Skip to main content
main-content

Tipp

Weitere Artikel dieser Ausgabe durch Wischen aufrufen

Erschienen in: Spektrum der Augenheilkunde 3/2013

01.06.2013 | bericht

Leitbild Diagnose und Therapie retinaler Venenverschlüsse

verfasst von: Martin Weger, Univ. Doz. Dr. Stefan Egger, für die Netzhautkommission

Erschienen in: Spektrum der Augenheilkunde | Ausgabe 3/2013

Einloggen, um Zugang zu erhalten
share
TEILEN

Auszug

Retinale Venenverschlüsse stellen die zweithäufigste Netzhautgefäßerkrankung nach der diabetischen Retinopathie dar. Je nach Lokalisation des Verschlusses unterscheidet man einen Zentral-, Hemiretinal- und Astvenenverschluss. Diese unterscheiden sich nicht nur in der Lokalisation des Verschlusses, sondern auch in der Visusprognose, Art und Prävalenz der Risikofaktoren und teils in den zur Verfügung stehenden Therapieoptionen. …
Literatur
1.
Zurück zum Zitat Rogers S, McIntosh RL, Cheung N, et al. The prevalence of retinal vein occlusion: pooled data from population studies from the United States, Europe, Asia and Australia. Ophthalmology. 2010;117:313–9. PubMedCrossRef Rogers S, McIntosh RL, Cheung N, et al. The prevalence of retinal vein occlusion: pooled data from population studies from the United States, Europe, Asia and Australia. Ophthalmology. 2010;117:313–9. PubMedCrossRef
2.
Zurück zum Zitat Hayreh SS, Zimmerman B, McCarthy MJ, Podhajsky P. Systemic diseases associated with various types of retinal vein occlusion. Am J Ophthalmol. 2001;131:61–77. PubMedCrossRef Hayreh SS, Zimmerman B, McCarthy MJ, Podhajsky P. Systemic diseases associated with various types of retinal vein occlusion. Am J Ophthalmol. 2001;131:61–77. PubMedCrossRef
3.
Zurück zum Zitat Hayreh SS, Zimmerman MB, Podhajsky P. Incidence of various types of retinal vein occlusion and their recurrence and demographic characteristics. Am J Ophthalmol. 1994;117:429–41. PubMed Hayreh SS, Zimmerman MB, Podhajsky P. Incidence of various types of retinal vein occlusion and their recurrence and demographic characteristics. Am J Ophthalmol. 1994;117:429–41. PubMed
4.
Zurück zum Zitat Deramo VA, Cox TA, Syed AB, Lee PP, Fekrat S. Vision-related quality of life in people with central retinal vein occlusion using the 25-item national eye institute visual function questionnaire. Arch Ophthalmol. 2003;121:1297–302. PubMedCrossRef Deramo VA, Cox TA, Syed AB, Lee PP, Fekrat S. Vision-related quality of life in people with central retinal vein occlusion using the 25-item national eye institute visual function questionnaire. Arch Ophthalmol. 2003;121:1297–302. PubMedCrossRef
5.
Zurück zum Zitat Awdeh RM, Elsing SH, Deramo VA, Stinnett S, Lee PP, Fekrat S. Vision-related quality of life in persons with unilateral branch retinal vein occlusion using the 25-item national eye institute visual function questionnaire. Br J Ophthalmol. 2010;94:319–23. PubMedCrossRef Awdeh RM, Elsing SH, Deramo VA, Stinnett S, Lee PP, Fekrat S. Vision-related quality of life in persons with unilateral branch retinal vein occlusion using the 25-item national eye institute visual function questionnaire. Br J Ophthalmol. 2010;94:319–23. PubMedCrossRef
6.
Zurück zum Zitat Cugati S, Wang JJ, Knudtson MD, et al. Retinal vein occlusion and vascular mortality: pooled data analysis of 2 population-based cohorts. Ophthalmology. 2007;114:520–4. PubMedCrossRef Cugati S, Wang JJ, Knudtson MD, et al. Retinal vein occlusion and vascular mortality: pooled data analysis of 2 population-based cohorts. Ophthalmology. 2007;114:520–4. PubMedCrossRef
