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Erschienen in: Wiener klinisches Magazin 6/2015

01.12.2015 | Hämatologie

Autologe Stammzelltransplantation bei Myelompatienten

Ansätze zur Verbesserung der Ergebnisse

verfasst von: OA Priv.-Doz. Dr. Niklas Zojer

Erschienen in: Wiener klinisches Magazin | Ausgabe 6/2015

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Zusammenfassung

Mit moderner Induktionstherapie gefolgt von Hochdosistherapie und autologer Transplantation werden heute 5-Jahres-Überlebensraten von 50–60 % erreicht. Die Transplantation im Rahmen der Erstlinientherapie dürfte sich als Standard weiterhin behaupten. Eine Doppeltransplantation kann in Einzelfällen sinnvoll sein, etwa bei Patienten, die während der Induktion nicht zumindest eine VGPR erreichen oder bei Patienten mit 17p-Deletion. Mit Konsolidierungs- bzw. Erhaltungsstrategien lässt sich die Remission vertiefen bzw. die Zeit bis zur Progression verlängern.
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Metadaten
Titel
Autologe Stammzelltransplantation bei Myelompatienten
Ansätze zur Verbesserung der Ergebnisse
verfasst von
OA Priv.-Doz. Dr. Niklas Zojer
Publikationsdatum
01.12.2015
Verlag
Springer Vienna
Erschienen in
Wiener klinisches Magazin / Ausgabe 6/2015
Print ISSN: 1869-1757
Elektronische ISSN: 1613-7817
DOI
https://doi.org/10.1007/s00740-015-0077-y