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Gastroenterologie 31. Oktober 2009

Obscure gastrointestinal bleeding

Hypochromic, microcytic anaemia due to iron deficiency is usually caused by blood loss due to gynaecologic or gastrointestinal diseases. If no source of bleeding can be found using routine endoscopy and gynaecologic evaluation, a more detailed diagnostic workup must be performed before iron supplementation “ex juvantibus” is initiated. Here, we present a patient with progressive iron deficiency anaemia despite iron supplementation caused by bleeding due to infiltration of the small intestine by a diffuse large B-cell lymphoma. The diagnostic workup as well as the differential diagnosis and therapeutic approach in such rare cases will be outlined.

Ella Willenbacher, Johanna Kantner, Walpurga Weyrer, David Nachbaur, Rupert Prommegger, Ulrich Strasser, Hubert Schwaighofer, Eberhard Gunsilius, memo - Magazine of European Medical Oncology 3/2009

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