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Erschienen in: Wiener klinische Wochenschrift 11-12/2015

01.06.2015 | original article

Estimation of incidence, prevalence, and age-at-diagnosis of myasthenia gravis among adults by hospital discharge records

verfasst von: Anett Foldvari, Nora Kovacs, Valeria Sipos, Gabriella Merth, Ferenc Vincze, MD Maria Szucs, MD, PhD Janos Sandor

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 11-12/2015

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Summary

Background

The Hungarian Health Insurance Fund, using appropriate information technology, covers all of the secondary care of the country and maintains a database of Hospital Discharge Records (HDR). Our study aimed to determine the incidence, average age-at-diagnosis (AaD), and prevalence of myasthenia gravis (MG) among adults and the regional heterogeneity of these measures to assess the potential usefulness of HDRs for monitoring.

Methods

The nationwide database of 336,679 HDRs from 2004 to 2009 was analyzed. The incidence and prevalence were determined for adults in 2007. Patients with MG code in 2007, 2008, and 2009 but without that in 2004–2006 were defined as incident. Distribution of AaD was described for these cases. Patients with an MG code in 2007, 2008, and 2009 were defined as prevalent in 2007. The heterogeneity of regional age-standardized indices was tested.

Results

The observed incidence and prevalence was 2.76/100,000 (men: 2.37/100,000; women: 3.11/100,000) and 17.42/100,000 (male: 13.08/100,000; female: 21.28/100,000), respectively. These estimates were within published ranges. The mean AaD was significantly higher for men than for women (63.60 vs. 51.92; p < 0.001). Significant regional heterogeneity was observed for all measures.

Conclusions

HDRs seem to be useful for developing MG indicators because they adequately estimate epidemiological parameters of MG occurrence.
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Metadaten
Titel
Estimation of incidence, prevalence, and age-at-diagnosis of myasthenia gravis among adults by hospital discharge records
verfasst von
Anett Foldvari
Nora Kovacs
Valeria Sipos
Gabriella Merth
Ferenc Vincze
MD Maria Szucs
MD, PhD Janos Sandor
Publikationsdatum
01.06.2015
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 11-12/2015
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-015-0796-5