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01.06.2015 | main topic | Ausgabe 11-12/2015

Wiener Medizinische Wochenschrift 11-12/2015

Clinical trials with herbal medicinal products in children: a literature analysis

Zeitschrift:
Wiener Medizinische Wochenschrift > Ausgabe 11-12/2015
Autoren:
Peter Marquardt, Karin Kaft, Prof. Dr. Karen Nieber

Abstract

Herbal medicinal products have been used since several decades for the health care of children. Nevertheless, well-controlled clinical studies with herbal medicinal products for children are rare. The authors’ objective therefore was to evaluate clinical trials with herbal medicinal products in children, based on a literature search in PubMed and Web of Science. A total of 133 trials were identified. 90 studies were randomized, 32.2 % were randomized and double-blinded. Most studies were performed in China, in the age group 6–12 years, and in children with respiratory diseases, most often herbal medicinal products with Hedera helix were tested. The analysis revealed that studies on herbal medicinal products were feasible in children. Although clinical trials have been found, this literature search have limitations and did not cover all studies performed. However, only few clinical trials of high quality were identified. Further studies therefore are urgently needed to support the good empirical findings.

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