Skip to main content
Erschienen in: Wiener klinische Wochenschrift 2/2012

01.12.2012 | leitlinien für die praxis

Positionspapier: Psychische Erkrankungen und Diabetes mellitus

verfasst von: Heidemarie Abrahamian, Alexandra Kautzky-Willer, Angelika Rießland-Seifert, Peter Fasching, Christoph Ebenbichler, Peter Hofmann, Hermann Toplak

Erschienen in: Wiener klinische Wochenschrift | Sonderheft 2/2012

Einloggen, um Zugang zu erhalten

Zusammenfassung

Diabetes mellitus ist häufig mit psychischen Erkrankungen assoziiert. Depressive Störungen kommen bei diabetischen Patienten doppelt so häufig vor wie in der nicht-diabetischen Population. Andere psychische Erkrankungen die gehäuft mit Diabetes mellitus vorkommen sind auffälliges Essverhalten, Angststörungen, Schizophrenie und borderline Persönlichkeitsstörung. Die ungünstigen Auswirkungen dieser Koinzidenz auf den Stoffwechsel sind nachhaltig und manifestieren als schlechtere metabolische Kontrolle und vermehrte mikro- und makroangipathische Komplikationen. Ziel dieses Positionspapieres ist sowohl die Sensibilisierung aller involvierten medizinischen FachkollegInnen sowie sonstiger mit dem Thema befasster Berufsgruppen und Organisationen als auch die Intensivierung der komplexen therapeutischen Interventionen bei PatientInnen. Positive Auswirkungen wären die konsekutive Reduktion von Spätfolgen, insbesondere der kardiovaskulären Morbidität und Mortalität sowie eine verbesserte Lebensqualität der Betroffenen.
Literatur
1.
Zurück zum Zitat De Hert M, Dekker JM, Wood D, Kahl KG, Holt RIG, Möller HJ. Cardiovascular disease and diabetes in people with severe mental illness position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC). Eur Psychiatry. 2009;24(6):412–24.PubMedCrossRef De Hert M, Dekker JM, Wood D, Kahl KG, Holt RIG, Möller HJ. Cardiovascular disease and diabetes in people with severe mental illness position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC). Eur Psychiatry. 2009;24(6):412–24.PubMedCrossRef
2.
Zurück zum Zitat De Hert M, Dobbelaere M, Sheridan EM, Cohen D, Correll CU. Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: a systematic review of randomized, placebo controlled trials and guidelines for clinical practice. Eur Psychiatry. 2011;26(3):144–58.PubMedCrossRef De Hert M, Dobbelaere M, Sheridan EM, Cohen D, Correll CU. Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: a systematic review of randomized, placebo controlled trials and guidelines for clinical practice. Eur Psychiatry. 2011;26(3):144–58.PubMedCrossRef
3.
Zurück zum Zitat Smith M, Hopkins D, Peveler RC, Holt RI, Woodward M, Ismail K. First- v. second-generation antipsychotics and risk for diabetes in schizophrenia: systematic review and metaanalysis. Br J Psychiatry. 2008;192(6):406–11.PubMedCrossRef Smith M, Hopkins D, Peveler RC, Holt RI, Woodward M, Ismail K. First- v. second-generation antipsychotics and risk for diabetes in schizophrenia: systematic review and metaanalysis. Br J Psychiatry. 2008;192(6):406–11.PubMedCrossRef
4.
Zurück zum Zitat Katon W, Ming-Yu F, Unützer J, Taylor J, Pincus H, Schoenbaum M. Depression and diabetes: a potentially lethal combination. J Gen Intern Med. 2008;23(10):1571–5.PubMedCrossRef Katon W, Ming-Yu F, Unützer J, Taylor J, Pincus H, Schoenbaum M. Depression and diabetes: a potentially lethal combination. J Gen Intern Med. 2008;23(10):1571–5.PubMedCrossRef
5.
Zurück zum Zitat Sullivan MD, O`Connor P, Feeney P, Hire D, Simmons DL, et al. Depression predicts all-cause mortality. Epidemiological evaluation from the ACCORD HRQL substudy. Diabetes Care. 2012;35:1708–15.PubMedCrossRef Sullivan MD, O`Connor P, Feeney P, Hire D, Simmons DL, et al. Depression predicts all-cause mortality. Epidemiological evaluation from the ACCORD HRQL substudy. Diabetes Care. 2012;35:1708–15.PubMedCrossRef
6.
