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How reliable is laser ablation depth readout when planning corneal refractive surgery?

  • 01.06.2013
  • original article
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Summary

Purpose To analyze the amount of correlation between the intended ablation depth (IAD), as given by the ablation depth readout of the MEL 80 Excimer Laser and the clinically observed ablation depth (OAD), as measured by noncontact optical low-coherence reflecto-metry-pachymetry (OLCR-pachymetry) after Laser in situ keratomileusis (LASIK) and which pre- or perioperative factors would determine the relative amount of the preset laser ablation depth.

Methods

Retrospective, non-comparative, interventional study including 234 spherical or spherocylindrical Caucasian myopic eyes. Only eyes with a pre- and postoperative cylinder < 1.0 diopters and a postoperative re-fractive spherical equivalent (mean refractive spherical equivalent (MRSE)) within ± 0.5 diopters of plano with a minimum of 2 months follow-up were included to reduce unknown bias.

Results

Eleven measurable variables (IAD, corneal thickness (CT), optical zone diameter (OZ), intraoperative flap thickness (FT), intraocular pressure (IOP), sphere, cylinder, mean keratometry (K mean), year of surgery, gender, and age) which might have influenced the difference between IAD and OAD (IAD −OAD = DIR) were evaluated. Four variables with the most significant influence on DIR were chosen by calculating a full general regression model initially and a best-subset regression model thereafter. These four statistical significant variables are: IAD (p = 0.000001), OZ (p = 0.0006), CT (p = 0.0007), and FT (p = 0.0489). A correlation analysis of DIR also showed that right and left eyes are correlated to each other (r = 0.4, p < 0.0001)

Conclusions

The most important factor explaining the variance of DIR seems to be IAD (16 %), OZ (4.4 %), CT (2.1 %), and FT (2.2 %). Overall, 24.7 % of variance may be explained with these four variables of the best-subset analysis in a general regression model.
Die Reliabilität der angezeigten Laserablations Tiefe bei der Planung refraktiv-Hornhautchirurgischer Eingriffe
Titel
How reliable is laser ablation depth readout when planning corneal refractive surgery?
Verfasst von
Orang Seyeddain, MD
Prim. Univ.-Prof. Dr. Günther Grabner, MD
Wolfgang Hitzl, PhD
Josef Ruckhofer, MD
Alois Dexl, MD, Msc
Alexander Bachernegg, MD
Publikationsdatum
01.06.2013
Verlag
Springer Vienna
Erschienen in
Spektrum der Augenheilkunde / Ausgabe 3/2013
Print ISSN: 0930-4282
Elektronische ISSN: 1613-7523
DOI
https://doi.org/10.1007/s00717-013-0167-4
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