7.
Zurück zum Zitat Werther W, Chu L, Holekamp N, Do DV, Rubio RG. Myocardial infarction and cerebrovascular accident in patients with retinal vein occlusion. Arch Ophthalmol. 2011;129:326–31. PubMedCrossRef Werther W, Chu L, Holekamp N, Do DV, Rubio RG. Myocardial infarction and cerebrovascular accident in patients with retinal vein occlusion. Arch Ophthalmol. 2011;129:326–31. PubMedCrossRef
8.
Zurück zum Zitat Ho JD, Liou SW, Lin HC. Retinal vein occlusion and the risk of stroke development: a five-year follow-up study. Am J Ophthalmol. 2009;137:283–90. CrossRef Ho JD, Liou SW, Lin HC. Retinal vein occlusion and the risk of stroke development: a five-year follow-up study. Am J Ophthalmol. 2009;137:283–90. CrossRef
9.
Zurück zum Zitat O’Mahoney PR, Wong DT, Ray JG. Retinal vein occlusion and traditional risk factors for atherosclerosis. Arch Ophthalmol. 2008;126:692–9. PubMedCrossRef O’Mahoney PR, Wong DT, Ray JG. Retinal vein occlusion and traditional risk factors for atherosclerosis. Arch Ophthalmol. 2008;126:692–9. PubMedCrossRef
10.
Zurück zum Zitat Stojakovic T, Scharnagl H, März W, Winkelmann BR, Boehm BO, Schmut O. Low density lipoprotein triglycerides and lipoprotein(a) are risk factors for retinal vascular occlusion. Clin Chim Acta. 2007;382:77–81. PubMedCrossRef Stojakovic T, Scharnagl H, März W, Winkelmann BR, Boehm BO, Schmut O. Low density lipoprotein triglycerides and lipoprotein(a) are risk factors for retinal vascular occlusion. Clin Chim Acta. 2007;382:77–81. PubMedCrossRef
11.
Zurück zum Zitat The Eye Disease Case-Control Study Group. Risk factors for central retinal vein occlusion. Arch Ophthalmol. 1996;114:545–54. CrossRef The Eye Disease Case-Control Study Group. Risk factors for central retinal vein occlusion. Arch Ophthalmol. 1996;114:545–54. CrossRef
12.
Zurück zum Zitat The Eye Disease Case-Control Study Group. Risk factors for branch retinal vein occlusion. Am J Ophthalmol. 1993;116:286–96. The Eye Disease Case-Control Study Group. Risk factors for branch retinal vein occlusion. Am J Ophthalmol. 1993;116:286–96.
13.
Zurück zum Zitat Hayreh SS, Zimmerman MB, Beri M, Podhajsky P. Intraocular pressure abnormalities associated with central and hemiretinal vein occlusion. Ophthalmology. 2004;111:133–41. PubMedCrossRef Hayreh SS, Zimmerman MB, Beri M, Podhajsky P. Intraocular pressure abnormalities associated with central and hemiretinal vein occlusion. Ophthalmology. 2004;111:133–41. PubMedCrossRef
14.
Zurück zum Zitat Kimmel AS, McCarthy MJ, Blodi CF, Folk JC. Branch retinal vein occlusion in sarcoidosis. Am J Ophthalmol. 1989;107:561–2. PubMed Kimmel AS, McCarthy MJ, Blodi CF, Folk JC. Branch retinal vein occlusion in sarcoidosis. Am J Ophthalmol. 1989;107:561–2. PubMed
15.
Zurück zum Zitat Lobes LA Jr, Folk JC. Syphilitic phlebitis simulating branch vein occlusion. Ann Ophthalmol. 1981;13:825–7. PubMed Lobes LA Jr, Folk JC. Syphilitic phlebitis simulating branch vein occlusion. Ann Ophthalmol. 1981;13:825–7. PubMed
16.
Zurück zum Zitat The Central Vein Occlusion Study Group. Natural history and clinical management of central retinal vein occlusion. Arch Ophthalmol. 1997;115:486–91. CrossRef The Central Vein Occlusion Study Group. Natural history and clinical management of central retinal vein occlusion. Arch Ophthalmol. 1997;115:486–91. CrossRef
17.
