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Erschienen in: memo - Magazine of European Medical Oncology 2/2012

01.06.2012 | review

Interventional therapy for symptomatic bronchial carcinoma

verfasst von: Christian Geltner, M.D.

Erschienen in: memo - Magazine of European Medical Oncology | Ausgabe 2/2012

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Abstract

Symptoms such as dyspnoea, haemoptysis, coughing frequently occur in patients with bronchial carcinoma. Usually, central airway obstruction, pleural effusion or vena cava compression syndrome cause dyspnoea. Interventional bronchoscopy techniques, e.g. laser coagulation, electrocautery and cryosurgery offer very effective means for the re-canalisation of central airway obstruction. Stent placement and high-dose radiation brachytherapy are the procedures of choice for the treatment of extrinsic stenoses. The use of bronchoscopic coagulation, balloon catheters and embolisation of bronchial arteries may control severe haemoptysis. All interventional bronchoscopic techniques show symptomatic improvement and overall survival benefit in patients with bronchial carcinoma. Pleural involvement and effusion reflect progression of disease. Treatment consists of thoracoscopic talc pleurodesis and the use of various types of pleural catheters. Angiographic interventions (bronchial artery embolisation, dilatation and stenting of the vena cava superior) are needed for massive haemoptysis and the cava compression syndrome respectively.
Literatur
1.
Zurück zum Zitat Ernst A, Feller-Kopman D, Becker HD, et al. Central airway obstruction. AJRCCM. 2004;169:1278–97. Ernst A, Feller-Kopman D, Becker HD, et al. Central airway obstruction. AJRCCM. 2004;169:1278–97.
2.
Zurück zum Zitat Bollinger CT, Sutedja TG, Strausz J, et al. Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents. Eur Resp J. 2006;27:1258–71.CrossRef Bollinger CT, Sutedja TG, Strausz J, et al. Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents. Eur Resp J. 2006;27:1258–71.CrossRef
4.
Zurück zum Zitat Han CC, Prasetyo D, Wright GM. Endobronchial palliation using Nd:YAG laser is associated with improved survival when combined with multimodal adjuvant treatments. J Thorac oncol. 2007;2:59–64.CrossRefPubMed Han CC, Prasetyo D, Wright GM. Endobronchial palliation using Nd:YAG laser is associated with improved survival when combined with multimodal adjuvant treatments. J Thorac oncol. 2007;2:59–64.CrossRefPubMed
5.
Zurück zum Zitat Dutau H, Breen DP. Endobronchial laser treatment: an essential tool in therapeutic bronchoscopy. Eur Resp Mon. 2010;48:149–60.CrossRef Dutau H, Breen DP. Endobronchial laser treatment: an essential tool in therapeutic bronchoscopy. Eur Resp Mon. 2010;48:149–60.CrossRef
6.
Zurück zum Zitat Schuhmann C, Hetzel M, Babiak AJ, et al. Endobronchial tumor debulking with a flexible cryoprobe for immediate treatment of malignant stenosis. J Thorac Cardiovasc Surg. 2010;139:997.CrossRef Schuhmann C, Hetzel M, Babiak AJ, et al. Endobronchial tumor debulking with a flexible cryoprobe for immediate treatment of malignant stenosis. J Thorac Cardiovasc Surg. 2010;139:997.CrossRef
7.
Zurück zum Zitat Marasso A, Gallo E, Massiglia GM, et al. Cryosurgery in bronchoscopic treatment of tracheobronchial stenosis. Indications, limits, personal experience. Chest. 1993;103:472–4.CrossRefPubMed Marasso A, Gallo E, Massiglia GM, et al. Cryosurgery in bronchoscopic treatment of tracheobronchial stenosis. Indications, limits, personal experience. Chest. 1993;103:472–4.CrossRefPubMed
8.
