Skip to main content


Weitere Artikel dieser Ausgabe durch Wischen aufrufen

01.11.2015 | original article | Ausgabe 21-22/2015

Wiener klinische Wochenschrift 21-22/2015

Evaluation of electrocardiographic parameters in patients with diabetes insipidus

Wiener klinische Wochenschrift > Ausgabe 21-22/2015
Assoc. Prof. Ferhat Deniz, Assoc. Prof. Alper Kepez, MD Seyit Ahmet Ay, Prof. Okan Ergogan, MD Kamil Baskoy, Mustafa Nuri Guncıkan, MD Zekeriya Dogan, Assoc. Prof. Arif Yonem



There is limited data regarding the effect of altered serum osmolality on cardiac electrical activity. The aim of the present study is to evaluate the electrocardiographic (ECG) effects of diabetes insipidus (DI) and any related hyperosmolality in a population of young patients with DI and without any known cardiovascular disease or risk factors.


Twelve-lead ECG’s of 44 consecutive untreated young male patients (age: 21.8 ± 2.9 years) who had been referred to endocrinology clinic and diagnosed as DI based on water deprivation test were retrospectively evaluated. A total of 30 age-matched (21.9 ± 2.4 years) healthy males were selected as control group and ECG’s of these controls were obtained for comparison with ECG’s of DI patients. All ECG parameters were measured and compared.


Duration of QRS complex was significantly shorter in patients with DI compared with controls (85.2 ± 12.0 vs. 94.0 ± 10.6 ms, p: 0.001). P wave dispersion (PWD) of patients with DI was significantly higher compared with controls (31.9 ± 9.9 vs. 26.5 ± 10.6 ms, p: 0.03) and it was significantly correlated with serum osmolality and serum sodium level (r = − 0.36, p: 0.02 and r: − 0.35, p: 0.02, respectively).


DI patients without any cardiovascular disease or risk factors displayed significantly shorter QRS duration and increased p wave dispersion compared with controls.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Sie möchten Zugang zu diesem Inhalt erhalten? Dann informieren Sie sich jetzt über unsere Produkte:

Abo für kostenpflichtige Inhalte

Über diesen Artikel

Weitere Artikel der Ausgabe 21-22/2015

Wiener klinische Wochenschrift 21-22/2015 Zur Ausgabe

MUW researcher of the month

MUW researcher of the month