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The Influence of Physical Activity on the Incidence of Site-Specific Cancers in College Alumni

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 322))

Abstract

The past dozen years have seen wide acceptance of epidemiologic evidence that adequate physical activity promotes physical fitness and counters tendencies toward development of coronary heart disease, a chief cause of early debilitation and premature death. But the evidence that physical activity influences cancer incidence is less clear, perhaps because cancer is a variety of diseases differing in underlying cause, age of onset, organ of involvement, induction period, and clinical course. Since exercise is a natural function of the body, its health benefits are thought to be achieved through its effects on all body systems, and accordingly it deserves serious study in relation to any effect it may have on prevention or delay in cancer occurrence.

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References

  1. R.S. Paffenbarger, Jr., P.A. Wolf, J. Notkin, and M.C. Thorne, Chronic disease in former college students: I. Early precursors of fatal coronary heart disease, Am J Epidemiol. 83: 314 (1966).

    PubMed  Google Scholar 

  2. R.S. Paffenbarger, Jr., J. Notkin, D.E. Krueger, P.A. Wolf, M.C. Thorne, E.J. LeBauer, and J.L. Williams, Chronic disease in former college students: II. Methods of study and observations on mortality from coronary heart disease, Am J Public Health. 56: 962 (1966).

    Article  Google Scholar 

  3. A.S. Whittemore, R.S. Paffenbarger, Jr., K. Anderson, and J. Lee, Chronic disease in former college students: XXVII. Early precursors of site-specific cancers in college men and women, J Natl Cancer Inst. 74: 43 (1985).

    PubMed  CAS  Google Scholar 

  4. R.S. Paffenbarger, Jr., R.T. Hyde, and A.L. Wing, Physical activity and incidence of cancer in diverse populations: A preliminary report, Am J Clin Nutr. 45: 312 (1987).

    PubMed  Google Scholar 

  5. R.E. Frisch, G. Wyshak, N.L. Albright, T.E. Albright, I. Schiff, K.P. Jones, J. Witschi, E. Shiang, E. Koff, and M. Marguglio, Lower prevalence of breast cancer and cancers of the reproductive system among former college athletes compared to non-athletes, Br J Cancer. 52: 885 (1985).

    Article  PubMed  CAS  Google Scholar 

  6. I.-M. Lee, R.S. Paffenbarger, Jr., and C.-c. Hsieh, Chronic disease in former college students: XLIV. Physical activity and risk of colorectal cancer among college alumni, J Natl Cancer Inst. 83: 1324 (1991).

    Article  PubMed  CAS  Google Scholar 

  7. I.-M. Lee, R.S. Paffenbarger, Jr., and C.-c. Hsieh, Chronic disease in former college students: XLVI. Physical activity and risk of prostatic cancer among college alumni, Am J Epidemiol. 135: 169 (1992).

    PubMed  CAS  Google Scholar 

  8. R.S. Paffenbarger, Jr., R.T. Hyde, A.L. Wing, and C.H. Steinmetz, Chronic disease in former college students: XXV. A natural history of athleticism and cardiovascular health, J Amer Med Assoc. 252: 491 (1984).

    Article  Google Scholar 

  9. R.S. Paffenbarger, Jr., R.T. Hyde, A.L. Wing, and C.-c. Hsieh, Chronic disease in former college students: XXX. Physical activity, all-cause mortality, and longevity of college alumni, N Engl J Med. 314:605 (1986); 315: 399 (1986).

    Google Scholar 

  10. C. Bouchard, R.J. Shephard, T. Stephens, J.R. Sutton, and B.D. McPherson, (eds), “Exercise, Fitness, and Health,” Human Kinetics Books, Champaign, (1990).

    Google Scholar 

  11. C.J. Caspersen, B.P.M. Bloemberg, W.H.M. Saris, R.K. Merritt, and D. Kromhout, The prevalence of selected physical activities and their relation with coronary heart disease risk factors in elderly men: the Zutphen study, 1985, Am J Epidemiol. 133: 1078 (1991).

    PubMed  CAS  Google Scholar 

  12. B.E. Ainsworth, D.R. Jacobs, Jr., and A.S. Leon, Compendium of physical activities: classification of energy costs of human physical activities, Med Sci Sports Exerc. 1992 (In press).

    Google Scholar 

  13. D.H. Garabrant, J.M. Peters, T.M. Mack, and L. Bernstein, Job activity and colon cancer risk, Am J Epidemiol. 119: 1005 (1984).

    PubMed  CAS  Google Scholar 

  14. J.E. Vena, S. Graham, M. Zielezny, M.K. Swanson, R.E. Barnes, and J. Nolan, Lifetime occupational exercise and colon cancer, Am J Epidemiol. 122: 357 (1985).

    PubMed  CAS  Google Scholar 

  15. M. Gerhardsson, S.E. Norell, H. Kiviranta, N.L. Pedersen, and A. Ahlbom, Sedentary jobs and colon cancer, Am J Epidemiol. 123: 775 (1986).

    PubMed  CAS  Google Scholar 

  16. J.E. Vena, S. Graham, M. Zielezny, J. Brasure, and M.K. Swanson, Occupational exercise and risk of cancer, Am J Clin Nutr. 45: 318 (1987).

