Metastatic urinary bladder transitional cell carcinoma to the oral cavity and oropharynx
Background: Distant metastasis from urinary bladder transitional cell carcinoma (TCC) is a well-reported phenomenon, most commonly occurring in osseous and pulmonary sites. In contrast, metastasis to oral and/or oropharyngeal soft tissues is extremely rare.
Methods: We present a case of a 75-year-old gentleman with treated urinary bladder TCC who presented 4 years later with a base of tongue metastasis and airway compromise necessitating a tracheostomy. A systematic review of all previously reported cases of metastatic urinary bladder TCC to the oral cavity and/or oropharynx in the English literature was performed and a summary presented.
Results: A total of six cases, including ours, of the aforementioned presentation have been reported in English literature.
Conclusions: This is the first systematic review of all previously reported cases of metastatic urinary bladder TCC to the oral cavity and/or oropharynx in the English literature. It is an extremely rare phenomenon with a uniformly dismal prognosis.