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Diffusionsgewichtete Magnetresonanztomographie des Abdomens

Diffusion-weighted magnetic resonance imaging of the abdomen

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Zusammenfassung

Die diffusionsgewichtete (DW-)MRT ermöglicht die Erfassung qualitativer und quantitativer Informationen bzgl. der Gewebezellularität und Membranintegrität. Die DW-MRT ist insbesondere bei Patienten mit einer Allergie gegen gadoliniumhaltige Kontrastmittel oder eingeschränkter Nierenfunktion attraktiv, da ihr Einsatz nicht mit Strahlenexposition oder Kontrastmittelgabe verbunden ist. Durch technische Weiterentwicklungen ist die robuste Anwendung der DW-MRI in der Bildgebung des Abdomens seit einiger Zeit möglich geworden. In der Leberdiagnostik lassen sich Zusatzinformationen zur Detektion und Charakterisierung von Leberläsionen gewinnen, aber auch Therapieerfolge dokumentieren und frühe chronische Leberveränderungen visualisieren. Neben ihrer Rolle bei hepatologischen und onkologischen Fragestellungen erscheint der Einsatz der DW-MRT zudem bei entzündlichen Fragestellungen wie dem Morbus Crohn sehr viel versprechend.

Abstract

Diffusion-weighted magnetic resonance imaging (DW-MRI) provides qualitative and quantitative information of tissue cellularity and the integrity of cellular membranes. Since DW-MRI can be performed without ionizing radiation exposure and contrast media application, DW-MRI is a particularly attractive tool for patients with allergies for gadolinium-based contrast agents or renal failure. Recent technical developments have made DW-MRI a robust and feasible technique for abdominal imaging. DW-MRI provides information on the detection and characterization of focal liver lesions and can also visualize treatment effects and early changes in chronic liver disease. In addition DW-MRI is a promising tool for the detection of inflammatory changes in patients with Crohn’s disease.

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Literatur

  1. Bammer R (2003) Basic principles of diffusion-weighted imaging. Eur J Radiol 45:169–184

    Article  PubMed  Google Scholar 

  2. Bruegel M, Gaa J, Waldt S et al (2008) Diagnosis of hepatic metastasis: comparison of respiration-triggered diffusion-weighted echo-planar MRI and five T2-weighted turbo spin-echo sequences. AJR Am J Roentgenol 191:1421–1429

    Article  PubMed  Google Scholar 

  3. Dietrich O (2008) Diffusion-weighted imaging and diffusion tensor imaging. In: Reiser MF, Semmler W, Hricak H (eds) Magnetic resonance tomography. Springer, Berlin Heidelberg New York, S 130–152

  4. Dietrich O, Biffar A, Baur-Melnyk A et al (2010) Technical aspects of MR diffusion imaging of the body. Eur Radiol (in press)

  5. Fiebach JB, Schellinger PD (2003) Modern magnetic resonance techniques in stroke. Radiologe 43:251–263

    Article  PubMed  CAS  Google Scholar 

  6. Huisman TA, Hawighorst H, Benoit CH et al (2001) Diffusion-weighted MRI: ischemic and traumatic injuries of the central nervous system. Radiologe 41:1038–1047

    Article  PubMed  CAS  Google Scholar 

  7. Hussain SM, De Becker J, Hop WC et al (2005) Can a single-shot black-blood T2-weighted spin-echo echo-planar imaging sequence with sensitivity encoding replace the respiratory-triggered turbo spin-echo sequence for the liver. An optimization and feasibility study. J Magn Reson Imaging 21:219–229

    Article  PubMed  Google Scholar 

  8. Ichikawa T, Haradome H, Hachiya J et al (1998) Diffusion-weighted MR imaging with a single-shot echo-planar sequence: detection and characterization of focal hepatic lesions. AJR Am J Roentgenol 170:397–402

    PubMed  CAS  Google Scholar 

  9. Jaermann T, Pruessmann KP, Valavanis A (2006) Influence of SENSE on image properties in high-resolution single-shot echo-planar DTI. Magn Reson Med 55:335–342

    Article  PubMed  CAS  Google Scholar 

  10. Kamel IR, Liapi E, Reyes DK et al (2009) Unresectable hepatocellular carcinoma: serial early vascular and cellular chances after transarterial chemoembolization as detected with MR imaging. Radiology 466–473

  11. Kim T, Murakami T, Takahashi S et al (1999) Diffusion-weighted single-shot echoplanar MR imaging for liver disease. AJR Am J Roentgenol 173:393–398

    PubMed  CAS  Google Scholar 

  12. Kiryu S, Dodanuki K, Takao H et al (2009) Free-breathing diffusion-weighted imaging for the assessment of inflammatory activity in Crohn’s disease. J Magn Reson Imaging 29:880–886

    Article  PubMed  Google Scholar 

  13. Koh DM, Collins DJ (2007) Diffusion-weighted MRI in the body: applications and challenges in oncology. AJR Am J Roentgenol 188:1622–1635

    Article  PubMed  Google Scholar 

  14. Koh DM, Brown G, Riddell AM et al (2008) Detection of colorectal hepatic metastases using MnDPDP MR imaging and diffusion-weighted imaging (DWI) alone and in combination. Eur Radiol 18:903–910

