The basis underlying the toxicities of immune checkpoint inhibitors
is their promotion of T-cell activity in a physiological manner.
“The amplification of the immune system results in autoimmunity,”
explained Ross Soo, MD, FRACP, National University Cancer Institute,
Common AEs include fatigue, anorexia and arthralgia. Terms that
denote immune-related adverse events (irAEs) typically end in -itis or