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High acceptance of herbal medicinal products: What does the future hold?

07/2015 Why do patients reach out for herbal medicinal products in the first place? What is the true potential of phytopharmaceuticals and where are their limitations? Phytopharmaceuticals are effective medicines with low incidence of side effects. [...]

Clinical trials with herbal medicinal products in children: a literature analysis

07/2015 Herbal medicinal products have been used since several decades for the health care of children. Nevertheless, well-controlled clinical studies with herbal medicinal products for children are rare. The authors’ objective therefore was to evaluate clinical trials with herbal medicinal products in children, based on a literature search in PubMed and Web of Science. [...]

The mechanisms of action of St. John’s wort: an update

07/2015 Pharmacological research confirms and supports the clinically observed antidepressant efficacy of St. John’s wort (Hypericum perforatum L., SJW). This contribution is an update of a former review by the authors in 2007. [...]

Drug safety aspects of herbal medicinal products

07/2015 There are numerous statements in the literature suggesting that the safety of herbal products or herbal medicinal products is inadequately considered. Despite the presence of risk, the potential is commonly underestimated as herbals are considered to be natural substances. [...]

Phytopharmaceutical treatment of anxiety, depression, and dementia in the elderly: evidence from randomized, controlled clinical trials

07/2015 Based on subgroup analyses of randomized, controlled clinical trials, we review the efficacy of three phytopharmaceutical drugs, respectively of the corresponding active substances silexan® (WS® 1265, lavender oil) in anxiety disorders, WS® 5570 (Hypericum extract) in major depression, and EGb 761® (Ginkgo biloba extract) in Alzheimer, vascular, or mixed type dementia, in elderly patients aged ≥ 60 years. [...]

Severe cyanide poisoning from an alternative medicine treatment with amygdalin and apricot kernels in a 4-year-old child

07/2015 Background: The use of complementary and alternative medicine (CAM) is widespread in children with cancer and is poorly regulated.

Patients and methods: Case report.

Results: We describe a case of severe cyanide poisoning arising from CAM use. [...]

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