Skip to main content
Registrieren
Springer Medizin Österreich
SUCHE
MENÜ 1 2 3 4
nach oben

Tipp

Weitere Artikel dieser Ausgabe durch Wischen aufrufen

Erschienen in: Wiener klinisches Magazin 4/2015

01.09.2015 | Chirurgie

Behandlung postoperativer Passagestörungen, Cholangitis und Pankreatitis

verfasst von: Dr. Dr. Tobias Schulze, Claus-Dieter Heidecke

Erschienen in: Wiener klinisches Magazin | Ausgabe 4/2015

Einloggen, um Zugang zu erhalten
share
TEILEN

Zusammenfassung

Trotz in den letzten Jahrzehnten deutlich rückläufiger Mortalitätszahlen bleiben große hepatopankreatobiliäre Eingriffe mit einer hohen Morbidität behaftet. Deregulierte Funktionszustände der Darmmotilität sowie Entzündungen und Infektionen im Bereich der operierten Organe haben daran einen beträchtlichen Anteil und tragen zu einer signifikanten Verlängerung der Krankenhausaufenthaltsdauer und zu einer deutlichen Steigerung des Ressourcenverbrauchs bei. Diese Übersichtsarbeit zeigt anhand der Auswertung von aktuellen Grundlagenarbeiten, klinischen Studien, Übersichtsarbeiten, Metaanalysen und Leilinien therapeutische Ansätze und Entwicklungen in der Behandlung der verzögerten Magenentleerung, des prolongierten postoperativen Ileus, der postoperativen Cholangitis und Pankreatitis auf.
Vorheriger Artikel Blutgerinnungsbeeinflussende Medikamente in der Thoraxchirurgie
Nächster Artikel Aktuell
Literatur
1.
Amini A, Patanwala AE, Maegawa FB et al (2012) Effect of epidural analgesia on postoperative complications following pancreaticoduodenectomy. Am J Surg 204:1000–1004 PubMedCrossRef
2.
Axelrod TM, Mendez BM, Abood GJ et al (2015) Peri-operative epidural may not be the preferred form of analgesia in select patients undergoing pancreaticoduodenectomy. J Surg Oncol 111:306–310 PubMedCrossRef
3.
Bakker OJ, van Santvoort HC, van Brunschot S et al (2012) Endoscopic transgastric vs surgical necrosectomy for infected necrotizing pancreatitis: a randomized trial. JAMA 307:1053–1061 PubMedCrossRef
4.
Balzano G, Zerbi A, Braga M et al (2008) Fast-track recovery programme after pancreatico- duodenectomy reduces delayed gastric emptying. Br J Surg 95:1387–1393 PubMedCrossRef
5.
Baradi H, Walsh RM, Henderson JM et al (2004) Postoperative jejunal feeding and outcome of pancreaticoduodenectomy. J Gastrointest Surg 8:428–433 PubMedCrossRef
6.
Beane JD, House MG, Miller A et al (2014) Optimal management of delayed gastric emptying after pancreatectomy: an analysis of 1,089 patients. Surgery 156:939–946 PubMedCrossRef
7.
Berberat PO, Friess H, Kleeff J et al (1999) Prevention and treatment of complications in pancreatic cancer surgery. Dig Surg 16:327–336 PubMedCrossRef
8.
Berberat PO, Ingold H, Gulbinas A et al (2007) Fast track – different implications in pancreatic surgery. J Gastrointest Surg 11:880–887 PubMedCrossRef
9.
10.
Braga M, Gianotti L, Gentilini O et al (2001) Early postoperative enteral nutrition improves gut oxygenation and reduces costs compared with total parenteral nutrition. Crit Care Med 29:242–248 PubMedCrossRef
11.
Burt M, Scott A, Williard WC et al (1996) Erythromycin stimulates gastric emptying after esophagectomy with gastric replacement: a randomized clinical trial. J Thorac Cardiovasc Surg 111:649–654 PubMedCrossRef
12.
Chuang JH, Lee SY, Chen WJ et al (2001) Changes in bacterial concentration in the liver correlate with that in the hepaticojejunostomy after bile duct reconstruction: implication in the pathogenesis of postoperative cholangitis. World J Surg 25:1512–1518 PubMedCrossRef
13.