Zurück zum Zitat Consensus Statement. Retinaler Venenverschluss (RVV). Diagnostik und Therapie. Österreichische Ärztezeitung 2012; Supplementum Februar:1–11. Consensus Statement. Retinaler Venenverschluss (RVV). Diagnostik und Therapie. Österreichische Ärztezeitung 2012; Supplementum Februar:1–11.
18.
Zurück zum Zitat The Branch Vein Occlusion Study Group. Argon laser photocoagulation for macular edema in branch vein occlusion. Am J Ophthalmol. 1984;98:271–82. The Branch Vein Occlusion Study Group. Argon laser photocoagulation for macular edema in branch vein occlusion. Am J Ophthalmol. 1984;98:271–82.
19.
Zurück zum Zitat Gutman FA, Zegarra H. The natural course of temporal retinal branch vein occlusion. Trans Am Acad Ophthalmol Otolaryngol. 1974;78:OP178–92. Gutman FA, Zegarra H. The natural course of temporal retinal branch vein occlusion. Trans Am Acad Ophthalmol Otolaryngol. 1974;78:OP178–92.
20.
Zurück zum Zitat Michels RG, Gass JD. The natural course of retinal branch vein obstruction. Trans Am Acad Ophthalmol Otolaryngol. 1974;87:OP166–77. Michels RG, Gass JD. The natural course of retinal branch vein obstruction. Trans Am Acad Ophthalmol Otolaryngol. 1974;87:OP166–77.
21.
Zurück zum Zitat Hayreh SS, Zimmerman MB. Hemicentral retinal vein occlusion: natural history of visual outcome. Retina. 2012;32:68–76. PubMedCrossRef Hayreh SS, Zimmerman MB. Hemicentral retinal vein occlusion: natural history of visual outcome. Retina. 2012;32:68–76. PubMedCrossRef
22.
Zurück zum Zitat Funk M, Kriechbaum K, Prager F, et al. Intraocular concentrations of growth factors and cytokines in retinal vein occlusion and the effect of therapy with bevacizumab. Invest Ophthalmol Vis Sci. 2009;50:1025–32. PubMedCrossRef Funk M, Kriechbaum K, Prager F, et al. Intraocular concentrations of growth factors and cytokines in retinal vein occlusion and the effect of therapy with bevacizumab. Invest Ophthalmol Vis Sci. 2009;50:1025–32. PubMedCrossRef
23.
Zurück zum Zitat Lim JW. Intravitreal bevacizumab and cytokine levels in major and macular branch retinal vein occlusion. Ophthalmologica. 2011;225:150–4. PubMedCrossRef Lim JW. Intravitreal bevacizumab and cytokine levels in major and macular branch retinal vein occlusion. Ophthalmologica. 2011;225:150–4. PubMedCrossRef
24.
Zurück zum Zitat Koss MJ, Pfister M, Rothweiler F, et al. Comparison of cytokine levels from undiluted vitreous of untreated patients with retinal vein occlusion. Acta Ophthalmol. 2012;90(2):e98–e103. doi: 10.1111/j.1755-3768.2011.02292.x. PubMedCrossRef Koss MJ, Pfister M, Rothweiler F, et al. Comparison of cytokine levels from undiluted vitreous of untreated patients with retinal vein occlusion. Acta Ophthalmol. 2012;90(2):e98–e103. doi: 10.1111/j.1755-3768.2011.02292.x. PubMedCrossRef
25.
Zurück zum Zitat Campochiaro PA, Heier JS, Feiner L, et al. Ranibizumab for macular edema following branch retinal vein occlusion: six-month primary end point results of a phase III study. Ophthalmology. 2010;117:1102–12. PubMedCrossRef Campochiaro PA, Heier JS, Feiner L, et al. Ranibizumab for macular edema following branch retinal vein occlusion: six-month primary end point results of a phase III study. Ophthalmology. 2010;117:1102–12. PubMedCrossRef
26.
Zurück zum Zitat Brown DM, Campochiaro PA, Bhisitkul RB, et al. Sustained benefits from ranibizumab for macular edema following branch retinal vein occlusion: 12-month outcomes of a phase III study. Ophthalmology. 2011;118:1594–602. PubMedCrossRef Brown DM, Campochiaro PA, Bhisitkul RB, et al. Sustained benefits from ranibizumab for macular edema following branch retinal vein occlusion: 12-month outcomes of a phase III study. Ophthalmology. 2011;118:1594–602. PubMedCrossRef
