nach oben

vorheriger Artikel In vitro activity of linezolid alone and combin...

nächster Artikel Pregnancy-related listeriosis: frequency and ge...

Tipp

Hydrogen peroxide (H₂O₂): a review of its use in surgery

Zeitschrift:: Wiener Medizinische Wochenschrift > Ausgabe 9-10/2019

Autoren:: Michael Vincent Urban, Univ.-Prof. Dr. Thomas Rath, MBA, FEBOPRAS Univ.-Prof. Dr. Christine Radtke

Summary

Hydrogen peroxide has been used in medicine for more than 100 years. It is known in surgery as a highly useful irrigation solution by virtue of both its hemostatic and its antimicrobial effects. Due to its possible negative effect on wound healing and its cytotoxic effect in higher concentrations, there are concerns about the safety of its use. The objective of this paper is to review the safety and beneficial effects of hydrogen peroxide.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Jetzt einloggen Kostenlos registrieren

Sie möchten Zugang zu diesem Inhalt erhalten? Dann informieren Sie sich jetzt über unsere Produkte:

Abo für kostenpflichtige Inhalte

Jetzt informieren

Marshall MV, Cancro LP, Fischman SL. Hydrogen peroxide: a review of its use in dentistry. J Peridontol. 1995;66(9):786–96. CrossRef

Drosou A, Falabella A, Kirsner RS. Antiseptics on wounds: an area of controversy. Wounds. 2013;15(5):149–66.

McDonnell G, Russel AD. Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev. 1999;12(1):147–79. CrossRef

Mohammadi AA, Seyed Jafari SM, Kiasat M, Pakyari MR, Ahrari I. Efficacy of debridement and wound cleansing with 2 % hydrogen peroxide on graft take in the chronic-colonized burn wounds; a randomized controlled clinical trial. Burns. 2013;39:1131–6. CrossRef

Hankin FM, Campbell SE, Goldstein SA, Matthews LS. Hydrogen peroxide as a topical hemostatic agent. Clin Orthop Relat Res. 1984;186:244–8.

Potyondy L, Lottenberg L, Anderson J, Mozingo DW. The use of hydrogen peroxide for achieving dermal hemostasis after burn excision in a patient with platelet dysfunction. J Burn Care Res. 2006;27(1):99–101. CrossRef

Schumb WC, Satterfield CN, Wentworth RL. Hydrogen peroxide. New York: Reinhold Publishing Corp; 1955. pp. 5–21.

Urschel H, McNamara J, Aslami A. Effects of hydrogen peroxide on arteriosclerosis. Surgery. 1968;63:21.

Jacques LB, Bell HJ. The reduction of hydrogen peroxide by fibrin. Can J Res. 1946;24:79–83. CrossRef

10.

Pratico D, Iuliano L, Ghiselli A, Alessandri C, Violi F. Hydrogen peroxide as trigger of platelet aggregation. Hemostasis. 1991;21(3):169–74.

11.

Pratico D, Iuliano L, Pulcinelli FM, Bonavita MS, Gazzaniga PP, Violi F. Hydrogen peroxide triggers activation of human platelets selectively exposed to nonaggregating concentrations of arachidonic acid and collagen. J Lab Clin Med. 1992;119(4):364–70. PubMed

12.

Singer AJ, Clark RA. Cutaneous wound healing. N Engl J Med. 1999;341:738–46. CrossRef

13.

Wasserbauer S, Perez-Meza D, Chao R. Hydrogen peroxide and wound healing: a theoretical and practical review for hair transplant surgeons. Dermatol Surg. 2008;34:745–50. PubMed

14.

Cho M, Hunt TK, Hussain MZ. Hydrogen peroxide stimulates macrophage vascular endothelial growth factor release. Am J Physiol Heart Circ Physiol. 2001;280:H2357–H63. CrossRef

15.

Barcellos-Hoff MH, Dix TA. Redox-mediated activation of latent transforming growth factor-beta 1. Mol Endocrinol. 1996;10(9):1077–83. PubMed

16.

