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Erschienen in: memo - Magazine of European Medical Oncology 1/2015

01.04.2015 | short review

A critical update on prognostic and predictive biomarkers in malignant pleural mesothelioma

verfasst von: MD Bahil Ghanim, MD Mir Alireza Hoda, MD Thomas Klikovits, MD, PhD Balazs Dome, PhD Michael Grusch, PhD Martin Filipits, MD Walter Klepetko, PhD Walter Berger, PhD Balazs Hegedus

Erschienen in: memo - Magazine of European Medical Oncology | Ausgabe 1/2015

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Abstract

Malignant pleural mesothelioma (MPM) is a devastating and treatment-resistant disease. Currently, well-established prognostic and predictive biomarkers are rare in clinical practice, whereas there is a whole body of various MPM biomarker studies published in medical literature in the past decades. Besides well-established pathological parameters, including histological subtype, disease stage, or level of lymph node involvement, blood parameters and circulating proteins related to a proinflammatory phenotype are emerging as prognostic biomarkers. Here we provide an overview about the current status of prognostic and predictive biomarkers in MPM, with a strong emphasis on their applicability in clinical practice.
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Metadaten
Titel
A critical update on prognostic and predictive biomarkers in malignant pleural mesothelioma
verfasst von
MD Bahil Ghanim
MD Mir Alireza Hoda
MD Thomas Klikovits
MD, PhD Balazs Dome
PhD Michael Grusch
PhD Martin Filipits
MD Walter Klepetko
PhD Walter Berger
PhD Balazs Hegedus
Publikationsdatum
01.04.2015
Verlag
Springer Vienna
Erschienen in
memo - Magazine of European Medical Oncology / Ausgabe 1/2015
Print ISSN: 1865-5041
Elektronische ISSN: 1865-5076
DOI
https://doi.org/10.1007/s12254-014-0166-4

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