Head and neck cancers have for a long time been orphan cancers for any trials of individualized treatment, at least in part because the number of active cytotoxic drugs has been for a long time rather restricted.
Die Entwicklung neuer Medikamente zur Behandlung der Malaria ist ein wichtiges und herausforderndes Forschungsgebiet, da Malaria zu den wichtigsten Infektionserkrankungen gehört und der Erreger, Plasmodium falciparum, eine große Anpassungsfähigkeit besitzt.
The publication of practice changing clinical data is a rare event in the field of pancreatic cancer. In line with this general statement, oncologists attending or following the ASCO Annual Meeting 2009 were not surprised by being confronted with the study results mainly confirming the already existing evidence.
From May 29 to June 2, the American Society of Clinical Oncology (ASCO) held its annual meeting in Orlando, Florida (USA). The meeting was themed “personalizing cancer care”.
The 11th St. Gallen consensus meeting on the primary treatment of early breast cancer put a special emphasis on a tailored approach for patient subgroups, and by the selection of targetted treatments according to tumour biology.
The systemic treatment of patients with soft tissue sarcomas is an area of controversies where small progress has been made over the past years. The rarity of the disease in addition to the huge diversity of subtypes is probably to be responsible for the sometimes conflicting data obtained in clinical trials.
Colorectal cancer is a curable disease in stage II and stage III with higher cure rates if adjuvant chemotherapy is administered and that in most cases is treated with palliative intention in stage IV.
For years interest in developing new treatment strategies in SCLC has lagged behind the efforts addressing NSCLC. This trend could easily be followed during the ASCO 2009 meeting.
Mucosa-associated lymphoid tissue (MALT) lymphoma is amongst the most common lymphoma entities and comprises about 7% of all newly diagnosed NHL. Roughly 50% of all MALT lymphomas are located in the stomach, where a pathophysiological link with Helicobacter pylori (HP) with consecutive response to HP eradication therapy has been
Peripheral T-/NK-cell lymphomas/leukaemias (PTCL/L) comprise a heterogeneous group of haematopoietic tumours, which originate from mature T-/NK-cells, and constitute less than 15% of all non-Hodgkin lymphomas (NHL) in adults of the Western hemisphere.
Over 30 years ago, the combination of cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) was demonstrated to induce complete remissions and long-term disease-free survival in a considerable proportion of lymphoma patients.
Metastases of the liver are a common event in malignancies particularly of the gastrointestinal tract and a leading cause of cancer-related death. Until a few years ago, treatment for these patients was given based on palliative strategies.