Systemic sclerosis (SSc) is a rare disease that is classified within the connective tissue disease spectrum [ 1 ]. Diffuse cutaneous SSc (dcSSc) and limited cutaneous SSc (lcSSc) are the two major SSc groups based on the affected organ systems and …
In the past 12 months a plethora of relevant novel data for the treatment of metastatic HER2 positive breast cancer were published. To bring this new evidence into a clinical perspective, a group of Austrian breast cancer specialists updated their …
verfasst von:
PD Dr. Gabriel Rinnerthaler, Univ. Prof. Dr. Christian Singer, Univ. Prof. Dr. Edgar Petru, OA Dr. Daniel Egle, Prim. Univ. Prof. Dr. Andreas Petzer, OÄ Dr. Ursula Pluschnig, PD Dr. Simon Peter Gampenrieder, Assoc. Prof. PD Dr. Georg Pfeiler, Univ. Prof. Dr. Michael Gnant, Prim. PD Dr. Birgit Grünberger, Prim. Univ.-Doz. Dr. Peter Krippl, PD Dr. Kathrin Strasser-Weippl, OA PD DDr. Christoph Suppan, OÄ Dr. Christine Brunner, OÄ Dr. Renate Pusch, OÄ Dr. Margit Sandholzer, Assoc. Prof. PD Dr. Marija Balic, Assoc. Prof. PD Dr. Rupert Bartsch
Diabetes mellitus is a global burden with massive economic costs. Around 12% of global expenditure on health is assigned to the care of individuals with diabetes mellitus (DM) and its related complications [ 1 ]. In 2020, 463 million adults …
verfasst von:
MD Teresa Gisinger, MD Prof. Alexandra Kautzky-Willer, PhD MSc Priv. Doz. Dr. Michael Leutner
diseases induced by aeroallergens are civilizational diseases with a continuously increasing prevalence [ 1 ]. These diseases can show various clinical manifestations, with allergic rhinitis and asthma being statistically the most important. The …
verfasst von:
MD, PhD. Assoc. prof. Slavomír Perečinský, MD Lenka Murínová, MD Andrea Jančová, MD, PhD. Pavol Murín, MD Katarína Perečinská, MD, PhD. Marek Varga, MSc, PhD. Bronislava Víchová, MD Erik Pačuta, MD, PhD. Assoc. prof. Mária Rašiová, MD, PhD. prof. Ľubomír Legáth
Peripheral arterial disease (PAD) is defined as a vascular disease characterized by narrowing and obstruction of arteries distal to the abdominal aorta and bifurcation level as a consequence of progressive atherosclerosis. The frequency of PAD …
Severe acute respiratory syndrome corona virus 2 (SARS-CoV2) has caused a global pandemic resulting in deaths in excess of about 3 million [ 1 ]. Since the first clinical cases of coronavirus disease 2019 (COVID-19) emerged in late 2019 [ 2 ], it …
verfasst von:
Benedikt Rumpf, Benno Lickefett, Clemens Baumgartner, Victoria Kauer, Mario Karolyi, Erich Pawelka, Tamara Seitz, Marianna Traugott, Petr Triska, Andreas Bergthaler, Hermann Laferl, Christoph Wenisch, Alexander Zoufaly
Impaired exercise capacity substantially affects patients with chronic obstructive pulmonary disease (COPD), but airflow limitation shows only a weak association [ 1 – 3 ]. Rather more is oxidative capacity in muscle tissue of COPD patients …
Analysis from six outpatient clinics in Austria 2019
In most countries of the world, chronic kidney disease (CKD) is more prevalent among women than men [ 1 ]. Specifically, when we summarized data from population-based studies of 21 countries [ 2 – 24 ] for our earlier review article [ 1 ], we …
verfasst von:
Michal J. Lewandowski, Simon Krenn, Amelie Kurnikowski, Philipp Bretschneider, Martina Sattler, Elisabeth Schwaiger, Marlies Antlanger, Philipp Gauckler, Markus Pirklbauer, Maria Brunner, Sabine Horn, Emanuel Zitt, Bernhard Kirsch, Martin Windpessl, Manfred Wallner, Ida Aringer, Martin Wiesholzer, Manfred Hecking, MSc Sebastian Hödlmoser
This publication provides a thorough analysis of the most relevant topics concerning the management of latent tuberculosis when using biologic and targeted synthetic Disease Modifying Antirheumatic Drugs (DMARDs) by a multidisciplinary, select …
verfasst von:
Eva Rath, Michael Bonelli, Christina Duftner, Johann Gruber, Peter Mandl, Florentine Moazedi-Furst, Herwig Pieringer, Rudolf Puchner, Holger Flick, Helmut J. F. Salzer, Günter Weiss, Stefan Winkler, Hans Skvara, Alexander Moschen, Harald Hofer, Julia Feurstein, MD Judith Sautner
Acute ischemic stroke in patients younger than the age of 50 years is a rare occurrence that results in high mortality and substantial loss of functional years of life. Internal carotid artery dissection (CAD) presents a rare, but serious …
The onset of the coronavirus disease 2019 (COVID-19) pandemic along with the implementation of lockdowns, social and physical distancing, and stay at home orders has drastically altered peoples’ lives and impacted global, public, and private …
verfasst von:
D.Sc. Assoc. Prof. PD. Dr. Benedikt Till, M.D., Ph.D., M.M.Sc. Assoc. Prof. PD. Dr. Thomas Niederkrotenthaler
From August 2021 to 7 March 2022, New York City prohibited indoor dining in restaurants selectively for persons who had not received a Coronavirus disease 2019 (COVID-19) vaccine. However, vaccinated persons may also be actively infected and …
verfasst von:
M.D. Dr. Gary P. Wormser, Ph.D. Dr. Paul Visintainer
Little is known about the impact of red blood cell distribution width (RDW) values on admission and Charlson Comorbidity Index (CCI) scores in polytraumatized patients, especially regarding the late-phase survival. A recent study showed that even …
verfasst von:
Valerie Weihs, Stephan Frenzel, Michél Dedeyan, Thomas Heinz, Stefan Hajdu, Martin Frossard
Borrelial lymphocytoma is a rare cutaneous manifestation of early localized European Lyme borreliosis. It manifests as a nodule or plaque with a diameter of up to a few centimeters. The lesion is, as a rule, solitary. It is more common in children …
Many deaths and a great consumption of healthcare resources are a consequence of sepsis [ 1 , 2 ]. Different pathophysiological pathways are involved in sepsis, including apoptosis [ 3 , 4 ]. Apoptosis is a programmed and active form of cell death …
verfasst von:
Leonardo Lorente, María M. Martín, Raquel Ortiz-López, Antonia Pérez-Cejas, Fuensanta Gómez-Bernal, Adriana González-Mesa, Alejandro Jiménez, Agustín F. González-Rivero
Novel SARS-CoV‑2 disease (COVID-19) is a tremendous global health burden leading to substantial morbidity and mortality, especially among patients with established chronic diseases [ 1 , 2 ]. Chronic kidney disease (CKD) is one of the important …
verfasst von:
Josipa Domjanović, MD Andrija Matetic, Darija Baković Kramarić, Tea Domjanović Škopinić, Dijana Borić Škaro, Nikola Delić, Frane Runjić, Ivo Jeličić