27.
Zurück zum Zitat Brown DM, Campochiaro PA, Singh RP, et al. Ranibizumab for macular edema following central retinal vein occlusion: six-month primary end point results of a phase III study. Ophthalmology. 2010;117:1124–33. PubMedCrossRef Brown DM, Campochiaro PA, Singh RP, et al. Ranibizumab for macular edema following central retinal vein occlusion: six-month primary end point results of a phase III study. Ophthalmology. 2010;117:1124–33. PubMedCrossRef
28.
Zurück zum Zitat Campochiaro PA, Brown DA, Awh CC, et al. Sustained benefits from ranibizumab for macular edema following central retinal vein occlusion: twelve-month outcomes of a phase III study. Ophthalmology. 2011;118:2041–9. PubMedCrossRef Campochiaro PA, Brown DA, Awh CC, et al. Sustained benefits from ranibizumab for macular edema following central retinal vein occlusion: twelve-month outcomes of a phase III study. Ophthalmology. 2011;118:2041–9. PubMedCrossRef
29.
Zurück zum Zitat Heier JS, Campochiaro PA, Yau L, et al. Ranibizumab for macular edema due to retinal vein occlusions: long-term follow-up in the HORIZON trial. Ophthalmology. 2012;119:802–9. PubMedCrossRef Heier JS, Campochiaro PA, Yau L, et al. Ranibizumab for macular edema due to retinal vein occlusions: long-term follow-up in the HORIZON trial. Ophthalmology. 2012;119:802–9. PubMedCrossRef
30.
Zurück zum Zitat Prager F, Michels S, Kriechbaum K, et al. Intravitreal bevacizumab (Avastin) for macular oedema secondary to retinal vein occlusion: 12-month results of a prospective clinical trial. Br J Ophthalmol. 2009;93:452–6. PubMedCrossRef Prager F, Michels S, Kriechbaum K, et al. Intravitreal bevacizumab (Avastin) for macular oedema secondary to retinal vein occlusion: 12-month results of a prospective clinical trial. Br J Ophthalmol. 2009;93:452–6. PubMedCrossRef
31.
Zurück zum Zitat Wu L, Arevalo JF, Berrocal MH, et al. Comparison of two doses of intravitreal bevacizumab as primary treatment for macular edema secondary to branch retinal vein occlusions: results of the Pan American Collaborative Retina Study Group at 24 months. Retina. 2009;29:1396–403. PubMedCrossRef Wu L, Arevalo JF, Berrocal MH, et al. Comparison of two doses of intravitreal bevacizumab as primary treatment for macular edema secondary to branch retinal vein occlusions: results of the Pan American Collaborative Retina Study Group at 24 months. Retina. 2009;29:1396–403. PubMedCrossRef
32.
Zurück zum Zitat Wu L, Arevalo JF, Berrocal MH, et al. Comparison of two doses of intravitreal bevacizumab as primary treatment for macular edema secondary to central retinal vein occlusions: results of the Pan American Collaborative Retina Study Group at 24 months. Retina. 2010;30:1002–11. PubMedCrossRef Wu L, Arevalo JF, Berrocal MH, et al. Comparison of two doses of intravitreal bevacizumab as primary treatment for macular edema secondary to central retinal vein occlusions: results of the Pan American Collaborative Retina Study Group at 24 months. Retina. 2010;30:1002–11. PubMedCrossRef
33.
Zurück zum Zitat Kreutzer TC, Alge CS, Wolf AH, et al. Intravitreal bevacizumab for the treatment of macular oedema secondary to branch retinal vein occlusion. Br J Ophthalmol. 2008;92:351–5. PubMedCrossRef Kreutzer TC, Alge CS, Wolf AH, et al. Intravitreal bevacizumab for the treatment of macular oedema secondary to branch retinal vein occlusion. Br J Ophthalmol. 2008;92:351–5. PubMedCrossRef