Zurück zum Zitat Anderson RJ, Freedland KE, Clouse RE, Lustman PJ. The prevalence of comorbid depression in adults with diabetes. Diabetes Care. 2001;24:1069–78.PubMedCrossRef Anderson RJ, Freedland KE, Clouse RE, Lustman PJ. The prevalence of comorbid depression in adults with diabetes. Diabetes Care. 2001;24:1069–78.PubMedCrossRef
7.
Zurück zum Zitat Abrahamian H, Hofmann P, Prager R, Toplak H. Diabetes mellitus and co-morbid depression: treatment with milnacipran results in significant improvement of both diseases (results from the Austrian MDDM study group). Neuropsychiatr Dis Treat. 2009;5:261–6.PubMedCrossRef Abrahamian H, Hofmann P, Prager R, Toplak H. Diabetes mellitus and co-morbid depression: treatment with milnacipran results in significant improvement of both diseases (results from the Austrian MDDM study group). Neuropsychiatr Dis Treat. 2009;5:261–6.PubMedCrossRef
8.
Zurück zum Zitat Knol MJ, Twisk JWR, Beekman ATF, Heine RJ, Snoek FJ, Pouwer F. Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis. Diabetologia. 2006;49:837–45.PubMedCrossRef Knol MJ, Twisk JWR, Beekman ATF, Heine RJ, Snoek FJ, Pouwer F. Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis. Diabetologia. 2006;49:837–45.PubMedCrossRef
9.
Zurück zum Zitat Ali S, Stone A, Peters L, Davies MJ, Khunti K. The prevalence of co-morbid depression in adults with type 2 diabetes: a systematic review and meta-analysis. Diabet Med. 2006;23:1165–73.PubMedCrossRef Ali S, Stone A, Peters L, Davies MJ, Khunti K. The prevalence of co-morbid depression in adults with type 2 diabetes: a systematic review and meta-analysis. Diabet Med. 2006;23:1165–73.PubMedCrossRef
10.
Zurück zum Zitat Gonzalez JS, Delahanty LM, Safren SA, Meigs JB, Grant RW. Differentiating symptoms of depression from diabetes-specific distress: relationships with self-care in type 2 diabetes. Diabetologia. 2008;51(10):1822–5.PubMedCrossRef Gonzalez JS, Delahanty LM, Safren SA, Meigs JB, Grant RW. Differentiating symptoms of depression from diabetes-specific distress: relationships with self-care in type 2 diabetes. Diabetologia. 2008;51(10):1822–5.PubMedCrossRef
11.
Zurück zum Zitat Whooley MA, Avins AL, Miranda J, et al. Case-finding instrument for depression. J Gen Intern Med. 1997;12:439–45.PubMedCrossRef Whooley MA, Avins AL, Miranda J, et al. Case-finding instrument for depression. J Gen Intern Med. 1997;12:439–45.PubMedCrossRef
13.
Zurück zum Zitat Sayuk GS, Gott BM, Nix BD, Lustman PJ. Improvement in sexual functioning in patients with type 2 diabetes and depression treated with bupropion. Diabetes Care. 2011;34(2):332–4.PubMedCrossRef Sayuk GS, Gott BM, Nix BD, Lustman PJ. Improvement in sexual functioning in patients with type 2 diabetes and depression treated with bupropion. Diabetes Care. 2011;34(2):332–4.PubMedCrossRef
14.
Zurück zum Zitat Collins MM, Corcoran P, Perry IJ. Anxiety and depression symptoms in patients with diabetes. Diabet Med. 2009;26(2):153–61.PubMedCrossRef Collins MM, Corcoran P, Perry IJ. Anxiety and depression symptoms in patients with diabetes. Diabet Med. 2009;26(2):153–61.PubMedCrossRef
15.
Zurück zum Zitat Ludman E, Katon W, Russo J, Simon G, Lin EH, Ciechanowski P, Von Korff M, Young B. Panic episodes among patients with diabetes. Gen Hosp Psychiatry. 2006;28: 475–81.PubMedCrossRef Ludman E, Katon W, Russo J, Simon G, Lin EH, Ciechanowski P, Von Korff M, Young B. Panic episodes among patients with diabetes. Gen Hosp Psychiatry. 2006;28: 475–81.PubMedCrossRef
16.
Zurück zum Zitat Young-Hyman DL, Davis CL. Disordered eating behavior in individuals with diabetes. Diabetes Care. 2010;33: 683–9.PubMedCrossRef Young-Hyman DL, Davis CL. Disordered eating behavior in individuals with diabetes. Diabetes Care. 2010;33: 683–9.PubMedCrossRef
17.
Zurück zum Zitat Markowitz JT, Butler DA, Vokening LK, Antisdel JE, Anderson BJ, et al. Brief screening tool for disordered eating in diabetes: internal consistency and external validity in a contemporary sample of pediatric patients with type 1 diabetes. Diabetes Care. 2010;33:495–500.PubMedCrossRef Markowitz JT, Butler DA, Vokening LK, Antisdel JE, Anderson BJ, et al. Brief screening tool for disordered eating in diabetes: internal consistency and external validity in a contemporary sample of pediatric patients with type 1 diabetes. Diabetes Care. 2010;33:495–500.PubMedCrossRef
