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An Addition to Geographic Hematology: Chronic Myeloproliferative Diseases Are Infrequent in Mexican Mestizos

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Abstract

Background. The chronic myeloproliferative diseases (CMPDs) include chronic myelogenous leukemia (CML), primary (essential) thrombocythemia (PT), agnogenic myeloid metaplasia (AMM), and polycythemia vera (PV). Certain hematological malignancies have a different prevalence in our country than in countries with Caucasian populations. Data indicate that the prevalence of CML in our country is similar to that found in Caucasians; however, the prevalence of the other CMPDs has not been studied.

Methods. In a total of 8069 individuals studied between June 1983 and March 2001 in the Centro de Hematologia y Medicina Interna de Puebla, we assessed the prevalence of CML, PT, AMM, and PV. Some of the clinical features of these individuals were also assessed.

Results and Conclusions. Forty-nine patients with CML, 14 with PT, 7 with AMM, and 3 with PV were identified. The clinical presentations of these CMPDs were not different from those described in Caucasians.

Conclusions.We found that CML was more than 3 times more frequent than PT, that both PV and AMM were exceptional, and that PT, AMM, and PV were significantly less frequent in Mexican than in Caucasian populations (P < .01).Int J Hematol. 2002;75:499–502.

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Author notes

  1. Guillermo J. Ruiz-Argüelles

    Present address: Centro de Hematología y Medicina Interna de Puebla, 8B Sur 3710, 72530, Puebla, PUE, Mexico

Authors and Affiliations

  1. Centro de Hematología y Medicina Interna de Puebla, Universidad La Salle, México City, México

    Guillermo J. Ruiz-Argüelles, Briceida López-Martínez & Eduardo Lobato-Mendizábal

  2. Laboratorios Clínicos de Puebla, Universidad La Salle, México City, México

    Guillermo J. Ruiz-Argüelles & Briceida López-Martínez

  3. Facultad Mexicana de Medicina, Universidad La Salle, México City, México

    Guillermo J. Ruiz-Delgado

Authors
  1. Guillermo J. Ruiz-Argüelles
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  2. Briceida López-Martínez
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  3. Eduardo Lobato-Mendizábal
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  4. Guillermo J. Ruiz-Delgado
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Correspondence to Guillermo J. Ruiz-Argüelles.

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Ruiz-Argüelles, G.J., López-Martínez, B., Lobato-Mendizábal, E. et al. An Addition to Geographic Hematology: Chronic Myeloproliferative Diseases Are Infrequent in Mexican Mestizos. Int J Hematol 75, 499–502 (2002). https://doi.org/10.1007/BF02982113

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  • DOI: https://doi.org/10.1007/BF02982113

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