Park SK, Kim J, Seomun Y, Choi J, Kim DH, Han IO, Lee EH, Chung SK, Joo CK. Hydrogen peroxide is a novel inducer of connective tissue growth factor. Biochem Biophys Res Commun. 2001;284(4):966–71. CrossRef

17.

Garcia-Trevijano ER, Iraburu MJ, Fontana L, Domínguez-Rosales JA, Auster A, Covarrubias-Pinedo A, Rojkind M. Transforming growth factor beta 1 induces the expression of alpha 1(I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta-dependent mechanism in rat hepatic stellate cells. Hepatology. 1999;29:960. CrossRef

18.

Chung LY, Schmidt RJ, Andrews AM, Turner TD. A study of hydrogen peroxide generation by, and antioxidant activity of, Granuflex hydrocolloid granules and some other hydrogel/hydrocolloid wound management materials. Br J Dermatol. 1993;129:145–53. CrossRef

19.

O’Toole EA, Goel M, Woodley DT. Hydrogen peroxide inhibits human keratinocyte migration. Dermatol Surg. 1996;22:525–9. CrossRef

20.

Geiser T, Ishigaki M, van Leer C, Matthay MA, Broaddus VC. H2O2 inhibits alveolar epithelial wound repair in vitro by induction of apoptosis. Am J Physiol Lung Cell Mol Physiol. 2004;287:L448–L53. CrossRef

21.

Wilgus TA, Bergdall VK, Dipietro LA, Oberyszyn TM. Hydrogen peroxide disrupts scarless fetal wound repair. Wound Repair Regen. 2005;13:513–9. CrossRef

22.

Tur E, Bolton L, Constantine BE. Topical hydrogen peroxide treatment of ischemic ulcers in the guinea pig: blood recruitment in multiple skin sites. J Am Acad Dermatol. 1995;33(1):217–21. CrossRef

23.

Pritchett S, Green D, Rossos P. Accidental ingestion of 35 % hydrogen peroxide. Can J Gastroenterol. 2007;21(10):665–7. CrossRef

24.

Watt BE, Proudfoot AT, Vale JA. Hydrogen peroxide poisoning. Toxicol Rev. 2004;23(1):51–7. CrossRef

25.

Henry MC, Wheeler J, Mofenson HC, Caraccio TR, Marsh M, Comer GM, Singer AJ. Hydrogen peroxide 3 % exposures. J Toxicol Clin Toxicol. 1996;34(3):323–7. CrossRef

26.

Russell AD. Bacterial spores and chemical sporicidal agents. Clin Microbiol Rev. 1990;3(2):99–119. CrossRef

27.

Jaimes EA, Sweeney C, Raij L. Effects of the reactive oxygen species hydrogen peroxide and hypochlorite on endothelial nitric oxide production. Hypertension. 2001;38:877–83. CrossRef

28.

Krötz F, Sohn HY, Pohl U. Reactive oxygen species: players in the platelet game. Arterioscler Thromb Vasc Biol. 2004;24:1988–96. CrossRef

Titel: Hydrogen peroxide (H2O2): a review of its use in surgery
Autoren:: Michael Vincent Urban
Univ.-Prof. Dr. Thomas Rath
MBA, FEBOPRAS Univ.-Prof. Dr. Christine Radtke
Publikationsdatum: 16.11.2017
DOI: https://doi.org/10.1007/s10354-017-0610-2
Verlag: Springer Vienna
Zeitschrift: Wiener Medizinische Wochenschrift
Ausgabe 9-10/2019
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X

Springer Medizin Österreich

Tipp

Weitere Artikel dieser Ausgabe durch Wischen aufrufen

Summary

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Sie möchten Zugang zu diesem Inhalt erhalten? Dann informieren Sie sich jetzt über unsere Produkte:

Abo für kostenpflichtige Inhalte

Weitere Artikel der Ausgabe 9-10/2019

Epidemiologic, clinical, and laboratory characteristics of childhood brucellosis

In vitro activity of linezolid alone and combined with other antibiotics against clinical enterococcal isolates

Pregnancy-related listeriosis: frequency and genotypic characteristics of L. monocytogenes from human specimens in Kerman, Iran

Nerve grafting for peripheral nerve injuries with extended defect sizes

Impfen ist nicht nur Kindersache!