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The use of low-dose IV haloperidol is not associated with QTc prolongation: post hoc analysis of a randomized, placebo-controlled trial

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References

  1. Swan JT, Fitousis K, Hall JB, Todd SR, Turner KL (2012) Antipsychotic use and diagnosis of delirium in the intensive care unit. Crit Care 16:R84

    Article  PubMed  PubMed Central  Google Scholar 

  2. Drew BJ, Ackerman MJ, Funk M, American Heart Association Acute Cardiac Care Committee of the Council on Clinical C, Council on Cardiovascular N, American College of Cardiology F et al (2010) Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation. J Am Coll Cardiol 55:934–947

    Article  PubMed  PubMed Central  Google Scholar 

  3. Sharma ND, Rosman HS, Padhi ID, Tisdale JE (1998) Torsades de pointes associated with intravenous haloperidol in critically ill patients. Am J Cardiol 81:238–240

    Article  CAS  PubMed  Google Scholar 

  4. Tisdale JE, Rasty S, Padhi ID, Sharma ND, Rosman H (2001) The effect of intravenous haloperidol on QT interval dispersion in critically ill patients: comparison with QT interval prolongation for assessment of risk of torsades de pointes. J Clin Pharmacol 41:1310–1318

    Article  CAS  PubMed  Google Scholar 

  5. Al-Qadheeb NS, Skrobik Y, Schumaker G, Pacheco MN, Roberts RJ, Ruthazer RR, Devlin JW (2016) Preventing ICU subsyndromal delirium conversion to delirium with low-dose IV haloperidol: a double-blind, placebo-controlled pilot study. Crit Care Med 44:583–591

    Article  CAS  PubMed  Google Scholar 

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Correspondence to John W. Devlin.

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Duprey, M.S., Al-Qadheeb, N., Roberts, R. et al. The use of low-dose IV haloperidol is not associated with QTc prolongation: post hoc analysis of a randomized, placebo-controlled trial. Intensive Care Med 42, 1818–1819 (2016). https://doi.org/10.1007/s00134-016-4512-3

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