Zurück zum Zitat Cavaliere S, Venuta F, Foccoli P, et al. Endoscopic treatment of malignant airway obstruction in 2008 cases. Chest. 1996;110:1536–42.CrossRefPubMed Cavaliere S, Venuta F, Foccoli P, et al. Endoscopic treatment of malignant airway obstruction in 2008 cases. Chest. 1996;110:1536–42.CrossRefPubMed
9.
Zurück zum Zitat Hetzel M, Hetzel J, Schumann C, et al. Cryorecanalization: a new approach for immediate management of tracheobronchial obstruction. J Thorac Cardivasc Surg. 2004;127:1427–31.CrossRef Hetzel M, Hetzel J, Schumann C, et al. Cryorecanalization: a new approach for immediate management of tracheobronchial obstruction. J Thorac Cardivasc Surg. 2004;127:1427–31.CrossRef
10.
Zurück zum Zitat Ernst A, Simoff M, Ost D, et al. Prospective risk-adjusted morbidity and mortality outcome analysis after therapeutic bronchoscopic procedures: results of a multi-institutional outcomes database. Chest. 2008;134:514–51.CrossRefPubMed Ernst A, Simoff M, Ost D, et al. Prospective risk-adjusted morbidity and mortality outcome analysis after therapeutic bronchoscopic procedures: results of a multi-institutional outcomes database. Chest. 2008;134:514–51.CrossRefPubMed
11.
Zurück zum Zitat Chhajed PN, Somandin S, Baty F, et al. Therapeutic bronchoscopy for malignant airway stenoses: choice of modality and survival. J Cancer Res Ther. 2010;6(2):204–9.CrossRefPubMed Chhajed PN, Somandin S, Baty F, et al. Therapeutic bronchoscopy for malignant airway stenoses: choice of modality and survival. J Cancer Res Ther. 2010;6(2):204–9.CrossRefPubMed
12.
Zurück zum Zitat Chhajed PN, Baty F, Pless M, et al. Outcome of treated advanced non-small cell lung cancer with and without central airway obstruction. Chest. 2007;130:1803–7.CrossRef Chhajed PN, Baty F, Pless M, et al. Outcome of treated advanced non-small cell lung cancer with and without central airway obstruction. Chest. 2007;130:1803–7.CrossRef
13.
Zurück zum Zitat Gudovsky LM, Koroleva NS, Biryukov YB, et al. Tracheoesophageal fistulas. Ann Thorac Surg. 1993;55:868–75.CrossRefPubMed Gudovsky LM, Koroleva NS, Biryukov YB, et al. Tracheoesophageal fistulas. Ann Thorac Surg. 1993;55:868–75.CrossRefPubMed
14.
Zurück zum Zitat Freitag L, Tekoff E, Steveling H, et al. Management of malignant esophago-tracheal fistulas with airway stenting and double stenting. Chest. 1996;110:1155–62.CrossRefPubMed Freitag L, Tekoff E, Steveling H, et al. Management of malignant esophago-tracheal fistulas with airway stenting and double stenting. Chest. 1996;110:1155–62.CrossRefPubMed
15.
Zurück zum Zitat Nag S, Kelly JF, Horton JL, et al. The American Brachytherapy Society recommendations for brachytherapy for carcinoma of the lung. Oncology. 2001;15:371–81.PubMed Nag S, Kelly JF, Horton JL, et al. The American Brachytherapy Society recommendations for brachytherapy for carcinoma of the lung. Oncology. 2001;15:371–81.PubMed
16.
Zurück zum Zitat Aumont-le Guilcher M, Prevost B, Sunyach MP, et al. High-dose-rate brachytherapy for non-small-cell lung carcinoma: a retrospective study of 226 patients. Int J Radiat Oncol Biol Phys. 2011;79:1112–16.CrossRef Aumont-le Guilcher M, Prevost B, Sunyach MP, et al. High-dose-rate brachytherapy for non-small-cell lung carcinoma: a retrospective study of 226 patients. Int J Radiat Oncol Biol Phys. 2011;79:1112–16.CrossRef
17.
Zurück zum Zitat Michailidou I, Becker HD, Eberhardt R. Bronchoscopic high dose rate brachytherapy. Eur Resp Mon. 2010;48:173–89.CrossRef Michailidou I, Becker HD, Eberhardt R. Bronchoscopic high dose rate brachytherapy. Eur Resp Mon. 2010;48:173–89.CrossRef
18.
