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Erschienen in: Journal für Urologie und Urogynäkologie/Österreich 4/2022

22.11.2022 | Originalien

Das metastasierte Urothelkarzinom – leitlinienorientierte Therapie und neue Optionen

verfasst von: Univ.-Prof. Dr. med. Günter Niegisch, Gunhild von Amsberg, Marc Rehlinghaus, Camilla M. Grunewald, Margitta Retz

Erschienen in: Journal für Urologie und Urogynäkologie/Österreich | Ausgabe 4/2022

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Zusammenfassung

Durch die Zulassung immunonkologischer Therapien mit Immun-Checkpoint-Inhibitoren ist die Behandlung des metastasierten Urothelkarzinoms in allen Therapielinien komplexer geworden. So finden sich mittlerweile in der Erstlinientherapie neben der alleinigen klassischen Behandlung mit Platin-basierten Kombinationschemotherapien sowohl die Option einer alleinigen Immuntherapie als auch einer Immunerhaltungstherapie im Anschluss an die Chemotherapie. Bei der Therapiewahl sind neben dem Zulassungsstatus und der Leitlinienempfehlung immer auch patientenindividuelle Faktoren wie Komorbiditäten sowie die Patientenpräferenz zu berücksichtigen. Der folgende Artikel soll die aktuelle Datenlage zu verschiedenen Behandlungsoptionen in der Erstlinientherapie des metastasierten Urothelkarzinoms zusammenfassen und diese anhand eines Patientenbeispiels illustrieren.
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Metadaten
Titel
Das metastasierte Urothelkarzinom – leitlinienorientierte Therapie und neue Optionen
verfasst von
Univ.-Prof. Dr. med. Günter Niegisch
Gunhild von Amsberg
Marc Rehlinghaus
Camilla M. Grunewald
Margitta Retz
Publikationsdatum
22.11.2022
Verlag
Springer Vienna
Erschienen in
Journal für Urologie und Urogynäkologie/Österreich / Ausgabe 4/2022
Print ISSN: 1023-6090
Elektronische ISSN: 1680-9424
DOI
https://doi.org/10.1007/s41972-022-00181-x

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