    Article  PubMed  CAS  Google Scholar 

  15. Lewin M, Poujol-Robert A, Boelle PY et al (2007) Diffusion-weighted magnetic resonance imaging for the assessment of fibrosis in chronic hepatitis C. Hepatology 46:658–665

    Article  PubMed  CAS  Google Scholar 

  16. Naganawa S, Sato C, Nakamura T et al (2005) Diffusion-weighted images of the liver: comparison of tumor detection before and after contrast enhancement with superparamagnetic iron oxide. J Magn Reson Imaging 21:836–840

    Article  PubMed  Google Scholar 

  17. Naganawa S, Kawai H, Fukatsu H (2005) Diffusion-weighted imaging of the liver: technical challenges and prospects for the future. Magn Reson Med Sci 31:175–186

    Article  Google Scholar 

  18. Oto A, Zhu F, Kulkarni K et al (2009) Evaluation of diffusion-weighted MR imaging for detection of bowel inflammation in patients with Crohn’s disease. Acad Radiol 16:597–603

    Article  PubMed  Google Scholar 

  19. Parikh T, Drew SJ, Lee VS et al (2008) Focal liver lesion detection and characterization with diffusion-weighted MR imaging: comparison with standard breath-hold-T2-weighted imaging. Radiology 246:812–822

    Article  PubMed  Google Scholar 

  20. Patterson DM, Padhani AR, Collins DJ (2008) Technology insight: water-diffusion MRI-a potential new biomarker of response to cancer therapy. Nat Clin Pract Oncol 5:220–233

    Article  PubMed  Google Scholar 

  21. Persigehl T, Heindl W, Bremer C (2008) Modern magnetic resonance procedures for assessing tumor response. Radiologe 48:863–870

    Article  PubMed  CAS  Google Scholar 

  22. Qayyum A (2009) Diffusion-weighted imaging in the abdomen and pelvis: concepts and applications. Radiographics 29:1797–1810

    Article  PubMed  Google Scholar 

  23. Riddell RH (2009) Pathology of idiopathic inflammatory bowel disease. In: Kirsner JB (ed) Inflammatory bowel disease. Saunders, Philadelphia, pp 427–452

  24. Sharma U, Danishad KK, Seenu V et al (2009) Longitudinal study of the assessment by MRI and diffusion-weighted imaging of tumor response in patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy. NMR Biomed 22:104–113

    Article  PubMed  Google Scholar 

  25. Takahara T, Imai Y, Yamashita T et al (2004) Diffusion-weighted whole body imaging with background body signal suppression (DWIBS): technical improvement using free breathing, STIR and high resolution 3D display. Radiat Med 22:275–282

    PubMed  Google Scholar 

  26. Taouli B, Sandberg A, Stemmer A et al (2009) Diffusion-weighted imaging of the liver: comparison of navigator triggered and breath-hold acquisitions. J Magn Reson Imaging 30:561–568

    Article  PubMed  Google Scholar 

  27. Taouli B, Koh DM (2010) Diffusion-weighted MR imaging of the liver. Radiology 254:47–66

    Article  PubMed  Google Scholar 

  28. Thoeny HC, De Keyzer F, Vandecaveye V et al (2005) Effect of vascular targeting agent in rat tumor model: dynamic contrast-enhanced versus diffusion-weighted MR-imaging. Radiology 237:492–499

    Article  PubMed  Google Scholar 

  29. Thoeny HC, De Keyzer F (2007) Extracranial applications of diffusion-weighted magnetic resonance imaging. Eur Radiol 17:1385–1393

    Article  PubMed  Google Scholar 

  30. Vossen JA, Bujis M, Liapi E et al (2008) Receiver operating characteristic analysis of diffusion-weighted magnetic resonance imaging in differentiating hepatic hemangioma from other hypervascular liver lesions. J Comput Assist Tomogr 32:750–756

    Article  PubMed  Google Scholar 

  31. Zech CJ, Schoenberg SO, Herrmann KA et al (2004) Modern visualization of the liver with MRT. Current trends and future perspectives. Radiologe 44:1160–1169

    Article  PubMed  CAS  Google Scholar 

  32. Zech CJ, Herrmann KA, Dietrich O et al (2008) Black-blood diffusion-weighted EPI acquisition of the liver with parallel imaging: comparison with a standard T2-weighted sequence for detection of focal liver lesions. Invest Radiol 43:261–266

    Article  PubMed  Google Scholar 

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  1. Institut für Klinische Radiologie, Klinikum der Ludwig-Maximilians-Universität München, Campus Grosshadern, Marchioninistr. 15, 81377, München, Deutschland

    C. Schmid-Tannwald, M.F. Reiser &  C.J. Zech

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  1. C. Schmid-Tannwald
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  2. M.F. Reiser
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  3. C.J. Zech
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Correspondence to C.J. Zech.

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Schmid-Tannwald, C., Reiser, M. & Zech, C. Diffusionsgewichtete Magnetresonanztomographie des Abdomens. Radiologe 51, 195–204 (2011). https://doi.org/10.1007/s00117-010-2060-3

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