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Erschienen in: Spektrum der Augenheilkunde 3/2014

01.06.2014 | case report

Congenital cataract with and without anterior granulomatous uveitis in twins: a case report

verfasst von: MD, PhD Karin Pekovits, MD, PhD Christoph Faschinger

Erschienen in: Spektrum der Augenheilkunde | Ausgabe 3/2014

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Summary

Background

Congenital cataract is the most common cause of treatable blindness in infants. Roughly, one-third of congenital cataracts are inherited and one-third are associated with congenital infections, metabolic disorders, chromosome abnormalities, or genetic syndromes, with the remainder of unclear cause. To prevent blindness or amblyopia, prompt diagnosis and treatment is mandatory.

Case presentation

We herein describe the cases of two male premature non-identical twins presenting congenital cataract and anterior granulomatous uveitis simultaneously. In both cases, conservative treatment could not control the intraocular inflammation. Common causes of granulomatous uveitis in newborn were excluded by extensive clinical and laboratory investigations performed in both mother and children. Lens aspiration resulted in prompt resolution of the uveitis in both cases.

Discussion

In the absence of any detectable infectious agent and the lack of a genetic disorder, systemic metabolic disease, or inherited syndrome, a phacogenic pathomechanism that provoked and further maintained the intraocular inflammatory reaction might be possible. This report underscores the importance that in some rare cases, lens extraction is the only way to control intraocular inflammation in presence of both anterior uveitis and cataract.
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Metadaten
Titel
Congenital cataract with and without anterior granulomatous uveitis in twins: a case report
verfasst von
MD, PhD Karin Pekovits
MD, PhD Christoph Faschinger
Publikationsdatum
01.06.2014
Verlag
Springer Vienna
Erschienen in
Spektrum der Augenheilkunde / Ausgabe 3/2014
Print ISSN: 0930-4282
Elektronische ISSN: 1613-7523
DOI
https://doi.org/10.1007/s00717-013-0194-1