Hypertension and coronary artery disease: epidemiology, physiology, effects of treatment, and recommendations
A joint scientific statement from the Austrian Society of Cardiology and the Austrian Society of Hypertension
High blood pressure is a major modifiable risk factor for all clinical manifestations of coronary artery disease (CAD). In people without known cardiovascular disease, the lowest systolic (down to 90–114 mmHg) and the lowest diastolic (down to 60–74 mmHg) pressures are associated with the lowest risk for developing CAD. Although diastolic blood pressure is the strongest predictor of CAD in younger and middle-aged people, this relationship becomes inverted and pulse pressure shows the strongest direct relationship with CAD in people above 60 years of age.