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Erschienen in: memo - Magazine of European Medical Oncology 4/2022

04.10.2022 | case report

Bilateral primary breast lymphoma in a pregnant woman: a case report and literature review

verfasst von: Hasan Cagri Yildirim, Arif Akyildiz, Rashad Ismayilov, MD, Nartan Demirok, Burhan Sami Benli, Deniz Can Guven, Serkan Akin, Suayib Yalcin, Ibrahim Barista

Erschienen in: memo - Magazine of European Medical Oncology | Ausgabe 4/2022

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Summary

Primary breast lymphoma (PBL) represents 0.04–1% of all breast malignancies and is extremely rare in pregnancy. PBL affects women much more often than men and tends to be unilateral. Diffuse large B‑cell lymphoma (DLBCL) is the most common histological subtype of PBL. Treatment options include chemotherapy, radiotherapy, immunotherapy, and surgery, but are not clearly defined. We reported herein a case of bilateral primary breast lymphoma in a 35-year-old pregnant woman. After the diagnosis of DLBCL, R‑CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) was started in the second trimester. Postpartum intrathecal methotrexate prophylaxis and adjuvant radiotherapy were applied and a complete response was obtained. Twelve months after the initial diagnosis, our patient remains alive and relapse-free.
Literatur
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Metadaten
Titel
Bilateral primary breast lymphoma in a pregnant woman: a case report and literature review
verfasst von
Hasan Cagri Yildirim
Arif Akyildiz
Rashad Ismayilov, MD
Nartan Demirok
Burhan Sami Benli
Deniz Can Guven
Serkan Akin
Suayib Yalcin
Ibrahim Barista
Publikationsdatum
04.10.2022
Verlag
Springer Vienna
Erschienen in
memo - Magazine of European Medical Oncology / Ausgabe 4/2022
Print ISSN: 1865-5041
Elektronische ISSN: 1865-5076
DOI
https://doi.org/10.1007/s12254-022-00843-4

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