A review of the recent changes in understanding of laryngopharyngeal and extra-oesophageal reflux symptoms.
Literature search over 7 years (2008–2015) and relevant historical cited articles.
Modern investigation more clearly shows a subgroup of patients with intermittent full column oesophago-gastric-reflux-causing symptoms. Multiple other sites in the lung, head and neck may also be implicated in the reflux disease process.
Understanding of extra-oesophageal reflux symptomology is evolving. New equipment and techniques suggest further areas of research, and as yet effective therapy remains elusive for some.