Association between high cytomegalovirus antibody titers and blood pressure in the adult Kazakh and Han Chinese populations
- 03.08.2017
- original article
Erschienen in:
- Verfasst von
- Na Tang
- Jia-Wei Li
- Yong-Min Liu
- Hua Zhong
- La-Mei Wang
- Feng-Mei Deng
- Jing Hui
- Yuan-Yuan Qu
- Fang He
- Erschienen in
- Wiener klinische Wochenschrift | Ausgabe 19-20/2017
Summary
Background
Human cytomegalovirus (CMV) has been linked to the pathogenesis of elevated arterial blood pressure (BP). Our study aimed to determine the association between anti-CMV titers and arterial BP in the Kazakh and Han Chinese populations.
Material and methods
Kazakh and Han (n = 800 each) (age, ≥18 years) subjects from Xinjiang, China were examined for anti-CMV immunoglobulin (Ig)G titers using a commercially available enzyme-linked immunosorbent assay (ELISA) kit. The highest anti-CMV titer tertiles determined within gender and ethnicity groups were compared against the two lower tertiles and seronegative samples.
Results
Multivariate linear regression analysis revealed that anti-CMV titers were independent determinants for elevated systolic (p = 0.006) BP in Kazakh women and inversely associated with systolic (p = 0.004) and mean arterial (p = 0.019) BP in Han women.
Conclusion
The association between CMV infection and/or resulting immune response and BP elevation differed by sex and ethnicity. In Kazakh women, they were associated with elevated BP and the opposite was true among Han women.
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- Titel
- Association between high cytomegalovirus antibody titers and blood pressure in the adult Kazakh and Han Chinese populations
- Verfasst von
-
Na Tang
Jia-Wei Li
Yong-Min Liu
Hua Zhong
La-Mei Wang
Feng-Mei Deng
Jing Hui
Yuan-Yuan Qu
Fang He
- Publikationsdatum
- 03.08.2017
- Verlag
- Springer Vienna
- Erschienen in
-
Wiener klinische Wochenschrift / Ausgabe 19-20/2017
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671 - DOI
- https://doi.org/10.1007/s00508-017-1239-2
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