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Anästhesie und Analgesie in der Stillperiode

Kriterien der Medikamentenauswahl

Anesthesia and analgesia in the lactation period

Criteria for drug selection

  • Klinische Pharmakologie
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Zusammenfassung

Valide Informationen aus größeren klinischen Studien über den sicheren Einsatz von Anästhetika und Analgetika während der Stillzeit sind so gut wie nicht vorhanden und beschränken sich oft auf Fallberichte oder Untersuchungen an kleinen Kollektiven. Angaben der Herstellerfirmen über die Verwendung der Medikamente sind aus haftungsrechtlichen Gründen restriktiv und häufig mit Gegenanzeige oder Kontraindikation für die Stillzeit versehen. Trotz fehlender Zulassung müssen diese Medikamente gleichwohl täglich bei stillenden Müttern eingesetzt werden. Der vorliegende Beitrag vermittelt einen Überblick darüber, welche Erkenntnisse und klinische Erfahrungen es im Hinblick auf die Pharmakotherapie bei stillenden Müttern, insbesondere bezüglich der im Rahmen einer Anästhesie verabreichten Substanzen, gibt.

Abstract

There is no sound information concerning the safe and correct use of analgesics and anesthetics during the lactation period based on studies with a large sample size. Available information is limited to case studies and small sample observations. As a result, information given by the drug manufacturers about the use of drugs during the lactation period is often restrictive or contains contraindications for the lactation period. Although some drugs are not officially licensed for use during lactation they need to be administered in daily (off-label) use. This review gives an overview about the recent knowledge and clinical experience concerning the perioperative use of anesthetics and analgesics during breast feeding.

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Einhaltung der ethischen Richtlinien

Interessenkonflikt. C. Nassen, C. Schaefer, J. Wirbelauer, A. Hönig und P. Kranke geben an, dass kein Interessenkonflikt besteht. Der Beitrag enthält keine Studien an Menschen oder Tieren.

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Correspondence to P. Kranke.

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Nassen, C., Schaefer, C., Wirbelauer, J. et al. Anästhesie und Analgesie in der Stillperiode. Anaesthesist 63, 415–421 (2014). https://doi.org/10.1007/s00101-014-2311-1

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  • DOI: https://doi.org/10.1007/s00101-014-2311-1

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