    PubMed  CAS  Google Scholar 

  17. A. H. Wu, A. Paganini-Hill, R.K. Ross, and B.E. Henderson, Alcohol, physical activity, and other risk factors for colorectal cancer: A prospective study, Br J Cancer. 55: 687 (1987).

    Article  PubMed  CAS  Google Scholar 

  18. M.L. Slattery, M.C. Schumacher, K.R. Smith, D.W. West, and N. Abd-Elghany, Physical activity, diet, and risk of colon cancer in Utah, Am J Epidemiol. 128: 989 (1988).

    PubMed  CAS  Google Scholar 

  19. M. Gerhardsson, B. Floderus, and S. E. Norell, Physical activity and colon cancer risk, Int J Epidemiol. 17: 743 (1988).

    Article  PubMed  CAS  Google Scholar 

  20. R.K. Severson, A.M.Y. Nomura, J.S. Grove, and G.N. Stemmermann, A prospective analysis of physical activity and cancer, Am J Epidemiol. 130: 522 (1989).

    PubMed  CAS  Google Scholar 

  21. R.C. Brownson, S.H. Zahm, J.C. Chang, and A. Blair, Occupational risk of colon cancer. An analysis by anatomic subsite, Am J Epidemiol. 130: 675 (1989).

    PubMed  CAS  Google Scholar 

  22. D. Albanes, A. Blair, and P.R. Taylor, Physical activity and risk of cancer in the NHANES I population, Am J Public Health. 79: 744 (1989).

    Article  PubMed  CAS  Google Scholar 

  23. M. Fredriksson, N.O. Bengtsson, L. Hardell, and O. Axelson, Colon cancer, physical activity, and occupational exposures. A case-control study, Cancer. 63: 1838 (1989).

    Article  PubMed  CAS  Google Scholar 

  24. R.K. Peters, D.Y. Garabrant, M.C. Yu, and T.M. Mack, A case-control study of occupational and dietary factors in colorectal cancer in young men by subsite, Cancer Res. 49: 5459 (1989).

    PubMed  CAS  Google Scholar 

  25. R. Ballard-Barbash, A. Schatzkin, D. Albanes, M.H. Schiffman, B.E. Kreger, W.B. Kannel, K.M. Anderson, and W.E. Helsel, Physical activity and risk of large bowel cancer in the Framingham Study, Cancer Res. 50: 3610 (1990).

    PubMed  CAS  Google Scholar 

  26. M. Gerhardsson de Verdier, G. Steineck, U. Hagman, A. Rieger, and S.E. Norell, Physical activity and colon cancer: A case-referent study in Stockholm, Int J Cancer. 46: 985 (1990).

    Article  Google Scholar 

  27. A.S. Whittemore, A.H. Wu-Williams, M. Lee, Z. Shu, R.P. Gallagher, J. Deng-ao, Z. Lun, W. Xianghui, C. Kun, D. Jung, C.-Z. Teh, L. Chengde, X.J. Yao, R.S. Paffenbarger, Jr., and B.E. Henderson, Diet, physical activity, and colorectal cancer among Chinese in North America and China, J Natl Cancer Inst. 82: 915 (1990).

    Article  PubMed  CAS  Google Scholar 

  28. C. Huggins, and C.V. Hodges, Studies on prostatic cancer. I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate, Cancer Res. 1: 293 (1941).

    CAS  Google Scholar 

  29. D.G. Zaridze, and P. Boyle, Cancer of the prostate: epidemiology and aetiology, Br J Urol. 59: 493 (1987).

    Article  PubMed  CAS  Google Scholar 

  30. R. Ghanadian, C.M. Puah, and E.P.N. O’Donoghue, Serum testosterone and dihydrotestosterone in carcinoma of the prostate, Br J Cancer. 39: 696 (1979).

    Article  PubMed  CAS  Google Scholar 

  31. M.A. Jackson, J. Kovi, M.Y. Heshmat, T.A. Ogunmuyiwa, G. W. Jones, A.O. Williams, E.C. Christian, E.O. Nkposong, M.S. Rao, A.G. Jackson, and B.S. Ahluwalia, Characterization of prostatic carcinoma among blacks: a comparison between a low-incidence area, Ibadan, Nigeria, and a high-incidence area, Washington, DC, The Prostate. 1: 185 (1981).

    Article  Google Scholar 

  32. B. Ahluwalia, M.A. Jackson, G.W. Jones, A.O. Williams, M.S. Rao, and S. Rajguru, Blood hormone profiles in prostate cancer patients in high-risk and low-risk populations, Cancer. 48: 2267 (1981).

    Article  PubMed  CAS  Google Scholar 

  33. D.R. Cox, Regression models and life tables, J Roy Soc Stat. 34: 187 (1972).

    Google Scholar 

  34. E.L. Frome, The analysis of rates using Poisson regression models, Biometrics. 39: 665 (1983).

    Article  PubMed  CAS  Google Scholar 

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© 1992 Plenum Press, New York

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Paffenbarger, R.S., Lee, IM., Wing, A.L. (1992). The Influence of Physical Activity on the Incidence of Site-Specific Cancers in College Alumni. In: Jacobs, M.M. (eds) Exercise, Calories, Fat and Cancer. Advances in Experimental Medicine and Biology, vol 322. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7953-9_2

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  • DOI: https://doi.org/10.1007/978-1-4684-7953-9_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7955-3

  • Online ISBN: 978-1-4684-7953-9

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