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Wiener klinische Wochenschrift OnlineFirst articles

09.12.2019 | original article Open Access

Polymerase chain reaction for the diagnosis of herpesvirus infections in dermatology

Analysis of clinical data

Human herpesvirus (HHV) infections are common worldwide. Clinically, herpes simplex virus 1 and 2 (HSV‑1 and HSV‑2, respectively) and varicella zoster virus (VZV) result in a range of diseases involving the skin and mucous membranes, occasionally …

MD Verena Schremser, MD Lukasz Antoniewicz, MD Erwin Tschachler, MD Assoc. Prof. Dr. Alexandra Geusau

09.12.2019 | original article

Relationship between psychological stress and metabolism in morbidly obese individuals

Obesity prevalence rates have increased dramatically in the last few decades. In a recent study with a representative sample of 14,685 adults from 16 European countries 12.8% were obese (body mass index, BMI ≥30 kg/m 2 ) with 10% classified as …

Friedrich Riffer, Ph.D. Manuel Sprung, Hannah Münch, Elmar Kaiser, Lore Streibl, Kathrin Heneis, Alexandra Kautzky-Willer

04.12.2019 | original article Open Access

Vitamin D assessment in perioperative medicine and critical care

A prospective observational pilot study

Low vitamin D status was reported to be significantly associated with a poor outcome in critically ill patients in several studies over the last decade [ 1 – 3 ]. These findings led to the performance of one large randomized clinical trial of …

MD Paul Zajic, MD PhD Stefan Heschl, MD Michael Schörghuber, MD Petra Srekl-Filzmaier, MD Tatjana Stojakovic, MD Viktoria Weixler, MSc Sieglinde Zelzer, MD Karin Amrein

29.11.2019 | original article Open Access

Relevant parameters for recommendations of physical activity in patients suffering from multiple myeloma

A pilot study

Multiple myeloma is the second most common hematologic malignancy [ 1 ]. Patients suffering from multiple myeloma show an increase in cancer-specific survival rate due to modern cancer treatment [ 2 , 3 ]. Regular physical activity and exercise are …

Fadime Cenik, Mohammad Keilani, Timothy Hasenöhrl, Dominikus Huber, Bianca Stuhlpfarrer, Anna Pataraia, MBA, MMSc Univ. Prof. Dr. Richard Crevenna

28.11.2019 | original article

Impact of hemodialysis on liver stiffness measured with real-time two-dimensional shear wave elastography

Chronic kidney disease is a major public health problem. The incidence and prevalence of chronic kidney diseases is increasing worldwide [ 1 ]. Several studies suggest that by the year 2030 over 2 million people will be treated with hemodialysis …

Danijela Zjacic Puljiz, Antonio Mestrovic, Ivan Zaja, MD, PhD Ante Tonkic, Ivica Grgurevic, Darko Duplancic, Ivana Kristina Delic Jukic, Dragan Ljutic, Zeljko Puljiz

27.11.2019 | original article

IntrahospitalIntrahospital mortality of influenza patients during the 2017–2018 influenza season

Report from a tertiary care hospital in Austria

In the northern hemisphere seasonal influenza is responsible for excess mortality and morbidity [ 1 – 4 ]. In Austria, influenza activity is observed using a Sentinella surveillance system. In this system, estimated rates of influenza are …

Florian Obendorf, Carmen Klammer, Matthias Heinzl, Margot Egger-Salmhofer, Michael Resl, Benjamin Dieplinger, Martin Clodi

26.11.2019 | original article Open Access

When an incidental MRI finding becomes a clinical issue

Posterior lumbar subcutaneous edema in degenerative, inflammatory, and infectious conditions of the lumbar spine

Edema-like signal changes in the deep subcutaneous, perifascial soft tissue of the posterior lumbar spine or simply posterior lumbar subcutaneous edema (PLSE), are frequently depicted on routinely performed spinal magnetic resonance imaging (MRI) …

MD Ursula Schwarz-Nemec, MD Klaus M. Friedrich, MD Michael A. Arnoldner, MS Felix K. Schwarz, PhD Michael Weber, MD Siegfried Trattnig, MD Josef G. Grohs, MD Stefan F. Nemec

26.11.2019 | review article

Diagnosis and treatment of hypothyroidism in old people

A new old challenge

Thyroid-stimulating hormone (thyrotropin, TSH) plays an essential role in the regulation of thyroid hormone release and development of the thyroid gland. Release of TSH is controlled by the hypothalamic-pituitary axis and stimulates the thyroid …

Antonio Maria Borzì, Antonio Biondi, Francesco Basile, PhD Marco Vacante

18.11.2019 | original article

Assessing the health-related quality of life in type 2 diabetes patients treated with insulin and oral antidiabetic agents

According to World Health Organization (WHO) data, the prevalence of diabetes has quadrupled to reach 422 million patients with diabetes in 2014, compared to only 108 million in 1980. In 2012, diabetes was the direct cause of death in …

Nawras Al-Taie, Delia Maftei, Alexandra Kautzky-Willer, Michael Krebs, Harald Stingl

11.11.2019 | short report

Neutral effect of Glioma-associated oncogene-1 expression on survival in myelofibrosis

This study retrospectively analyzed glioma-associated oncogene 1 (GLI‑1) mRNA expression in unfractionated bone marrow aspirates of 32 patients with myelofibrosis and 16 controls. It was found that GLI‑1 expression did not significantly differ …

