nach oben

Erschienen in:

01.02.2017 | main topic

Imaging of Paget’s disease of bone

verfasst von: Naomi Winn, MBBS, FRCR, BMedSci, Radhesh Lalam, MBBS, MRCS, FRCR, Victor Cassar-Pullicino, LRCP, MRCS, DMRD, MD, FRCR, FFSEM (UK), FFSEM (RCSI)

Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 1-2/2017

Einloggen, um Zugang zu erhalten

Summary

Paget’s disease of bone is a disorder of bone remodelling, leading to changes in the architecture and overall appearance of the bone. The disorder may be monostotic or polyostotic and affect any bone in the body, although most commonly it involves the spine, pelvis, skull and femur. This article explores the different imaging modalities used in the assessment of Paget’s disease of bone in its different phases. The relative merits of each imaging modality is discussed with illustrative examples, in particular with respect to radiographs, nuclear medicine bone scan, computed tomography (CT) and magnetic resonance imaging (MRI).

Vorheriger Artikel Epidemiology and pathology of Paget’s disease of bone – a review

Nächster Artikel Diagnosis and treatment of Paget’s disease of bone

Paget J. On a form of chronic inflammation of bones (osteitis deformans ). Med Chir Trans. 1877;60:37–64.CrossRefPubMedPubMedCentral

Resnick D. Paget disease of bone: Current status and a look back to 1943 and earlier. Am J Roentgenol. 1987;150(2):249–56.CrossRef

Cundy T. Is Paget’s disease of bone disappearing ? Skeletal Radiol. 2006;35:350–1.CrossRefPubMed

Guyer PB. Paget’s disease of bone : the anatomical distribution. Metab Bone Dis Relat Res. 1981;3(4–5):239–41.CrossRefPubMed

Ansari S, Bonar F, Stalley P, Brown W. Paget’s sarcoma of the patella. Skeletal Radiol. 2015;44:1057–63.CrossRefPubMed

Pratt H, Sampson M. Paget’s disease of bone presenting as chest pain and shoulder immobility. Clin Radiol. 2005;60:407–9.CrossRefPubMed

Al-rashid M, Ramkumar DB, Raskin K, Schwab J, Hornicek F, Santiago A, et al. Paget disease of bone. Orthop Clin North Am. 2015;46(4):577–85.CrossRefPubMed

Wilgram JW. Radiographical and pathological assessment of the activity of Paget’s disease of bone. Clin Orthop Relat Res. 1977;127:43–54.

Schubert F, Siddle KJ, et al. Diaphyseal Paget’s disease : an unusual finding in the tibia. Clin Radiol. 1984;35:71–4.CrossRefPubMed

10.

Dell’Atti C, Cassar-Pullicino VN, Lalam RK, Tins BJ, Tyrrell P. The spine in Paget’s disease. Skeletal Radiol. 2007;36:609–26.CrossRefPubMedPubMedCentral

11.

Smith R. Paget’s disease of bone: past and present. Bone. 1999;24(5):1S–2S.CrossRefPubMed

12.

Tehranzadeh J, Fung Y, Donohue M, Anavim A, Pribram HW. Computed tomography of Paget disease of the skull versus fibrous dysplasia. Skeletal Radiol. 1998;27:664–72.CrossRefPubMed

13.

Guanabens N, Rotes D, Holgado S, Gobbo M, Descalzo M, Gorordo J, et al. Implications of a new radiological approach for the assessment of Paget disease. Calcif Tissue Int. 2012;91:409–15.CrossRefPubMed

14.

Love C, Din AS, Tomas MB, Kalapparambath TP, Palestro CJ. Radionuclide bone imaging: an illustrative review. Radiographics. 2003;23(2):341–58.CrossRefPubMed

15.

Beaudouin C, Dohan A, Nasrallah T, Parlier C, Touraine S, Ea K, et al. Atypical vertebral Paget’s disease. Skeletal Radiol. 2014;43:991–5.CrossRefPubMed

16.

Whitten CR, Saifuddin A. Pictorial review MRI of Paget’s disease of bone. Clin Radiol. 2003;58:763–9.CrossRefPubMed

17.

Boutin RD, Spitz DJ, Newman JS, Lenchik L, Steinbach LS. Complications in Paget disease at MR imaging. Radiology. 1998;209(3):641–51.CrossRefPubMed

18.

Vande Berg BC, Malghem J, Lecouvet FE, Maldague B. Magnetic resonance appearance of uncomplicated Paget’s disease of bone. Semin Musculoskelet Radiol. 2001;5(1):69–78.CrossRefPubMed

19.

Libicher M, Kasperk C, Daniels-Wredenhagen M, Heye T, Kauczoe H, Nawroth P, et al. Dynamic contrast-enhanced MRI for monitoring bisphosphonate therapy in Paget’s disease of bone. Skeletal Radiol. 2013;42:225–30.CrossRefPubMed

20.

Cook G, Maisey M, Fogelman I. Fluorine-18-FDG PET in Paget’ s disease of bone. J Nucl Med. 1997;38:1495–7.PubMed

21.

Woo J‑H, Kim S, Choi SJ, Lee YH, Ji JD, Song GG. Diagnosis of Paget’s disease of the pelvis using F‑18 FDG PET/CT. Int J Rheum Dis. 2010;13(4):e51–e54.CrossRefPubMed

22.

