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Erschienen in: Journal für Klinische Endokrinologie und Stoffwechsel 4/2021

04.11.2021 | Originalien

Aktuelle Therapiestrategien beim papillären Mikrokarzinom der Schilddrüse

verfasst von: Prof. Dr. Theresia Weber

Erschienen in: Journal für Klinische Endokrinologie und Stoffwechsel | Ausgabe 4/2021

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Zusammenfassung

Die chirurgische Therapie des papillären Mikrokarzinoms der Schilddrüse (PTMC) wird zunehmend kontrovers diskutiert. Da in Japan bereits >50 % der PTMC nur beobachtet werden, fordern auch in der westlichen Welt immer mehr Ärzte eine „active surveillance“ anstelle einer (Hemi‑)Thyreoidektomie. Geeignet für eine Verlaufsbeobachtung scheinen vor allem unifokale Karzinome älterer Patienten, die kein extrathyreoidales Wachstum oder eine lymphogene Metastasierung zeigen. Erste Berechnungen einer lebenslangen Beobachtung zeigen, dass bei jungen Patienten ≤30 Jahren eine Wahrscheinlichkeit für eine Tumorprogression von über 60 % besteht. Sowohl die Entscheidung zur Operation als auch zur Beobachtung eines PTMC bedürfen einer Abwägung aller Argumente für und wider, die ausführlich mit dem Patienten besprochen und geplant werden müssen.
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Metadaten
Titel
Aktuelle Therapiestrategien beim papillären Mikrokarzinom der Schilddrüse
verfasst von
Prof. Dr. Theresia Weber
Publikationsdatum
04.11.2021
Verlag
Springer Vienna
Erschienen in
Journal für Klinische Endokrinologie und Stoffwechsel / Ausgabe 4/2021
Print ISSN: 1998-7773
Elektronische ISSN: 1998-7781
DOI
https://doi.org/10.1007/s41969-021-00149-6