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Erschienen in: Wiener klinische Wochenschrift 3-4/2016

01.02.2016 | original article

Assessment of smoking for low bone mineral density in postmenopausal Turkish women

verfasst von: Ugur Ugurlu, MD, Asst. Prof. Dr. Umit Nayki, Asst. Prof. Dr. Cenk Nayki, Asst. Prof. Dr. Pasa Ulug, Mehmet Kulhan, MD, Prof. Dr. Yusuf Yildirim

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 3-4/2016

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Summary

Objective

To investigate the effect of cigarette smoking on bone mineral density (BMD) in postmenopausal Turkish women.

Study design

A total of 175 postmenopausal Turkish women admitted to Tepecik Training and Research Hospital for a routine menopausal checkup were included in this study. All participants completed a questionnaire regarding their age, educational status, parity, number of abortus, time since menopause, caffeine intake, tobacco use, alcohol consumption, history of a previous fracture related to trauma, and taking any medication for menopause and osteoporosis. Of all subjects, 23.3 % (n = 39) were smokers and 77.7 % (n = 136) were nonsmokers. T-scores and Z-scores of vertebra and femur neck were assessed using dual energy X-ray absorptiometry (DXA). For analyzing the results, Student t-test, one-way ANOVA, Mann–Whitney U test, Pearson correlation, and Kruskal–Wallis test were performed.

Results

Femur T-scores (− 0.78 ± 1.07 vs. − 0.32 ± 1.56) and vertebra T-scores (− 2.26 ± 1.23 vs. − 1.82 ± 1.04) were significantly lower in smoking women than nonsmoking women (p < 0.05). However, there were no significant difference between duration of smoking, number of cigarettes consumed per day, and BMD (p > 0.05)

