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Erschienen in: Wiener klinische Wochenschrift 17-18/2021

03.06.2021 | original article

Clinical and radiological characteristics of COVID‑19 patients without comorbidities

A single-center study

verfasst von: MD Saffet Ozturk, MD Esin Kurtulus Ozturk, MD Sibel Yildiz Kaya

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 17-18/2021

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Summary

Objective

To evaluate the clinical characteristics and detailed imaging features in coronavirus disease 2019 (COVID-19) patients without comorbidities.

Material and methods

This retrospective study included laboratory-confirmed and symptomatic COVID-19 patients without comorbid diseases who were admitted to our second level hospital between March 2020 and September 2020. We assessed the clinical, biochemical and imaging diagnostic parameters on admission. The patients were classified as non-severe and progress to severe group and then the initial parameters were compared.

Results

We enrolled 135 adult COVID-19 patients, 12 progressed to severe disease during hospitalization. Compared to the non-severe group, patients who progressed to severe were older (p < 0.001) and were more likely to manifest coughing (p = 0.011) and have higher lactate dehydrogenase (LDH) levels (p = 0.011). On chest computed tomography (CT) images, multilobar (p = 0.016), peripherally (p = 0.001) distributed mixed ground glass opacities and consolidation (p < 0.001), crazy paving (p = 0.007) and higher total CT severity score (p < 0.001) were significantly associated with severe disease.

Conclusion

Knowledge of the clinical and radiological parameters associated with disease severity might be useful to guide clinical decision-making for COVID-19 patients without comorbidities.
Literatur
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Zurück zum Zitat deJaegere TMH, Krdzalic J,Fasen BACM, Kwee RM (2020) Radiological Society of North America Chest CT Classification System for Reporting COVID-19 Pneumonia: Interobserver Variability and Correlation with Reverse-Transcription Polymerase Chain Reaction. Radiology: Cardiothoracic Imaging 2 (3):e200213 deJaegere TMH, Krdzalic J,Fasen BACM, Kwee RM (2020) Radiological Society of North America Chest CT Classification System for Reporting COVID-19 Pneumonia: Interobserver Variability and Correlation with Reverse-Transcription Polymerase Chain Reaction. Radiology: Cardiothoracic Imaging 2 (3):e200213
Metadaten
Titel
Clinical and radiological characteristics of COVID‑19 patients without comorbidities
A single-center study
verfasst von
MD Saffet Ozturk
MD Esin Kurtulus Ozturk
MD Sibel Yildiz Kaya
Publikationsdatum
03.06.2021
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 17-18/2021
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-021-01880-5