Zurück zum Zitat Stout R, Barber P, Burt P, et al. Clinical and quality of life outcomes in the first United Kingdom randomized trialof endobronchial brachytherapy (intraluminal radiotherapy vs.external beam radiotherapy) in the palliative treatment of inoperable non-small-cell long cancer. Radiother Oncol. 2000;56:323–7.CrossRefPubMed Stout R, Barber P, Burt P, et al. Clinical and quality of life outcomes in the first United Kingdom randomized trialof endobronchial brachytherapy (intraluminal radiotherapy vs.external beam radiotherapy) in the palliative treatment of inoperable non-small-cell long cancer. Radiother Oncol. 2000;56:323–7.CrossRefPubMed
19.
Zurück zum Zitat Langendijk H, de Jong J, Tjewa M, et al. External irradiation versus external irridation plus endobronchial brachytherapy in inoperable non-small-cell lung cancer: a prospective randomized study. Radiother Oncol. 2001;58:257–68.CrossRefPubMed Langendijk H, de Jong J, Tjewa M, et al. External irradiation versus external irridation plus endobronchial brachytherapy in inoperable non-small-cell lung cancer: a prospective randomized study. Radiother Oncol. 2001;58:257–68.CrossRefPubMed
20.
Zurück zum Zitat Mal H, Rullon I, Mellot F, et al. Immediate and long-term results of bronchial artery embolization for life-threatening hemoptysis. Chest. 1999;115:996–1010.CrossRefPubMed Mal H, Rullon I, Mellot F, et al. Immediate and long-term results of bronchial artery embolization for life-threatening hemoptysis. Chest. 1999;115:996–1010.CrossRefPubMed
21.
Zurück zum Zitat Swanson KL, Johnson CM, Prakash UB, et al. Bronchial artery embolization: experience with 54 patients. Chest. 2002;121(3):789–95.CrossRefPubMed Swanson KL, Johnson CM, Prakash UB, et al. Bronchial artery embolization: experience with 54 patients. Chest. 2002;121(3):789–95.CrossRefPubMed
22.
Zurück zum Zitat Andersen PE. Imaging and interventional radiological treatment of hemoptysis. Acta Radiol. 2006;47:780–92.CrossRefPubMed Andersen PE. Imaging and interventional radiological treatment of hemoptysis. Acta Radiol. 2006;47:780–92.CrossRefPubMed
23.
Zurück zum Zitat Musani AI, Treatment options for maligant pleural effusion. Curr Opin Pulm Med. 2009;15:380–7CrossRefPubMed Musani AI, Treatment options for maligant pleural effusion. Curr Opin Pulm Med. 2009;15:380–7CrossRefPubMed
24.
Zurück zum Zitat Janssen JP, Collier G, Astoul P. Safety of pleurodesis with talc poudrage in malignant pleural effusion: a prospective cohort study. Lancet. 2007;369:1535–9.CrossRefPubMed Janssen JP, Collier G, Astoul P. Safety of pleurodesis with talc poudrage in malignant pleural effusion: a prospective cohort study. Lancet. 2007;369:1535–9.CrossRefPubMed
25.
Zurück zum Zitat Musani AI, Haas AR, Seijo L. Outpatient management of malignant pleural effusions with small-bore, tunneled pleural catheters. Respiration. 2004 (Nov–Dec);71(6):559–66. Musani AI, Haas AR, Seijo L. Outpatient management of malignant pleural effusions with small-bore, tunneled pleural catheters. Respiration. 2004 (Nov–Dec);71(6):559–66.
26.
Zurück zum Zitat Watkinson AF, Yeow TN, Fraser C. Endovascular stenting to treat obstruction of the superior vena cava. BMJ. 2008;21:(336 (7658)):1434–7.CrossRef Watkinson AF, Yeow TN, Fraser C. Endovascular stenting to treat obstruction of the superior vena cava. BMJ. 2008;21:(336 (7658)):1434–7.CrossRef
Metadaten
Titel
Interventional therapy for symptomatic bronchial carcinoma
verfasst von
Christian Geltner, M.D.
Publikationsdatum
01.06.2012
Verlag
Springer Vienna
Erschienen in
memo - Magazine of European Medical Oncology / Ausgabe 2/2012
Print ISSN: 1865-5041
Elektronische ISSN: 1865-5076
DOI
https://doi.org/10.1007/s12254-012-0002-7

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