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Erschienen in: Wiener klinische Wochenschrift 8/2016

01.12.2016 | original article

Is iron-deficiency anemia associated with migraine? Is there a role for anxiety and depression?

verfasst von: Prof. Dr. Gülsüm Emel Pamuk, MD, Mehmet Şerif Top, MD, Mehmet Şevki Uyanık, MD, Hilal Köker, MD, Mustafa Akker, MD, Recep Ak, MD, Ömer Atalay Yürekli, MD, Yahya Çelik, MD

Erschienen in: Wiener klinische Wochenschrift | Sonderheft 8/2016

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Summary

Background

In this study, we determined the frequency of migraine headache in iron-deficiency anemia (IDA) patients and whether it was related to anxiety, depression, and somatization.

Methods

We included 127 consecutive IDA patients into the study. All patients were asked validated questions about headache and migraine face-to-face. They were administered validated questionnaires for anxiety-depression The Hospital Anxiety and Depression Scale and somatization. The quality of life (QoL) disturbance associated with headache was marked on a 0–10 VAS.

Results

Of all IDA patients, 79.5 % defined headache at any time of their life. In addition, 36.2 % of all IDA patients defined the criteria for migraine. IDA patients with migraine were more frequently smokers and had significantly lower hemoglobin and mean corpuscular volume values (p values < 0.05). The IDA group with migraine had significantly higher mean anxiety score (p = 0.046) and headache-related QoL disturbance score (p = 0.021) than the IDA group without migraine. Migraine patients with aura had lower hemoglobin values (p = 0.02), higher depression scores (p = 0.005), and higher migraine-related QoL disturbance scores than others.

Conclusions

IDA patients have a high frequency of migraine headache. The presence of anxiety and depression have great influence on the presence of migraine in IDA patients.
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Metadaten
Titel
Is iron-deficiency anemia associated with migraine? Is there a role for anxiety and depression?
verfasst von
Prof. Dr. Gülsüm Emel Pamuk, MD
Mehmet Şerif Top, MD
Mehmet Şevki Uyanık, MD
Hilal Köker, MD
Mustafa Akker, MD
Recep Ak, MD
Ömer Atalay Yürekli, MD
Yahya Çelik, MD
Publikationsdatum
01.12.2016
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe Sonderheft 8/2016
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-015-0740-8

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