MD PhD Marko Lucijanic, Ana Livun, Katarina Marija Tupek, Tajana Stoos-Veic, Vlatko Pejsa, Zeljko Jonjic, Amina Fazlic Dzankic, Marija Ivic, Rajko Kusec

11.11.2019 | main topic Open Access

Functional outcome after recurrent patellar dislocation

Comparison of two surgical techniques—Medial patellofemoral ligament reconstruction (MPFL) vs. Elmslie Trillat procedure

Patellar dislocation is a condition which occurs especially among physically active persons [ 1 ]. It has been reported as accounting for 2–3% of all acute knee injuries [ 1 ]. The surgical procedures for the treatment of patellar dislocation alter …

Dr. Mohammad Keilani, Stefano Palma, Richard Crevenna, Camilla Gaudart, Timothy Hasenöhrl, Martin Reschl, Nadine Huto, Stefan Hajdu, Harald K. Widhalm

07.11.2019 | original article Open Access

More pesticides—less children?

A previously presented study investigated the impact of recent pesticide exposure on cytological signs of genotoxicity and on symptoms of intoxication in 71 male coffee workers in the Dominican Republic. An unexpected finding of this study was …

Hanns Moshammer, Michael Poteser, Hans-Peter Hutter

07.11.2019 | review article

Update on hyperbaric oxygen therapy in burn treatment

Hyperbaric oxygen therapy (HBOT) has been shown to improve tissue hypoxia, neovascularization and ischemia reperfusion injury and reduce pathologic inflammation in various clinical settings and was proposed to be a game changer in treatment of …

MD Laurenz Weitgasser, MD Gerald Ihra, MD Bruno Schäfer, MD Klaus Markstaller, MD PhD Christine Radtke

05.11.2019 | original article

Prospective associations of cardiovascular disease with physical performance and disability

A longitudinal cohort study in the Osteoarthritis Initiative

Global population ageing is a leading public health concern given the increased risk of chronic conditions associated with older age. Cardiovascular conditions are common and their consequences are of clinical importance [ 1 ]. Cardiovascular …

Nicola Veronese, Brendon Stubbs, Sarah E Jackson, Ai Koyanagi, Vania Noventa, Francesco Bolzetta, Alberto Cester, Pinar Soysal, Stefania Maggi, Guillermo F. López-Sánchez, Mike Loosemore, Jacopo Demurtas, Lee Smith

30.10.2019 | original article

Telemedically augmented palliative care

Empowerment for patients with advanced cancer and their family caregivers

According to the World Health Organization (WHO) palliative care is the active total care of patients whose disease is not responsive to curative treatment [ 1 ]. The goal is the achievement of the best possible quality of life (QoL) for patients …

Romina Nemecek, Patrick Huber, Sophie Schur, Eva Katharina Masel, Lukas Baumann, Christoph Hoeller, Herbert Watzke, Michael Binder

24.10.2019 | original article Open Access

Low seroprotection rate for meningococcus serogroup C in the adult HIV-1-infected population in Austria

Current Advisory Committee on Immunization Practices (ACIP) guidelines recommend immunization of all human immunodeficiency virus (HIV)-infected patients against meningitis serotype ACWY due to recent outbreaks of meningitis C in homosexual men in …

Katharina Grabmeier-Pfistershammer, Kay Holleis, Sandra Rosskopf, Peter Steinberger, Veronique Touzeau-Roemer, Wolfgang Poeppl, Armin Rieger

22.10.2019 | Correction

Correction to: Analysis and quantification of bone healing after open wedge high tibial osteotomy

Correction to: Wien Klin Wochenschr 2019 original version of this article unfortunately contained a mistake. The presentation of Tab. 4 was incorrect. The corrected table is given below.The original …

E. Nemecek, C. Chiari, A. Valentinitsch, F. Kainberger, G. Hobusch, A. Kolb, L. Hirtler, C. Trost, S. Vukicevic, Prof. Dr. R. Windhager

16.10.2019 | original article

Olaratumab plus anthracyline in advanced/metastatic soft tissue sarcoma

Data of real-world utilization in Austria

Soft tissue sarcomas (STS) are a rare and heterogeneous group of solid tumors originating from mesenchymal precursors and comprise less than 1% of all newly diagnosed adult malignancies [ 1 ]. The STS present as a wide histopathological spectrum …

MD PhD Andreas Seeber, Lukas Weiss, Franz Romeder, Joanna Szkandera, Thomas Kuehr, Susanne Kostner, Petra Pichler, Thomas Jaeger, Florian Kocher, Richard Greil, Thomas Brodowicz

14.10.2019 | original article

Medical radiation exposure from radiological and interventional procedures in Austria

Since 1988 the number of diagnostic (plain radiography, fluoroscopy, computed tomography [CT]) and interventional procedures involving X‑rays and the associated collective dose has risen sharply internationally. One of the factors that contributed …

David Wachabauer, Stefan Mathis-Edenhofer, Hanns Moshammer

23.09.2019 | review article Open Access

What is new in the 2018 ESC guidelines for the management of cardiovascular diseases during pregnancy?

Cardiovascular diseases during pregnancy are the most common causes of pregnancy-associated mortality.Vaginal delivery is the preferred mode of birth in the majority of pregnancies.It is recommended that patients with modified World Health …

MD Irene M. Lang