Conclusion

Cigarette smoking is one of the modifiable risk factors influencing bone density in postmenopausal Turkish women. “Cessation of cigarette” should be recommended for lifestyle modifications to prevent postmenopausal osteoporosis.
Literatur
1.
Zurück zum Zitat Brook JS, Balka EB, Zhang C. The smoking patterns of women in their forties: their relationship to later osteoporosis. Psychol Rep. 2012;110(2):351–62.PubMedCentralCrossRefPubMed Brook JS, Balka EB, Zhang C. The smoking patterns of women in their forties: their relationship to later osteoporosis. Psychol Rep. 2012;110(2):351–62.PubMedCentralCrossRefPubMed
2.
Zurück zum Zitat Riggs BL, Melton LJ III. The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone. 1995;17(5):505–11.CrossRef Riggs BL, Melton LJ III. The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone. 1995;17(5):505–11.CrossRef
3.
Zurück zum Zitat Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Toseson A. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025. J Bone Miner Res. 2007;22(3):465–75.CrossRefPubMed Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Toseson A. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025. J Bone Miner Res. 2007;22(3):465–75.CrossRefPubMed
4.
Zurück zum Zitat Koeck CM, Schwappach DL, Niemann FM, Strassman TJ, Ebner H, Klaushofer K. Incidence and costs of osteoporosis-associated hip fractures in Austria. Wien Klin Wochenschr. 2001;113:371–7.PubMed Koeck CM, Schwappach DL, Niemann FM, Strassman TJ, Ebner H, Klaushofer K. Incidence and costs of osteoporosis-associated hip fractures in Austria. Wien Klin Wochenschr. 2001;113:371–7.PubMed
5.
Zurück zum Zitat Preisinger E, Leitner G, Uher E, Alacamlioglu Y, Seidi G, Marktl W, et al. Nutrition and osteoporosis: a nutritional analysis of women in postmenopause. Wien Klin Wochenschr. 1995;197:418–22. Preisinger E, Leitner G, Uher E, Alacamlioglu Y, Seidi G, Marktl W, et al. Nutrition and osteoporosis: a nutritional analysis of women in postmenopause. Wien Klin Wochenschr. 1995;197:418–22.
6.
Zurück zum Zitat Nasto LA, Fusco A, Colangelo D, et al. Clinical predictors of vertebral osteoporotic fractures in post-menopausal women: a cross-sectional analysis. Eur Rev Med Pharmacol Sci. 2012;16(9):1227–34.PubMed Nasto LA, Fusco A, Colangelo D, et al. Clinical predictors of vertebral osteoporotic fractures in post-menopausal women: a cross-sectional analysis. Eur Rev Med Pharmacol Sci. 2012;16(9):1227–34.PubMed
7.
Zurück zum Zitat Benson BW, Shulman JD. Inclusion of tobacco exposure as a predictive factor for decreased bone mineral content. Nicotine Tob Res. 2005;7(5):719–24.CrossRefPubMed Benson BW, Shulman JD. Inclusion of tobacco exposure as a predictive factor for decreased bone mineral content. Nicotine Tob Res. 2005;7(5):719–24.CrossRefPubMed
8.
Zurück zum Zitat Law MR, Hackshaw AK. A meta-analysis of cigarette smoking, bone mineral density and risk of hip fracture: recognition of a major effect. BMJ. 1997;315(7112):841–6.PubMedCentralCrossRefPubMed Law MR, Hackshaw AK. A meta-analysis of cigarette smoking, bone mineral density and risk of hip fracture: recognition of a major effect. BMJ. 1997;315(7112):841–6.PubMedCentralCrossRefPubMed
9.
Zurück zum Zitat Hongo M, Itoi E, Sinaki M, et al. Effect of low-intensity back exercise on quality of life and back extensor strength in patients with osteoporosis: a randomized controlled trial. Osteoporos Int. 2007;18(10):1389–95.CrossRefPubMed Hongo M, Itoi E, Sinaki M, et al. Effect of low-intensity back exercise on quality of life and back extensor strength in patients with osteoporosis: a randomized controlled trial. Osteoporos Int. 2007;18(10):1389–95.CrossRefPubMed
10.