34.
Zurück zum Zitat Priglinger SG, Wolf AH, Kreutzer TC, et al. Intravitreal bevacizumab injections for treatment of central retinal vein occlusion: six-month results of a prospective trial. Retina. 2007;27:1004–12. PubMedCrossRef Priglinger SG, Wolf AH, Kreutzer TC, et al. Intravitreal bevacizumab injections for treatment of central retinal vein occlusion: six-month results of a prospective trial. Retina. 2007;27:1004–12. PubMedCrossRef
35.
Zurück zum Zitat Wroblewski JJ, Wells JA 3rd, Adamis AP, et al. Pegaptanib sodium for macular edema secondary to central retinal vein occlusion. Arch Ophthalmol. 2009;127:374–80. PubMedCrossRef Wroblewski JJ, Wells JA 3rd, Adamis AP, et al. Pegaptanib sodium for macular edema secondary to central retinal vein occlusion. Arch Ophthalmol. 2009;127:374–80. PubMedCrossRef
36.
Zurück zum Zitat Wroblewski JJ, Wells JA 3rd, Gonzales CR. Pegaptanib sodium for macular edema secondary to branch retinal vein occlusion. Am J Ophthalmol. 2010;149:147–54. PubMedCrossRef Wroblewski JJ, Wells JA 3rd, Gonzales CR. Pegaptanib sodium for macular edema secondary to branch retinal vein occlusion. Am J Ophthalmol. 2010;149:147–54. PubMedCrossRef
37.
Zurück zum Zitat Clark W. VEGF Trap-Eye for Retinal Vein Occlusion: COPERNICUS and GALLILEO, American Academy of Ophthalmology 2011. Clark W. VEGF Trap-Eye for Retinal Vein Occlusion: COPERNICUS and GALLILEO, American Academy of Ophthalmology 2011.
38.
Zurück zum Zitat Boyer D, Heier J, Brown DM, et al. Vascular endothelial growth factor Trap-Eye for macular edema secondary to central retinal vein occlusion: six-month results of the phase 3 COPERNICUS study. Ophthalmology. 2012;119:1024–32. PubMedCrossRef Boyer D, Heier J, Brown DM, et al. Vascular endothelial growth factor Trap-Eye for macular edema secondary to central retinal vein occlusion: six-month results of the phase 3 COPERNICUS study. Ophthalmology. 2012;119:1024–32. PubMedCrossRef
39.
Zurück zum Zitat Yoshimura T, Sonoda KH, Sugahara M, et al. Comprehensive analysis of inflammatory immune mediators in vitreoretinal diseases. PLoS One. 2009;4:e8158. PubMedCrossRef Yoshimura T, Sonoda KH, Sugahara M, et al. Comprehensive analysis of inflammatory immune mediators in vitreoretinal diseases. PLoS One. 2009;4:e8158. PubMedCrossRef
40.
Zurück zum Zitat Nehme A, Edelman J. Dexamethasone inhibits high glucose-, TNF-alpha-, and IL-1 beta induced secretion of inflammatory and angiogenic mediators from retinal microvascular pericytes. Invest Ophthalmol Vis Sci. 2008;49:2030–8. PubMedCrossRef Nehme A, Edelman J. Dexamethasone inhibits high glucose-, TNF-alpha-, and IL-1 beta induced secretion of inflammatory and angiogenic mediators from retinal microvascular pericytes. Invest Ophthalmol Vis Sci. 2008;49:2030–8. PubMedCrossRef
41.
Zurück zum Zitat McAllister IL, Vijaysekaran S, Chen SD, Yu DY. Effect of triamcinolone acetonide on vascular endothelial growth factor and occludin levels in branch retinal vein occlusion. Am J Ophthalmol. 2009;147:838–46. PubMedCrossRef McAllister IL, Vijaysekaran S, Chen SD, Yu DY. Effect of triamcinolone acetonide on vascular endothelial growth factor and occludin levels in branch retinal vein occlusion. Am J Ophthalmol. 2009;147:838–46. PubMedCrossRef
42.
