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Erschienen in: Wiener klinische Wochenschrift 9-10/2014

01.05.2014 | case report

Diffuse nodular lymphoid hyperplasia of the small bowel associated with common variable immunodeficiency and giardiasis: a rare case report

verfasst von: Dr. Sehmus Olmez, Mehmet Aslan, Alpaslan Yavuz, Gulay Bulut, Ahmet Cumhur Dulger

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 9-10/2014

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Summary

Diffuse nodular lymphoid hyperplasia (DNLH) of the intestine is an extremely rare lymphoproliferative disorder of uncertain etiology. Typically, numerous polypoid nodules composed of hyperplastic benign lymphoid tissue are present in the small and/or large intestinal mucosa. DNLH has been observed in association with common variable immunodeficiency (CVID). A 38-years-old man was admitted to our clinic due to dyspeptic complaints. An upper gastrointestinal system endoscopic examination revealed DNLH in the duodenum. A biopsy specimen showed the presence of nodular lymphoid hyperplasia and a Giardia lamblia infection in the duodenum. CVID was suspected, and the diagnosis was established by demonstrating a significant reduction in the serum gamma-globulin levels. DNLH is a rare benign condition with regards to diagnosis and treatment of unknown etiology. In patients with DNLH, screening for the immune deficiencies is being important in addition to histopathological examinations.
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Metadaten
Titel
Diffuse nodular lymphoid hyperplasia of the small bowel associated with common variable immunodeficiency and giardiasis: a rare case report
verfasst von
Dr. Sehmus Olmez
Mehmet Aslan
Alpaslan Yavuz
Gulay Bulut
Ahmet Cumhur Dulger
Publikationsdatum
01.05.2014
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 9-10/2014
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-014-0525-5

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