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Erschienen in: Wiener klinische Wochenschrift 13-14/2012

01.07.2012 | case report

Attempted suicide under high dose dopaminergic therapy including apomorphine

verfasst von: Walter Struhal, MD, Michael Guger, MD, Stephanie Hödl, MD, Sok-Chu Ung, MD, Prof Michael Bach, MD, Prof. Gerhard Ransmayr, MD

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 13-14/2012

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Summary

Impulse control disorder during continuous subcutaneous apomorphine treatment (CAI) was recently reported. We describe a 54-year-old patient with familial Parkinson’s disease, who after initiation of CAI in addition to high dose levodopa and amantadine, developed impulse control disorder (major financial loss related to risky transactions and self-medication), psychosis and depression, which lead up to attempted suicide. To our knowledge, this is the first case of attempted suicide under apomorphine treatment.
Literatur
1.
Zurück zum Zitat Voon V, Hassan K, Zurowski M, Duff-Canning S, de Souza M, Fox S, et al. Prospective prevalence of pathologic gambling and medication association in Parkinson disease. Neurology. 2006;66:1750–2.PubMedCrossRef Voon V, Hassan K, Zurowski M, Duff-Canning S, de Souza M, Fox S, et al. Prospective prevalence of pathologic gambling and medication association in Parkinson disease. Neurology. 2006;66:1750–2.PubMedCrossRef
2.
Zurück zum Zitat Soulas T, Gurruchaga JM, Palfi S, Cesaro P, Nguyen JP, Fenelon G. Attempted and completed suicides after subthalamic nucleus stimulation for Parkinson’s disease. J Neurol Neurosurg Psychiatry. 2008;79:952–4.PubMedCrossRef Soulas T, Gurruchaga JM, Palfi S, Cesaro P, Nguyen JP, Fenelon G. Attempted and completed suicides after subthalamic nucleus stimulation for Parkinson’s disease. J Neurol Neurosurg Psychiatry. 2008;79:952–4.PubMedCrossRef
3.
Zurück zum Zitat Bxarone P, Poewe W, Albrecht S, Debieuvre C, Massey D, Rascol O, et al. Pramipexole for the treatment of depressive symptoms in patients with Parkinson’s disease: a randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2010;9:573–80.CrossRef Bxarone P, Poewe W, Albrecht S, Debieuvre C, Massey D, Rascol O, et al. Pramipexole for the treatment of depressive symptoms in patients with Parkinson’s disease: a randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2010;9:573–80.CrossRef
4.
Zurück zum Zitat Parkinson Study Group. Pramipexole vs Levodopa as Initial Treatment for Parkinson Disease: a randomized controlled trial. JAMA. 2000;284:1931–8.CrossRef Parkinson Study Group. Pramipexole vs Levodopa as Initial Treatment for Parkinson Disease: a randomized controlled trial. JAMA. 2000;284:1931–8.CrossRef
5.
Zurück zum Zitat Nock MK, Borges G, Bromet EJ, Alonso J, Angermeyer M, Beautrais A, et al. Cross-national prevalence and risk factors for suicidal ideation, plans and attempts. Br J Psychiatry.2008;192:98–105.PubMedCrossRef Nock MK, Borges G, Bromet EJ, Alonso J, Angermeyer M, Beautrais A, et al. Cross-national prevalence and risk factors for suicidal ideation, plans and attempts. Br J Psychiatry.2008;192:98–105.PubMedCrossRef
6.
Zurück zum Zitat Joutsa J, Martikainen K, Vahlberg T, Voon V, Kaasinen V. Impulse control disorders and depression in finnish patients with Parkinson’s disease. Parkinsonism.Relat Disord. 2011;18(2):155–60.PubMedCrossRef Joutsa J, Martikainen K, Vahlberg T, Voon V, Kaasinen V. Impulse control disorders and depression in finnish patients with Parkinson’s disease. Parkinsonism.Relat Disord. 2011;18(2):155–60.PubMedCrossRef
7.
Zurück zum Zitat Stamey W, Jankovic J. Impulse control disorders and pathological gambling in patients with Parkinson disease. Neurologist. 2008;14:89–99.PubMedCrossRef Stamey W, Jankovic J. Impulse control disorders and pathological gambling in patients with Parkinson disease. Neurologist. 2008;14:89–99.PubMedCrossRef
8.
Zurück zum Zitat Antonini A. Continuous dopaminergic stimulation–from theory to clinical practice. Parkinsonism.Relat Disord. 2007;(13 Suppl):S24–8.CrossRef Antonini A. Continuous dopaminergic stimulation–from theory to clinical practice. Parkinsonism.Relat Disord. 2007;(13 Suppl):S24–8.CrossRef
9.
Zurück zum Zitat Poewe W. When a Parkinson’s disease patient starts to hallucinate. Pract Neurol. 2008;8:238–41.PubMedCrossRef Poewe W. When a Parkinson’s disease patient starts to hallucinate. Pract Neurol. 2008;8:238–41.PubMedCrossRef
Metadaten
Titel
Attempted suicide under high dose dopaminergic therapy including apomorphine
verfasst von
Walter Struhal, MD
Michael Guger, MD
Stephanie Hödl, MD
Sok-Chu Ung, MD
Prof Michael Bach, MD
Prof. Gerhard Ransmayr, MD
Publikationsdatum
01.07.2012
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 13-14/2012
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-012-0202-5

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