Zurück zum Zitat Kanesaki K. Vertebral deformities in female patients with osteoporosis: influence of trauma and bone mineral density. Kurume Med J. 2004;51(3–4):203–13.CrossRefPubMed Kanesaki K. Vertebral deformities in female patients with osteoporosis: influence of trauma and bone mineral density. Kurume Med J. 2004;51(3–4):203–13.CrossRefPubMed
11.
Zurück zum Zitat Gardner MJ, Brophy RH, Demetrakopoulos D, et al. Interventions to improve osteoporosis treatment following hip fracture. A prospective, randomized trial. J Bone Joint Surg Am. 2005;87(1):3–7.CrossRefPubMed Gardner MJ, Brophy RH, Demetrakopoulos D, et al. Interventions to improve osteoporosis treatment following hip fracture. A prospective, randomized trial. J Bone Joint Surg Am. 2005;87(1):3–7.CrossRefPubMed
12.
Zurück zum Zitat Health Quality Ontario. Utilization of DXA bone mineral densitometry in Ontario. Ont Health Technol Assess Ser. 2006;6:1–180. Health Quality Ontario. Utilization of DXA bone mineral densitometry in Ontario. Ont Health Technol Assess Ser. 2006;6:1–180.
13.
Zurück zum Zitat Genant HK, Cooper C, Poor G, Reid I, Ehrlich G, Kanis J, et al. Interim report and recommendations of the World Health Organization Task-Force for Osteoporosis. Osteoporos Int. 1999;10:259–64.CrossRefPubMed Genant HK, Cooper C, Poor G, Reid I, Ehrlich G, Kanis J, et al. Interim report and recommendations of the World Health Organization Task-Force for Osteoporosis. Osteoporos Int. 1999;10:259–64.CrossRefPubMed
14.
Zurück zum Zitat Lewiecki EM, Watts NB, McClung MR, Petak SM, Bachrach LK, Shepherd JA, et al. Official positions of the international society for clinical densitometry. J Clin Endocrinol Metab. 2004;89:3651–5.CrossRefPubMed Lewiecki EM, Watts NB, McClung MR, Petak SM, Bachrach LK, Shepherd JA, et al. Official positions of the international society for clinical densitometry. J Clin Endocrinol Metab. 2004;89:3651–5.CrossRefPubMed
15.
Zurück zum Zitat Nguyen TV, Center JR, Eisman JA. Osteoporosis: underrated, underdiagnosed, and undertreated. Med J Aus. 2004;180(5):18–22. Nguyen TV, Center JR, Eisman JA. Osteoporosis: underrated, underdiagnosed, and undertreated. Med J Aus. 2004;180(5):18–22.
16.
Zurück zum Zitat Cooper C, Wickham C. Cigarette smoking and the risk of age-related fracturs. In: Wald N, Baron J, editors Smoking and hormone-related disorders. Oxford: Oxford University Press; 1990. pp. 93–100. Cooper C, Wickham C. Cigarette smoking and the risk of age-related fracturs. In: Wald N, Baron J, editors Smoking and hormone-related disorders. Oxford: Oxford University Press; 1990. pp. 93–100.
17.
Zurück zum Zitat Baheraei A, Pocock NA, Eisman JA, Nguyen ND, Nguyen TV. Bone mineral density, body mass index and cigarette smoking among Iranian women: implications for prevention. BMC Musculooskelet Disord. 2005;6:34.CrossRef Baheraei A, Pocock NA, Eisman JA, Nguyen ND, Nguyen TV. Bone mineral density, body mass index and cigarette smoking among Iranian women: implications for prevention. BMC Musculooskelet Disord. 2005;6:34.CrossRef
18.
Zurück zum Zitat Ward KD, Klesges RC. A meta-analysis of the effects of cigarette smoking on bone mineral density. Calcif Tissue Int. 2001;68(5):259–70.CrossRefPubMed Ward KD, Klesges RC. A meta-analysis of the effects of cigarette smoking on bone mineral density. Calcif Tissue Int. 2001;68(5):259–70.CrossRefPubMed
19.
Zurück zum Zitat Akhter MP, Iwaniec UT, Haynatzki GR, Fung YK, Cullen DM, Recker RR. Effects of nicotine on bone mass and strength in aged female rats. J Orthop Res. 2003;21(1):14–9.CrossRefPubMed Akhter MP, Iwaniec UT, Haynatzki GR, Fung YK, Cullen DM, Recker RR. Effects of nicotine on bone mass and strength in aged female rats. J Orthop Res. 2003;21(1):14–9.CrossRefPubMed
20.