Park ET, Kim S. Radiography, Bone scan, and F‑18 FDG PET/CT imaging findings in a patient with Paget’s disease. Nucl Med Mol Imaging. 2010;44(1):87–9.CrossRefPubMedPubMedCentral

23.

Lin FI, Rao JE, Mittra ES, Nallapareddy K, Chengapa A, Dick DW, et al. Prospective comparison of combined 18 F-FDG and 18 F-NaF PET/CT vs. 18 F-FDG PET/CT imaging for detection of malignancy. Eur J Nucl Med Mol Imaging. 2012;39(2):262–70.CrossRefPubMed

24.

Lander PH, Hadjipavlou AG. Paget disease with contraction of long bones. Radiol Radiol Soc N Am. 1986;159(2):471–2.

25.

MacGowan J, Pringle J, Morris VH, Stamp T. Gross vertebral collapse associated with long-term disodium etidronate treatment for pelvic Paget’s disease. Skeletal Radiol. 2000;29:279–82.CrossRefPubMed

26.

Isasi C, Sanz J, Hijos M, Vaquero M, Saucedo G, Andreu L. Successful treatment of optic neuropathy in osteitis deformans. Rheumatology. 2002;41:948–50.CrossRefPubMed

27.

Bone HG. Nonmalignant complications of Paget’s disease. J Bone Miner Res. 2006;21(Suppl 2):P64–P68.CrossRefPubMed

28.

Dizon G, Ritchie A, Myskow M. Case report: benign giant cell tumour associated with Paget’s disease of bone. Clin Radiol. 1995;50:269–71.CrossRef

29.

Hoch B, Hermann G, Klein MJ, Abdelwahab I, Springfield D. Giant cell tumor complicating Paget disease of long bone. Skeletal Radiol. 2007;36:973–8.CrossRefPubMed

30.

Brandolini F, Bacchini P, Moscato M, Bertoni F. Chondrosarcoma as a complicating factor in Paget’s disease of bone. Skeletal Radiol. 1997;26:497–500.CrossRefPubMed

31.

Theodorou DJ, Theodorou SJ, Kakitsubata Y. Imaging of Paget disease of bone and its musculoskeletal complications: review. Am J Roentgenol. 2011;196:64–75.CrossRef

32.

Gamage N, Kashima T, Mcnally M, Gibbons C, Smith R, Ostlere S, et al. Giant-cell-rich pseudotumour in Paget’s disease. Skeletal Radiol. 2013;42:595–9.CrossRefPubMed

33.

Mcnairn JDK, Damron TA, Landas SK, Ambrose JL. Benign tumefactive soft tissue extension from Paget’s disease of bone simulating malignancy. Skeletal Radiol. 2001;30:157–60.CrossRefPubMed

34.

Sundaram M, Khanna G, El-khoury GY. T1-weighted MR imaging for distinguishing large osteolysis of Paget’s disease from sarcomatous degeneration. Skeletal Radiol. 2001;30(7):378–83.CrossRefPubMed

35.

Hansen MF, Seton M, Merchant A. Osteosarcoma in Paget’s disease of bone. J Bone Miner Res. 2006;21(Suppl 2):P58–63.CrossRefPubMed

36.

Rendina D, Mossetti G, Soscia E, Sirignano C, Insabato L, Viceconti R, et al. Giant cell tumor and Paget’s disease of bone in one family: geographic clustering. Clin Orthop Relat Res. 2004;421:218–24.CrossRef

37.

Yu T, Squires F, Mammone J, DiMarcangelo M. Lymphoma arising in Paget’s disease. Skeletal Radiol. 1997;26(12):729–31.CrossRefPubMed

38.

Fenton P, Resnick D. Metastases to bone affected by Paget’s disease. A report of three cases. Int Orthop. 1991;15(4):397–9.CrossRefPubMed

39.

Vuillemin-bodaghi V, Parlier-cuau C, Cywiner-golenzer C. Multifocal osteogenic sarcoma in Paget’s disease. Skeletal Radiol. 2000;29(6):349–53.

40.

Tins BJ, Davies AM, Mangham DC. MR imaging of pseudosarcoma in Paget’s disease of bone: a report of two cases. Skeletal Radiol. 2001;30:161–5.CrossRefPubMed

41.

Mansour R, Nanni M, Muthukumar T, Butt S, Cassar-Pullicino VN. Subperiosteal ganglion associated with Paget s disease of bone. Skeletal Radiol. 2005;34:419–23.CrossRefPubMed

Titel: Imaging of Paget’s disease of bone
verfasst von: Naomi Winn, MBBS, FRCR, BMedSci
Radhesh Lalam, MBBS, MRCS, FRCR
Victor Cassar-Pullicino, LRCP, MRCS, DMRD, MD, FRCR, FFSEM (UK), FFSEM (RCSI)
Publikationsdatum: 01.02.2017
Verlag: Springer Vienna
Erschienen in: Wiener Medizinische Wochenschrift / Ausgabe 1-2/2017
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI: https://doi.org/10.1007/s10354-016-0517-3

Springer Medizin Österreich

Summary

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 1-2/2017

Epidemiology and pathology of Paget’s disease of bone – a review

Diagnosis and treatment of Paget’s disease of bone

Editorial: Paget’s disease of bone

Tumorstammzellen als therapeutisches Ziel der Tumortherapie von morgen

Leitlinie zur Palliativen Sedierungstherapie (Langversion)