Coolsen MM, van Dam RM, van der Wilt AA et al (2013) Systematic review and meta-analysis of enhanced recovery after pancreatic surgery with particular emphasis on pancreaticoduodenectomies. World J Surg 37:1909–1918 PubMedCrossRef
14.
De Bruin ML, Langendijk PN, Koopmans RP et al (2007) In-hospital cardiac arrest is associated with use of non-antiarrhythmic QTc-prolonging drugs. Br J Clin Pharmacol 63:216–223 PubMedCrossRefPubMedCentral
15.
di Sebastiano P, Festa L, De Bonis A et al (2011) A modified fast-track program for pancreatic surgery: a prospective single-center experience. Langenbecks Arch Surg 396:345–351 PubMedCrossRef
16.
Dong K, Yu XJ, Li B et al (2006) Advances in mechanisms of postsurgical gastroparesis syndrome and its diagnosis and treatment. Chin J Dig Dis 7:76–82 PubMedCrossRef
17.
Duffas JP, Suc B, Msika S et al (2005) A controlled randomized multicenter trial of pancreatogastrostomy or pancreatojejunostomy after pancreatoduodenectomy. Am J Surg 189:720–729 PubMedCrossRef
18.
19.
Ernest van Heurn LW, Saing H, Tam PK (2003) Cholangitis after hepatic portoenterostomy for biliary atresia: a multivariate analysis of risk factors. J Pediatr 142:566–571 PubMedCrossRef
20.
Farley DR, Schwall G, Trede M (1996) Completion pancreatectomy for surgical complications after pancreaticoduodenectomy. Br J Surg 83:176–179 PubMedCrossRef
21.
22.
Gerritsen A, Besselink MG, Gouma DJ et al (2013) Systematic review of five feeding routes after pancreatoduodenectomy. Br J Surg 100:589–598 PubMedCrossRef
23.
Harnoss JC, Ulrich AB, Harnoss JM et al (2014) Use and results of consensus definitions in pancreatic surgery: a systematic review. Surgery 155:47–57 PubMedCrossRef
24.
Hawkyard CV, Koerner RJ (2007) The use of erythromycin as a gastrointestinal prokinetic agent in adult critical care: benefits versus risks. J Antimicrob Chemother 59:347–358 PubMedCrossRef
25.
Itoh Z, Nakaya M, Suzuki T et al (1984) Erythromycin mimics exogenous motilin in gastrointestinal contractile activity in the dog. Am J Physiol 247:G688–G694
26.
Jakab F, Regoly-Merey J, Zavodszky Z et al (1988) Postoperative pancreatitis after biliary and gastric operations. Acta Chir Hung 29:241–249 PubMed
27.
Kennedy EP, Rosato EL, Sauter PK et al (2007) Initiation of a critical pathway for pancreaticoduodenectomy at an academic institution – the first step in multidisciplinary team building. J Am Coll Surg 204:917–923 PubMedCrossRef
28.
Kollmar O, Moussavian MR, Richter S et al (2008) Prophylactic octreotide and delayed gastric emptying after pancreaticoduodenectomy: results of a prospective randomized double-blinded placebo-controlled trial. Eur J Surg Oncol 34:868–875 PubMedCrossRef
29.
Kunstman JW, Klemen ND, Fonseca AL et al (2013) Nasogastric drainage may be unnecessary after pancreaticoduodenectomy: a comparison of routine vs selective decompression. J Am Coll Surg 217:481–488 PubMedCrossRef
30.
Lamian V, Rich A, Ma Z et al (2006) Characterization of agonist-induced motilin receptor trafficking and its implications for tachyphylaxis. Mol Pharmacol 69:109–118 PubMed
31.
Lankisch PG, Apte M, Banks PA (2015) Acute pancreatitis. Lancet 6736:60649–60648
32.
Lee JG (2009) Diagnosis and management of acute cholangitis. Nat Rev Gastroenterol Hepatol 6:533–541 PubMedCrossRef
33.
Lermite E, Sommacale D, Piardi T et al (2013) Complications after pancreatic resection: diagnosis, prevention and management. Clin Res Hepatol Gastroenterol 37:230–239 PubMedCrossRef
34.
Luttikhold J, de Ruijter FM, van Norren K et al (2013) Review article: the role of gastrointestinal hormones in the treatment of delayed gastric emptying in critically ill patients. Aliment Pharmacol Ther 38:573–583 PubMedCrossRef
35.
