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Erschienen in: Wiener klinische Wochenschrift 21-22/2015

01.11.2015 | original article

Evaluation of electrocardiographic parameters in patients with diabetes insipidus

verfasst von: Assoc. Prof. Ferhat Deniz, Assoc. Prof. Alper Kepez, MD Seyit Ahmet Ay, Prof. Okan Ergogan, MD Kamil Baskoy, Mustafa Nuri Guncıkan, MD Zekeriya Dogan, Assoc. Prof. Arif Yonem

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 21-22/2015

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Summary

Background

There is limited data regarding the effect of altered serum osmolality on cardiac electrical activity. The aim of the present study is to evaluate the electrocardiographic (ECG) effects of diabetes insipidus (DI) and any related hyperosmolality in a population of young patients with DI and without any known cardiovascular disease or risk factors.

Methods

Twelve-lead ECG’s of 44 consecutive untreated young male patients (age: 21.8 ± 2.9 years) who had been referred to endocrinology clinic and diagnosed as DI based on water deprivation test were retrospectively evaluated. A total of 30 age-matched (21.9 ± 2.4 years) healthy males were selected as control group and ECG’s of these controls were obtained for comparison with ECG’s of DI patients. All ECG parameters were measured and compared.

Results

Duration of QRS complex was significantly shorter in patients with DI compared with controls (85.2 ± 12.0 vs. 94.0 ± 10.6 ms, p: 0.001). P wave dispersion (PWD) of patients with DI was significantly higher compared with controls (31.9 ± 9.9 vs. 26.5 ± 10.6 ms, p: 0.03) and it was significantly correlated with serum osmolality and serum sodium level (r = − 0.36, p: 0.02 and r: − 0.35, p: 0.02, respectively).

Conclusions

DI patients without any cardiovascular disease or risk factors displayed significantly shorter QRS duration and increased p wave dispersion compared with controls.
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Metadaten
Titel
Evaluation of electrocardiographic parameters in patients with diabetes insipidus
verfasst von
Assoc. Prof. Ferhat Deniz
Assoc. Prof. Alper Kepez
MD Seyit Ahmet Ay
Prof. Okan Ergogan
MD Kamil Baskoy
Mustafa Nuri Guncıkan
MD Zekeriya Dogan
Assoc. Prof. Arif Yonem
Publikationsdatum
01.11.2015
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 21-22/2015
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-015-0874-8