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Erschienen in: Wiener klinische Wochenschrift 15-16/2014

01.08.2014 | original article

Evaluation of epicardial fat tissue thickness in patients with hyperthyroidism

verfasst von: MD Assist. Prof. Dr. Emine Binnetoğlu, Assist. Prof. Dr. Mehmet Asik, Assist. Prof. Dr. Burak Altun, Assist. Prof. Dr. Hacer Sen, Assist. Prof. Dr. Emine Gazi, Assist. Prof. Dr. Gökhan Erbağ, Assist. Prof. Dr. Fahri Günes, Assist. Dr. Yıldız Garip Bilen, Assist. Prof. Dr. Ahmet Temiz, Assist. Prof. Dr. Ahmet Barutçu, Assist. Prof. Dr. Adem Bekler

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 15-16/2014

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Summary

Background

Thyroid hormones have several effects on the cardiovascular system, and recent studies have found that thyroid disorders affect coronary intima-media thickness (CIMT) in particular. Despite increased CIMT in patients with hyperthyroidism, the extent of the relationship between CIMT and epicardial fat thickness (EFT) in those patients is unknown. Furthermore, there is no report evaluating the relationship between EFT and overt hyperthyroidism (OH) in the literature. In this study, we aim to evaluate the effectiveness of EFT in predicting atherosclerosis as well as CIMT in patients with OH.

Methods

A total of 30 newly diagnosed, untreated overt hyperthyroid patients and 44 control subjects were included in the study. EFT was measured using a commercially available echocardiography machine (VIVID 7; General Electric Medical Systems, Norway) with a 2.5-MHz probe. The echo-free space between the visceral and parietal pericardium on the anterior wall of the right ventricle was diagnosed as EFT. A linear-array imaging probe of the same echocardiography probe was used to evaluate the CIMT of the right common carotid artery.

Results

The hyperthyroid patients had a significantly greater EFT (mean: 4.31 ± 1.12 mm) than the healthy subjects (mean: 3.11 ± 0.84 mm; p < 0.001). CIMT was also significantly greater in the hyperthyroid patients (mean: 0.62 ± 0.17 mm) than in the healthy subjects (mean: 0.50 ± 0.11 mm; p < 0.01).

Conclusion

In conclusion, the present study shows that mean EFT and CIMT were significantly higher in OH patients, irrespective of confounding factors such as hypertension.
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Metadaten
Titel
Evaluation of epicardial fat tissue thickness in patients with hyperthyroidism
verfasst von
MD Assist. Prof. Dr. Emine Binnetoğlu
Assist. Prof. Dr. Mehmet Asik
Assist. Prof. Dr. Burak Altun
Assist. Prof. Dr. Hacer Sen
Assist. Prof. Dr. Emine Gazi
Assist. Prof. Dr. Gökhan Erbağ
Assist. Prof. Dr. Fahri Günes
Assist. Dr. Yıldız Garip Bilen
Assist. Prof. Dr. Ahmet Temiz
Assist. Prof. Dr. Ahmet Barutçu
Assist. Prof. Dr. Adem Bekler
Publikationsdatum
01.08.2014
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 15-16/2014
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-014-0570-0