Why do patients reach out for herbal medicinal products in the first
place? What is the true potential of phytopharmaceuticals and where
are their limitations? Phytopharmaceuticals are effective medicines
with low incidence of side effects.
Herbal medicinal products have been used since several decades for
the health care of children. Nevertheless, well-controlled clinical
studies with herbal medicinal products for children are rare. The
authors’ objective therefore was to evaluate clinical trials with
herbal medicinal products in children, based on a literature search in
PubMed and Web of Science.
Pharmacological research confirms and supports the clinically
observed antidepressant efficacy of St. John’s wort (Hypericum
perforatum L., SJW). This contribution is an update of a former review
by the authors in 2007.
There are numerous statements in the literature suggesting that the
safety of herbal products or herbal medicinal products is inadequately
considered. Despite the presence of risk, the potential is commonly
underestimated as herbals are considered to be natural substances.
Based on subgroup analyses of randomized, controlled clinical trials,
we review the efficacy of three phytopharmaceutical drugs,
respectively of the corresponding active substances silexan® (WS®
1265, lavender oil) in anxiety disorders, WS® 5570 (Hypericum
extract) in major depression, and EGb 761® (Ginkgo biloba extract) in
Alzheimer, vascular, or mixed type dementia, in elderly patients aged
≥ 60 years.
Background: The use of complementary and alternative medicine (CAM)
is widespread in children with cancer and is poorly regulated.
Patients and methods: Case report.
Results: We describe a case of severe cyanide poisoning arising from