Lytras D, Paraskevas KI, Avgerinos C et al (2007) Therapeutic strategies for the management of delayed gastric emptying after pancreatic resection. Langenbecks Arch Surg 392:1–12 PubMedCrossRef
36.
Martignoni ME, Friess H, Sell F et al (2000) Enteral nutrition prolongs delayed gastric emptying in patients after Whipple resection. Am J Surg 180:18–23 PubMedCrossRef
37.
Miyagawa S, Makuuchi M, Kawasaki S et al (1994) Changes in serum amylase level following hepatic resection in chronic liver disease. Arch Surg 129:634–638 PubMedCrossRef
38.
Musgrove JE, Grindlay JH, Karlson AG (1952) Intestinal biliary reflex after anastomosis of common duct to duodenum or jejunum; an experimental study. AMA Arch Surg 64:579–589 PubMedCrossRef
39.
Nguyen NQ, Chapman M, Fraser RJ et al (2007) Prokinetic therapy for feed intolerance in critical illness: one drug or two? Crit Care Med 35:2561–2567 PubMedCrossRef
40.
Nussbaum DP, Penne K, Stinnett SS et al (2015) A standardized care plan is associated with shorter hospital length of stay in patients undergoing pancreaticoduodenectomy. J Surg Res 193:237–245 PubMedCrossRef
41.
Ohwada S, Satoh Y, Kawate S et al (2001) Low-dose erythromycin reduces delayed gastric emptying and improves gastric motility after Billroth I pylorus-preserving pancreaticoduodenectomy. Ann Surg 234:668–674 PubMedCrossRefPubMedCentral
42.
Okano K, Asano E, Oshima M et al (2013) Omental flap wrapping with fixation to the cut surface of the liver for reducing delayed gastric emptying after left-sided hepatectomy. Surg Today 43:1425–1432 PubMedCrossRef
43.
Okudaira T, Kotegawa T, Imai H et al (2007) Effect of the treatment period with erythromycin on cytochrome P450 3A activity in humans. J Clin Pharmacol 47:871–876 PubMedCrossRef
44.
Popping DM, Elia N, Van Aken HK et al (2014) Impact of epidural analgesia on mortality and morbidity after surgery: systematic review and meta-analysis of randomized controlled trials. Ann Surg 259:1056–1067 PubMedCrossRef
45.
Porter GA, Pisters PW, Mansyur C et al (2000) Cost and utilization impact of a clinical pathway for patients undergoing pancreaticoduodenectomy. Ann Surg Oncol 7:484–489 PubMedCrossRef
46.
Pratt WB, Steinbrook RA, Maithel SK et al (2008) Epidural analgesia for pancreatoduodenectomy: a critical appraisal. J Gastrointest Surg 12:1207–1220 PubMedCrossRef
47.
Raty S, Sand J, Lantto E et al (2006) Postoperative acute pancreatitis as a major determinant of postoperative delayed gastric emptying after pancreaticoduodenectomy. J Gastrointest Surg 10:1131–1139 PubMedCrossRef
48.
Raty S, Sand J, Nordback I (2007) Detection of postoperative pancreatitis after pancreatic surgery by urine trypsinogen strip test. Br J Surg 94:64–69 PubMedCrossRef
49.
Robertson N, Gallacher PJ, Peel N et al (2012) Implementation of an enhanced recovery programme following pancreaticoduodenectomy. Hpb 14:700–708 PubMedCrossRefPubMedCentral
50.
Roland CL, Mansour JC, Schwarz RE (2012) Routine nasogastric decompression is unnecessary after pancreatic resections. Arch Surg 147:287–289 PubMedCrossRef
51.
van Santvoort HC, Besselink MG, Bakker OJ et al (2010) A step-up approach or open necrosectomy for necrotizing pancreatitis. N Engl J Med 362:1491–1502 PubMedCrossRef
52.
Sathasivam S, Ritchie A, Brooks AJ et al (2004) Acute pancreatitis following liver resection: report of three fatal cases and a review of the literature. ANZ J Surg 74:643–645 PubMedCrossRef
53.
Schmitz V, Neumann UP, Puhl G et al (2006) Surgical complications and long-term outcome of different biliary reconstructions in liver transplantation for primary sclerosing cholangitis-choledochoduodenostomy versus choledochojejunostomy. Am J Transplant 6:379–385 PubMedCrossRef
