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01.07.2012 | original article

Evaluation of atrial electromechanical delay and left atrial mechanical function in patients with obstructive sleep apnea

Cardiac involvement in patients with OSA

verfasst von: Turgut Karabag, MD, Prof. Mustafa Aydin, MD, Remzi Altin, MD, Sait M. Dogan, MD, Cem Cil, MD, Cagatay Buyukuysal, MSc, Muhammet R. Sayin, MD

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 13-14/2012

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Summary

Objective

The aim of this study was to evaluate atrial electromechanical delay measured by tissue Doppler imaging and left atrial mechanical function in patients with obstructive sleep apnea (OSA).

Materials and methods

Fourty-seven moderate-to-severe OSA patients who were newly diagnosed by polysomnography (Apnea-hypopnea index ³ 15 events/h, 32 males, mean age 49.4 ± 11.5) and 30 patients who had no OSA in polysomnography (Apnea-hypopnea index < 5 events/h, 21 males, mean age 45.4 ± 9.1) were included in the study. Using tissue Doppler, diastolic functions, atrial electromechanical coupling were measured from the lateral mitral, septal, and tricuspid annulus. İnter, intra, and left atrial electromechanical delay were calculated (lateral-tricuspid, septum-tricuspid, lateral-septal). Left atrial volumes (maximal, minimal, and presystolic) were measured by the method of discs in the apical four-chamber view and were indexed to body surface area. Mechanical function parameters of the left atrium were also calculated.

Results

Interatrial, intraatrial, and left atrial electromechanical delays were significantly higher in the OSA group compared to the control group. Passive emptying fraction was significantly decreased, volume at the beginning of atrial systole and active emptying volume were significantly increased in OSA patients compared to the controls. The apnea-hypopnea index was significantly associated with interatrial and intraatrial electromechanical delay, passive emptying fraction, and conduit volume.

Conclusions

Electromechanical delay was markedly prolonged and left atrial electromechanical function was impaired in untreated OSA patients. These impairments worsen with increasing severity of OSA.

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Titel: Evaluation of atrial electromechanical delay and left atrial mechanical function in patients with obstructive sleep apnea
Cardiac involvement in patients with OSA
verfasst von: Turgut Karabag, MD
Prof. Mustafa Aydin, MD
Remzi Altin, MD
Sait M. Dogan, MD
Cem Cil, MD
Cagatay Buyukuysal, MSc
Muhammet R. Sayin, MD
Publikationsdatum: 01.07.2012
Verlag: Springer Vienna
Erschienen in: Wiener klinische Wochenschrift / Ausgabe 13-14/2012
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI: https://doi.org/10.1007/s00508-012-0197-y

Springer Medizin Österreich

Summary

Objective

Materials and methods

Results

Conclusions

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