01.12.2014 | case report
A severe case of esophageal ulcer causing a tight stricture despite long-term D-penicillamine treatment
Erschienen in: Wiener klinische Wochenschrift | Ausgabe 23-24/2014
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D-penicillamine has long been used in the management of rheumatic diseases due to the effects on inhibition of collagen synthesis. Herein, we report a severe case of esophageal ulcer causing a tight stricture extending through the distal esophagus despite the long-term D-penicillamine treatment in a patient with Wilson’s disease. D-penicillamine would theoretically be expected to contribute to the healing of an esophageal ulcer. However, the drug failed to have a favorable outcome, which is notable and worth reporting.
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