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25.05.2022 | original article

Comparison between exercise therapy and non-hydrolyzed collagen (UC-II) in functionality and quality of life in women with knee osteoarthritis

A randomized controlled clinical trial

verfasst von: Érika Thatyana Nascimento Santana, Saulo da Cunha Machado, Viviane Nascimento Brandão Lima, Valter Joviniano DeSantana Filho, Leonardo Yung dos Santos Maciel, Jader Pereira de Farias Neto, Henrique Douglas Melo Coutinho, Natália Martins, Walderi Monteiro da Silva Júnior, Lucindo J. Quintans Júnior

Erschienen in: Wiener klinische Wochenschrift

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Summary

Background

Knee osteoarthritis (OA) is characterized by a progressive degeneration of cartilage and menisci, leading to pain and locomotor disability. Here, we aimed to assess the effect of an exercise protocol and the oral use of non-hydrolyzed collagen (UC-II) on the functionality and quality of life of women with knee OA.

Material and methods

Individuals were divided into three groups (CG [control group]; MG [medication group]; EG [exercise group]). In the CG there was no intervention, while MG received an oral dose (1 capsule/day) of UC-II and the EG held 12 sessions of an exercise protocol.

Results

In the functionality tests (6-min walk test, 6MWT and timed up and go test [TUG]) the EG (p < 0.001/p = 0.020) and MG (p = 0.010/p = 0.010) revealed a significant improvement when compared to the CG. In the analysis of quality of life by WOMAC, a significant improvement was found only in the EG (p = 0.030) when compared to the CG; the same happened in the stiffness domain (EG, p = 0.010), despite in the pain domain, both the EG (p < 0.001) and the MG (p = 0.060) were better than the CG.

Conclusion

Data obtained here reveal that an exercise protocol and UC-II have similar effects for functionality, despite exercise being superior in promoting the quality of life score.
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Metadaten
Titel
Comparison between exercise therapy and non-hydrolyzed collagen (UC-II) in functionality and quality of life in women with knee osteoarthritis
A randomized controlled clinical trial
verfasst von
Érika Thatyana Nascimento Santana
Saulo da Cunha Machado
Viviane Nascimento Brandão Lima
Valter Joviniano DeSantana Filho
Leonardo Yung dos Santos Maciel
Jader Pereira de Farias Neto
Henrique Douglas Melo Coutinho
Natália Martins
Walderi Monteiro da Silva Júnior
Lucindo J. Quintans Júnior
Publikationsdatum
25.05.2022
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-022-02037-8