Zurück zum Zitat Scott IU, Ip MS, VanVeldhuisen PC, et al. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with standard care to treat vision loss associated with macular edema secondary to branch retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 6. Arch Ophthalmol. 2009;127:1115–28. PubMedCrossRef Scott IU, Ip MS, VanVeldhuisen PC, et al. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with standard care to treat vision loss associated with macular edema secondary to branch retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 6. Arch Ophthalmol. 2009;127:1115–28. PubMedCrossRef
43.
Zurück zum Zitat Ip MS, Scott IU, VanVeldhuisen PC, et al. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with observation to treat vision loss associated with macular edema secondary to central retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 5. Arch Ophthalmol. 2009;127:1101–14. PubMedCrossRef Ip MS, Scott IU, VanVeldhuisen PC, et al. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with observation to treat vision loss associated with macular edema secondary to central retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 5. Arch Ophthalmol. 2009;127:1101–14. PubMedCrossRef
44.
Zurück zum Zitat Haller JA, Bandello F, Belfort R Jr, et al. Dexamethasone intravitreal implant in patients with macular edema related to branch or central retinal vein occlusion: twelve month study results. Ophthalmology. 2011;118:2453–60. PubMedCrossRef Haller JA, Bandello F, Belfort R Jr, et al. Dexamethasone intravitreal implant in patients with macular edema related to branch or central retinal vein occlusion: twelve month study results. Ophthalmology. 2011;118:2453–60. PubMedCrossRef
45.
Zurück zum Zitat The Central Vein Occlusion Study Group M report. Evaluation of grid pattern photocoagulation for macular edema in central retinal vein occlusion. Ophthalmology. 1995;102(10):1425–33. The Central Vein Occlusion Study Group M report. Evaluation of grid pattern photocoagulation for macular edema in central retinal vein occlusion. Ophthalmology. 1995;102(10):1425–33.
46.
Zurück zum Zitat The Central Vein Occlusion Study Group N report. A randomized clinical trial of early panretinal photocoagulation for ischemic central vein occlusion. Ophthalmology. 1995;102:1434–44. The Central Vein Occlusion Study Group N report. A randomized clinical trial of early panretinal photocoagulation for ischemic central vein occlusion. Ophthalmology. 1995;102:1434–44.
47.
Zurück zum Zitat Stellungnahme der Deutschen Ophthalmologischen Gesellschaft, der Retinologischen Gesellschaft und des Berufsverbandes der Augenärzte Deutschlands zur Therapie des Makulaödems beim retinalen Venenverschluss. 2010. http://​www.​dog.​org.​ Zugriffsdaten: 29.11.2011 Stellungnahme der Deutschen Ophthalmologischen Gesellschaft, der Retinologischen Gesellschaft und des Berufsverbandes der Augenärzte Deutschlands zur Therapie des Makulaödems beim retinalen Venenverschluss. 2010. http://​www.​dog.​org.​ Zugriffsdaten: 29.11.2011
Metadaten
Titel
Leitbild Diagnose und Therapie retinaler Venenverschlüsse
verfasst von
Martin Weger
Univ. Doz. Dr. Stefan Egger
für die Netzhautkommission
Publikationsdatum
01.06.2013
Verlag
Springer Vienna
Erschienen in
Spektrum der Augenheilkunde / Ausgabe 3/2013
Print ISSN: 0930-4282
Elektronische ISSN: 1613-7523
DOI
https://doi.org/10.1007/s00717-012-0128-3

Weitere Artikel der Ausgabe 3/2013

Spektrum der Augenheilkunde 3/2013 Zur Ausgabe

kongresskalender

KONGRESSKALENDER