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Erschienen in: Wiener Medizinische Wochenschrift 19-20/2012

01.10.2012 | main topic

FDG PET and FDG PET/CT in patients with gastrointestinal stromal tumours

verfasst von: MD Philipp Malle, MD Manfred Sorschag, MD Hans-Jürgen Gallowitsch, Univ.-Doz.

Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 19-20/2012

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Summary

Gastrointestinal stromal tumours (GISTs) are fairly rare neoplasms, constituting less than 3 % of all gastrointestinal malignancies. The integration of molecularly targeted treatment regimes (i.e., tyrosine kinase inhibitors) in clinical oncology has revolutionized the management of patients with irresectable GISTs or metastatic disease. Malignant GISTs usually display increased glucose metabolism and therefore 18F-fluorodeoxyglucose (FDG) uptake within the scope of positron emission tomography (PET) scans. Nowadays, dual-modality FDG PET/CT (computed tomography) imaging is of considerable value in diagnostic work-up of patients with GISTs acquiring functional and anatomic information simultaneously. The following article sheds light on the impact of FDG PET and combined FDG PET/CT imaging in initial disease evaluation, detection of tumour recurrence and the early assessment of treatment response to molecularly targeted agents such as imatinib mesylate or sunitinib maleate.
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Metadaten
Titel
FDG PET and FDG PET/CT in patients with gastrointestinal stromal tumours
verfasst von
MD Philipp Malle
MD Manfred Sorschag
MD Hans-Jürgen Gallowitsch, Univ.-Doz.
Publikationsdatum
01.10.2012
Verlag
Springer Vienna
Erschienen in
Wiener Medizinische Wochenschrift / Ausgabe 19-20/2012
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI
https://doi.org/10.1007/s10354-012-0131-y

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