by hybridization to an oligonucleotide array. J Clin Microbiol 38: 781-788

    Google Scholar 

  6. Turenne CY, Witwicki E, Hoban DJ, Karlowsky JA, Kabani AM (2000) Rapid identification of bacteria from positive blood cultures by fluorescence-based PCR-single-strand conformation polymorphism analysis of the 16S rRNA gene. J Clin Microbiol 38: 513–520

    CAS  PubMed Central  PubMed  Google Scholar 

  7. Sleight J, Cursons R, La Pine M (2001) Detection of bacteraemia in critically ill patients using 16S rDNA polymerase chain reaction and DNA sequencing. Intensive Care Med 27:1269–1273

    Article  Google Scholar 

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Correspondence to Marc J. Struelens.

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Struelens, M.J., de Mendonça, R. The emerging power of molecular diagnostics: towards improved management of life-threatening infection. Intensive Care Med 27, 1696–1698 (2001). https://doi.org/10.1007/s001340101102

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  • DOI: https://doi.org/10.1007/s001340101102

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