54.
Shaffer D, Singer S, Korvick J et al (2002) Concomitant risk factors in reports of torsades de pointes associated with macrolide use: review of the United States Food and Drug Administration Adverse Event Reporting System. Clin Infect Dis 35:197–200 PubMedCrossRef
55.
Shao Z, Jin G, Ji W et al (2015) The role of fast-track surgery in pancreaticoduodenectomy: a single-center review of 635 consecutive resections. Int J Surg 9191:00025–00024
56.
Sulberg D, Chromik AM, Koster O et al (2010) [Prevention and management of postoperative complications in pancreatic surgery]. Zentralbl Chir 135:129–138 PubMedCrossRef
57.
Tanaka A, Takada T, Kawarada Y et al (2007) Antimicrobial therapy for acute cholangitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg 14:59–67 PubMedCrossRefPubMedCentral
58.
Traut U, Brugger L, Kunz R et al (2008) Systemic prokinetic pharmacologic treatment for postoperative adynamic ileus following abdominal surgery in adults. Cochrane Database Syst Rev 1:CD004930 PubMed
59.
Uemura K, Murakami Y, Hayashidani Y et al (2008) Randomized clinical trial to assess the efficacy of ulinastatin for postoperative pancreatitis following pancreaticoduodenectomy. J Surg Oncol 98:309–313 PubMedCrossRef
60.
Vather R, Bissett I (2013) Management of prolonged post-operative ileus: evidence-based recommendations. ANZ J Surg 83:319–324 PubMedCrossRef
61.
Vather R, O’Grady G, Bissett IP et al (2014) Postoperative ileus: mechanisms and future directions for research. Clin Exp Pharmacol Physiol 41:358–370 PubMedCrossRef
62.
Vather R, Trivedi S, Bissett I (2013) Defining postoperative ileus: results of a systematic review and global survey. J Gastrointest Surg 17:962–972 PubMedCrossRef
63.
Warschkow R, Ukegjini K, Tarantino I et al (2012) Diagnostic study and meta-analysis of C-reactive protein as a predictor of postoperative inflammatory complications after pancreatic surgery. J Hepatobiliary Pancreat Sci 19:492–500 PubMedCrossRef
64.
Wehner S, Vilz TO, Stoffels B et al. (2012) Immune mediators of postoperative ileus. Langenbecks Arch Surg 397:591–601 PubMedCrossRef
65.
Welsch T, Borm M, Degrate L et al (2010) Evaluation of the International Study Group of Pancreatic Surgery definition of delayed gastric emptying after pancreatoduodenectomy in a high-volume centre. Br J Surg 97:1043–1050 PubMedCrossRef
66.
Wente MN, Bassi C, Dervenis C et al (2007) Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS). Surgery 142:761–768 PubMedCrossRef
67.
68.
Winter JM, Cameron JL, Campbell KA et al (2006) 1423 pancreaticoduodenectomies for pancreatic cancer: a single-institution experience. J Gastrointest Surg 10:1199–1210 PubMedCrossRef
69.
Yeo CJ, Barry MK, Sauter PK et al (1993) Erythromycin accelerates gastric emptying after pancreaticoduodenectomy. A prospective, randomized, placebo-controlled trial. Ann Surg 218:229–237 PubMedCrossRefPubMedCentral
Metadaten
Titel
Behandlung postoperativer Passagestörungen, Cholangitis und Pankreatitis
verfasst von
Dr. Dr. Tobias Schulze
Claus-Dieter Heidecke
Publikationsdatum
01.09.2015
Verlag
Springer Vienna
Erschienen in
Wiener klinisches Magazin / Ausgabe 4/2015
Print ISSN: 1869-1757
Elektronische ISSN: 1613-7817
DOI
https://doi.org/10.1007/s00740-015-0063-4

Weitere Artikel der Ausgabe 4/2015

Wiener klinisches Magazin 4/2015 Zur Ausgabe

Pulmologie

Medikamentös induzierte Lungenerkrankungen

Pathologie

Molekulare Pathologie des kolorektalen Karzinoms

aktuell

Neue Konzepte und Pilotprojekte

Editorial

Im Dilemma zwischen Freiheit und Verbot

Anästhesie

Anästhesie in der Thoraxchirurgie

Panorama

Panorama