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01.06.2016 | case report | Ausgabe 2/2016

memo - Magazine of European Medical Oncology 2/2016

Intravascular large B‑cell lymphoma

A rare and potentially reversible cause of cerebral stroke

Zeitschrift:
memo - Magazine of European Medical Oncology > Ausgabe 2/2016
Autoren:
MD Silvia Hofer, MD Manfred Kessler, MD Jeanne Godau, MD Daniela Weiler, MD Karl Frontzek, MD Elisabeth Jane Rushing, MD Stefan Aebi
Wichtige Hinweise
S. Hofer and M. Kessler contributed equally to the manuscript.

Abstract

Intravascular lymphoma (IVL), a rare, extranodal form of non-Hodgkin lymphoma (NHL), can cause infarcts by occluding small arteries of the brain. Owing to its heterogeneous clinical manifestations and unfavorable prognosis, the diagnosis is often made postmortem. Patients can present with a range of motor or sensory deficits, rapid cognitive impairment, aphasia or signs of myelitis, often with nonspecific radiographic findings.Timely recognition of a treatable disease is essential to prevent permanent neurocognitive defects. We present a case who could be treated successfully with chemotherapy.

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