Zurück zum Zitat Blum M, Harris SS, Must A, Phillips SM, Rand WM, Dawson-Hughes B. Household tobacco smoke exposure is negatively associated with premenopausal bone mass. Osteoporos Int. 2002;13(8):663–8.CrossRefPubMed Blum M, Harris SS, Must A, Phillips SM, Rand WM, Dawson-Hughes B. Household tobacco smoke exposure is negatively associated with premenopausal bone mass. Osteoporos Int. 2002;13(8):663–8.CrossRefPubMed
21.
Zurück zum Zitat Daniel M, Martin AD, Drinkwater DT. Cigarette smoking, steroid hormones, and bone mineral density in young women. Calcif Tissue Int. 1992;50(4):300–5.CrossRefPubMed Daniel M, Martin AD, Drinkwater DT. Cigarette smoking, steroid hormones, and bone mineral density in young women. Calcif Tissue Int. 1992;50(4):300–5.CrossRefPubMed
22.
Zurück zum Zitat Johnell O, Nilsson BE. Life-style and bone mineral mass in perimenopausal women. Calcif Tissue Int. 1984;36(4):354–6.CrossRefPubMed Johnell O, Nilsson BE. Life-style and bone mineral mass in perimenopausal women. Calcif Tissue Int. 1984;36(4):354–6.CrossRefPubMed
23.
Zurück zum Zitat Flicker L, Hopper JL, Rodgers L, Kaymakcı B, Green RM, Wark JD. Bone density determinants in elderly women: a twin study. J Bone Miner Res. 1995;10(11):1607–13.CrossRefPubMed Flicker L, Hopper JL, Rodgers L, Kaymakcı B, Green RM, Wark JD. Bone density determinants in elderly women: a twin study. J Bone Miner Res. 1995;10(11):1607–13.CrossRefPubMed
24.
Zurück zum Zitat Riebel GD, Boden SD, Whitesides TE, Hutton WC. The effect of nicotine on incorporation of cancellous bone graft in an animal model. Spine. 1995;20(20):2198–202.CrossRefPubMed Riebel GD, Boden SD, Whitesides TE, Hutton WC. The effect of nicotine on incorporation of cancellous bone graft in an animal model. Spine. 1995;20(20):2198–202.CrossRefPubMed
25.
Zurück zum Zitat Broulik PD, Jarab J. The effect of chronic nicotine administration on bone mineral content in mice. Horm Metab Res. 1993;25(4):219–21.CrossRefPubMed Broulik PD, Jarab J. The effect of chronic nicotine administration on bone mineral content in mice. Horm Metab Res. 1993;25(4):219–21.CrossRefPubMed
26.
Zurück zum Zitat Krall EA, Dawson-Hughes B. Smoking and bone loss among postmenopausal women. J Bone Miner Res. 1991;6(4):331–8.CrossRefPubMed Krall EA, Dawson-Hughes B. Smoking and bone loss among postmenopausal women. J Bone Miner Res. 1991;6(4):331–8.CrossRefPubMed
27.
Zurück zum Zitat Landin-Wilhelmsen K, Wilhelmsen K, Lappas G, et al. Serum intact parathyroid hormone in a random population sample of men and women: relationship to anthropometry, life-style factors, blood pressure, and vitamin D. Calcif Tissue Int. 1995;56:104–8.CrossRefPubMed Landin-Wilhelmsen K, Wilhelmsen K, Lappas G, et al. Serum intact parathyroid hormone in a random population sample of men and women: relationship to anthropometry, life-style factors, blood pressure, and vitamin D. Calcif Tissue Int. 1995;56:104–8.CrossRefPubMed
28.
Zurück zum Zitat Gordon T. Factors associated with serum alkaline phosphatase level. Arch Pathol Lab Med. 1993;117(2):187–90.PubMed Gordon T. Factors associated with serum alkaline phosphatase level. Arch Pathol Lab Med. 1993;117(2):187–90.PubMed
29.
Zurück zum Zitat Hirota Y, Hirota T, Fukuda K, et al. Association of alcohol intake, cigarette smoking and occupational status with the risk of idiopathic osteonecrosis of the femoral head. Am J Epidemiol. 1993;137(5):530–8.PubMed Hirota Y, Hirota T, Fukuda K, et al. Association of alcohol intake, cigarette smoking and occupational status with the risk of idiopathic osteonecrosis of the femoral head. Am J Epidemiol. 1993;137(5):530–8.PubMed
30.
Zurück zum Zitat Matsuo K, Hirohata T, Sugioka Y, Ikeda M, Fukuda A. Influence of alcohol intake, cigarette smoking, and occupational status on idiopathic osteonecrosis of the femoral head. Clin Orthop Relat Res. 1988;234:115–23.PubMed Matsuo K, Hirohata T, Sugioka Y, Ikeda M, Fukuda A. Influence of alcohol intake, cigarette smoking, and occupational status on idiopathic osteonecrosis of the femoral head. Clin Orthop Relat Res. 1988;234:115–23.PubMed
