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Erschienen in: Wiener Medizinische Wochenschrift 13-14/2019

16.01.2019 | main topic

Clinical melanoma characteristics and survival—a single-center retrospective study between 2000 and 2010

verfasst von: Dr. Valentin Feichtenschlager, Felix Weihsengruber, Leo Richter, Igor Vujic, Klemens Rappersberger, Christian Posch

Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 13-14/2019

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Summary

The aim of this study was to characterize clinical, histological, and outcome features of primary melanoma in 1329 patients managed at a single-center institution between 2000 and 2010. Parameters included age at diagnosis, sex, tumor location, histology, stage, Breslow thickness, and sentinel lymph node status among others. The mean age at diagnosis was 59.1 ± 16.7 years. Women were significantly younger than men when diagnosed (57.2 vs. 61.0 years; p < 0.001). Most melanomas (83%) were diagnosed on typically sun-exposed skin areas. Superficial spreading melanoma (39.5%) was the most frequent histological subtype. The median Breslow thickness was significantly higher for men compared to women (1.10 mm vs. 0.90 mm; p = 0.018). 38.3% of patients with positive and 12.9% of patients with negative sentinel biopsies progressed. Five-year survival analysis for a sub-cohort of 577 patients showed better 5‑year overall survival for woman compared to men (75.8% vs. 63.6%; p = 0.025). Our findings indicate differences in patient characteristics between men and women, and underscore the importance of early melanoma detection to prevent disease progression.
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Metadaten
Titel
Clinical melanoma characteristics and survival—a single-center retrospective study between 2000 and 2010
verfasst von
Dr. Valentin Feichtenschlager
Felix Weihsengruber
Leo Richter
Igor Vujic
Klemens Rappersberger
Christian Posch
Publikationsdatum
16.01.2019
Verlag
Springer Vienna
Erschienen in
Wiener Medizinische Wochenschrift / Ausgabe 13-14/2019
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI
https://doi.org/10.1007/s10354-018-0678-3

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