Zusammenfassung
Ein 33-jähriger Mann wurde wegen heftigen Erbrechens stationär aufgenommen. Bereits seit 11 Jahren litt er unter wiederkehrenden stereotypen Erbrechensepisoden von 3–4 Tagen Dauer. Die Erbrechensepisoden traten 10- bis 15-mal pro Jahr auf. Zudem klagten auch der Bruder und die Mutter des Patienten über ähnliche Beschwerden. Ursächlich zeigte sich ein (familiäres) zyklisches Erbrechenssyndrom. Unter antiemetischer und sedierender Therapie konnte die akute Erbrechensepisode unterbrochen werden. Zudem wurde eine Prophylaxe mit Amitriptylin eingeleitet. Daraufhin war der Patient über 3 1/2 Jahre beschwerdefrei.
Abstract
A 33-year-old man was admitted because of severe vomiting. For the last 11 years, he had suffered recurrent stereotypical episodes of vomiting lasting 3–4 days. The episodes of vomiting occurred 10–15 times a year. Moreover his brother and his mother had similar symptoms. Thus, (familial) cyclic vomiting syndrome was diagnosed. With the help of antiemetic and sedative drugs, the acute vomiting episode was stopped. Prophylactic therapy with amitriptyline was started, which led to a symptom-free period of 3.5 years without a new episode of vomiting.
Literatur
Abell TL, Adams KA, Boles RG et al (2008) Cyclic vomiting syndrome in adults. Neurogastroenterol Motil 20:269–284
Boles RG, Lovett-Barr MR, Preston A et al (2010) Treatment of cyclic vomiting syndrome with coenzyme Q10 and amitriptyline, a retrospective study. BMC Neurol 10:1–5
Boles RG, Williams JC (1999) Mitochondrial disease and cyclic vomiting syndrome. Dig Dis Sci 44 (Suppl):103–107
Chelimsky G, Madan S, Alshekhlee A et al (2009) A comparison of dysautonomias comorbid with cyclic vomiting syndrome and with migraine. Gastroenterol Res Pract 1–6: 701019 [Epub ahead of print]
Chow S, Goldman RD (2007) Treating children’s cyclic vomiting. Can Fam Physician 53:417–419
Duckett A, Pride P (2010) Cyclic vomiting syndrome in an adult patient. J Hosp Med 5:251–252
Fleisher DR, Gornowicz B, Adams K et al (2005) Cyclic vomiting syndrome in 41 adults: the illness, the patients, and problems of management. BMC Med 3:1–12
Fleisher DR, Matar M (1993) The cyclic vomiting syndrome: a report of 71 cases and literature review. J Pediatr Gastroenterol Nutr 17:361–369
Forbes D, Fairbrother S (2008) Cyclic nausea and vomiting in childhood. Aust Fam Physician 37:33–36
Haan J, Kors EE, Ferrari MD (2002) Familial cyclic vomiting syndrome. Cephalgia 22:552–554
Haghighat M, Rafie SM, Dehghani SM et al (2007) Cyclic vomiting syndrome in children: experience with 181 cases from southern Iran. World J Gastroenterol 23:1833–1836
Hejazi RA, Reddymasu SC, Namin F et al (2010) Efficacy of tricyclic antidepressant therapy in adults with cyclic vomiting syndrome: a two-year follow-up study. J Clin Gastroenterol 44:18–21
Li BU, Lefevre F, Chelimsky GG et al (2008) North american society for pediatric gastroenterology, hepatology, and nutrition consensus statement on diagnosis and management of cyclic vomiting syndrome. J Pediatr Gastroenterol Nutr 47:379–393
McOmber MA, Shulman RJ (2008) Pediatric functional gastrointestinal disorders. Nutr Clin Pract 23:268–278
Namin F, Patel J, Lin Z et al (2007) Clinical, psychiatric and manometric profile of cyclic vomiting syndrome in adults and response to tricyclic therapy. Neurogastroenterol Motil 19:196–202
Pareek N, Fleisher DR, Abell T (2007) Cyclic vomiting syndrome: What a gastroenterologist needs to know. Am J Gastroenterol 102:2832–2840
Talley NJ (2007) Functional nausea and vomiting. Aust Fam Physician 35:694–697
Venkatesan T, Tarbell S, Adams K et al (2010) A survey of emergency department use in patients with cyclic vomiting syndrome. BMC Emerg Med 10:1–5
Yang HR (2010) Recent concepts on cyclic vomiting syndrome in children. J Neurogastroenterol Motil 16:139–147
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Keller, K., Beule, J. & Dippold, W. 33-jähriger Patient mit stereotypen Erbrechensepisoden seit 11 Jahren. Internist 53, 345–350 (2012). https://doi.org/10.1007/s00108-011-2962-9
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DOI: https://doi.org/10.1007/s00108-011-2962-9
Schlüsselwörter
- Zyklisches Erbrechenssyndrom
- Familiäres Erbrechensyndrom
- Rezidivierendes Erbrechen
- Antiemetika
- Amitriptylin