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Erschienen in: memo - Magazine of European Medical Oncology 1/2015

01.04.2015 | short review

A critical update on prognostic and predictive biomarkers in malignant pleural mesothelioma

verfasst von: Bahil Ghanim, MD, Mir Alireza Hoda, MD, Thomas Klikovits, MD, Balazs Dome, MD, PhD, Michael Grusch, PhD, Martin Filipits, PhD, Walter Klepetko, MD, Walter Berger, PhD, Balazs Hegedus, PhD

Erschienen in: memo - Magazine of European Medical Oncology | Ausgabe 1/2015

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Abstract

Malignant pleural mesothelioma (MPM) is a devastating and treatment-resistant disease. Currently, well-established prognostic and predictive biomarkers are rare in clinical practice, whereas there is a whole body of various MPM biomarker studies published in medical literature in the past decades. Besides well-established pathological parameters, including histological subtype, disease stage, or level of lymph node involvement, blood parameters and circulating proteins related to a proinflammatory phenotype are emerging as prognostic biomarkers. Here we provide an overview about the current status of prognostic and predictive biomarkers in MPM, with a strong emphasis on their applicability in clinical practice.
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Metadaten
Titel
A critical update on prognostic and predictive biomarkers in malignant pleural mesothelioma
verfasst von
Bahil Ghanim, MD
Mir Alireza Hoda, MD
Thomas Klikovits, MD
Balazs Dome, MD, PhD
Michael Grusch, PhD
Martin Filipits, PhD
Walter Klepetko, MD
Walter Berger, PhD
Balazs Hegedus, PhD
Publikationsdatum
01.04.2015
Verlag
Springer Vienna
Erschienen in
memo - Magazine of European Medical Oncology / Ausgabe 1/2015
Print ISSN: 1865-5041
Elektronische ISSN: 1865-5076
DOI
https://doi.org/10.1007/s12254-014-0166-4

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