31.
Zurück zum Zitat Klesges RC, Meyers AW, Klesges LM, La Vasque M. Smoking, body weight and their effects on smoking behaviour: a comprehensive review of the literature. Phychol Bull. 1989;106(2):204–30.CrossRef Klesges RC, Meyers AW, Klesges LM, La Vasque M. Smoking, body weight and their effects on smoking behaviour: a comprehensive review of the literature. Phychol Bull. 1989;106(2):204–30.CrossRef
32.
Zurück zum Zitat Rubin CT, Lanyon LE. Regulation of bone mass by mechanical strain magnitude. Calcif Tissue Int. 1985;37(4):411–7.CrossRefPubMed Rubin CT, Lanyon LE. Regulation of bone mass by mechanical strain magnitude. Calcif Tissue Int. 1985;37(4):411–7.CrossRefPubMed
33.
Zurück zum Zitat Demirbag D, Ozdemir F, Ture M. Effects of coffee consumption and smoking habit on bone mineral density. Rheumotol Int. 2006;26(6):530–5.CrossRef Demirbag D, Ozdemir F, Ture M. Effects of coffee consumption and smoking habit on bone mineral density. Rheumotol Int. 2006;26(6):530–5.CrossRef
34.
Zurück zum Zitat Svejme O, Ahlborg HG, Nilsson JA, Karlsson MK. Low BMD is an independent predictor of fracture and early menopause of mortality in post-menopausal women—a 34-year prospective study. Maturitas. 2013;74(4):341–5.CrossRefPubMed Svejme O, Ahlborg HG, Nilsson JA, Karlsson MK. Low BMD is an independent predictor of fracture and early menopause of mortality in post-menopausal women—a 34-year prospective study. Maturitas. 2013;74(4):341–5.CrossRefPubMed
35.
Zurück zum Zitat Khan A, Fortier M; Menopause and Osteoporosis Working Group, Fortier M, Reid R, Abramson BL, et al. Osteoporosis in menopause. J Obstet Gynaecol Can. 2014;36(9):839–40. Khan A, Fortier M; Menopause and Osteoporosis Working Group, Fortier M, Reid R, Abramson BL, et al. Osteoporosis in menopause. J Obstet Gynaecol Can. 2014;36(9):839–40.
36.
Zurück zum Zitat Khoo CC, Woo J, Leung PC, Kwok A, Kwok T. Determinants of bone mineral density in older postmenopausal Chinese women. Climacteric. 2011;14(3):378–83.CrossRefPubMed Khoo CC, Woo J, Leung PC, Kwok A, Kwok T. Determinants of bone mineral density in older postmenopausal Chinese women. Climacteric. 2011;14(3):378–83.CrossRefPubMed
37.
Zurück zum Zitat Nahas EA, Kawakami MS, Nahas-Netto J, Butros Dde A, Cangussu LM, Rodrigues AB. Assessment of risk factors for low bone mineral density in Brazilian postmenopausal women. Climacteric. 2011;14(2):220–7.CrossRefPubMed Nahas EA, Kawakami MS, Nahas-Netto J, Butros Dde A, Cangussu LM, Rodrigues AB. Assessment of risk factors for low bone mineral density in Brazilian postmenopausal women. Climacteric. 2011;14(2):220–7.CrossRefPubMed
38.
Zurück zum Zitat Jones G, Scott FS. A cross-sectional study of smoking on bone mineral density in premenopausal parous women: effect of body mass index, breastfeeding, and sports participation. J Bone Miner Res. 1999;14(9):1628–33.CrossRefPubMed Jones G, Scott FS. A cross-sectional study of smoking on bone mineral density in premenopausal parous women: effect of body mass index, breastfeeding, and sports participation. J Bone Miner Res. 1999;14(9):1628–33.CrossRefPubMed
Metadaten
Titel
Assessment of smoking for low bone mineral density in postmenopausal Turkish women
verfasst von
Ugur Ugurlu, MD
Asst. Prof. Dr. Umit Nayki
Asst. Prof. Dr. Cenk Nayki
Asst. Prof. Dr. Pasa Ulug
Mehmet Kulhan, MD
Prof. Dr. Yusuf Yildirim
Publikationsdatum
01.02.2016
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 3-4/2016
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-015-0867-7

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