Conclusion
ISE are not suitable for the measurement of ionized calcium under clinical conditions when anions like acetate, lactate or malate are present in concentrations of about 5–10 mmol/l.
References
Cooper DJ, Walley KR, Dodek PM, Rosenberg F, Russel JA (1992) Plasma ionized calcium and blood lactate concentrations are inversely associated in human lactic acidosis. Intensive Care Med 18:286–289
Zander R (1992) Meßfehler bei der Bestimmung von Elektrolytkonzentrationen mit ionenselektiven Elektroden (ISE) bei Anwesenheit von anorganischen und metabolisierbaren. Anionen. Infusionstherapie 19:221–225
National Committee for Clinical Laboratory Standards (1982) 2:10
References
Zander R (1992) Meßfehler bei der Bestimmung von Elektrolytkonzentrationen mit ionen-selektiven Elektroden (ISE) bei Anwesenheit von anorganischen und metabolisierbaren Anionen. Infusionstherapie 19:221–225
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Cooper DJ, Walley KR, Dodek PM, Rosenberg F, Russell JA (1992) Plasma ionised calcium and blood lactate concentrations are inversely associated in human lactic acidosis. Intensive Care Med 18:286–289
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Zander, R., Cooper, D.J. Association between plasma ionized calcium and lactate concentration. Intensive Care Med 19, 362–363 (1993). https://doi.org/10.1007/BF01694716
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DOI: https://doi.org/10.1007/BF01694716