18.
Zurück zum Zitat Mai Qu, Holman CDÀrcy, Sanfilippo FM, Emery JD, Preen DB. Mental illness related disparities in diabetes prevalence, quality of care and outcomes: a population-based longitudinal study. BMC Med. 2011;9:118.PubMedCrossRef Mai Qu, Holman CDÀrcy, Sanfilippo FM, Emery JD, Preen DB. Mental illness related disparities in diabetes prevalence, quality of care and outcomes: a population-based longitudinal study. BMC Med. 2011;9:118.PubMedCrossRef
19.
Zurück zum Zitat Kahl KG, Greggersen W, Schweiger U, Cordes J, Correll CU, Frieling H, et al. Prevalence of the metabolic syndrome in patients with borderline personality disorder: results from a cross-sectional study. Eur Arch Psychol Clin Neurosci. 2012 Jul 10. [Epub ahead of print]. Kahl KG, Greggersen W, Schweiger U, Cordes J, Correll CU, Frieling H, et al. Prevalence of the metabolic syndrome in patients with borderline personality disorder: results from a cross-sectional study. Eur Arch Psychol Clin Neurosci. 2012 Jul 10. [Epub ahead of print].
20.
Zurück zum Zitat Goff DC, Sullivan LM, McEvoy JP, Meyer J, Nasrallah H, Daumit G, et al. A comparison of ten-year cardiac risk estimates in schizophrenia patients from the CATIE study and matched controls. Schizophr Res. 2005;80(1):45–53.PubMedCrossRef Goff DC, Sullivan LM, McEvoy JP, Meyer J, Nasrallah H, Daumit G, et al. A comparison of ten-year cardiac risk estimates in schizophrenia patients from the CATIE study and matched controls. Schizophr Res. 2005;80(1):45–53.PubMedCrossRef
21.
Zurück zum Zitat Jones BJ, Gallagher BJ, Moss DM, McFalls JA. Obstetrical complications, social class and type of schizophrenia. Clin Schizophr Relat Psychoses. 2011;5(1):33–9.PubMedCrossRef Jones BJ, Gallagher BJ, Moss DM, McFalls JA. Obstetrical complications, social class and type of schizophrenia. Clin Schizophr Relat Psychoses. 2011;5(1):33–9.PubMedCrossRef
22.
Zurück zum Zitat Beumer W, Drexhage RC, De Wit H, Versnel MA, Drexhage HA, Cohen D. Increased level of serum cytokines, chemokines and adipokines in patients with schizophrenia is associated with disease and metabolic syndrome. Psychoneuroendocrinology. 2012 Apr 26, [Epub ahead of print]. Beumer W, Drexhage RC, De Wit H, Versnel MA, Drexhage HA, Cohen D. Increased level of serum cytokines, chemokines and adipokines in patients with schizophrenia is associated with disease and metabolic syndrome. Psychoneuroendocrinology. 2012 Apr 26, [Epub ahead of print].
23.
Zurück zum Zitat Ress C, Tschoner A, Kaser S, Ebenbichler C. Psychopharmaka und Diabetes. Wien Med Wochenschr. 2011;161(21–22):531–42.PubMedCrossRef Ress C, Tschoner A, Kaser S, Ebenbichler C. Psychopharmaka und Diabetes. Wien Med Wochenschr. 2011;161(21–22):531–42.PubMedCrossRef
24.
Zurück zum Zitat Bushe CJ, Leonard BE. Blood glucose and schizophrenia – a systematic review of prospective randomized clinical trials. J Clin Psychiatry. 2007;68(11):1682–90.PubMedCrossRef Bushe CJ, Leonard BE. Blood glucose and schizophrenia – a systematic review of prospective randomized clinical trials. J Clin Psychiatry. 2007;68(11):1682–90.PubMedCrossRef
25.
Zurück zum Zitat Prisciandaro JJ, Gebregziabher M, Grubaugh AL, Gilbert GE, Echols C, Egede LE. Impact of psychiatric comorbidity on mortality in veterans with type 2 diabetes. Diabetes Technol Ther. 2011;13(1):73–8.PubMedCrossRef Prisciandaro JJ, Gebregziabher M, Grubaugh AL, Gilbert GE, Echols C, Egede LE. Impact of psychiatric comorbidity on mortality in veterans with type 2 diabetes. Diabetes Technol Ther. 2011;13(1):73–8.PubMedCrossRef
26.
27.
Zurück zum Zitat Delamater AM, Jacobson AM, Anderson B, Cox D, Fisher L, et al. Improving patient adherence. Clin Diab. 2006;24(2):71–7.CrossRef Delamater AM, Jacobson AM, Anderson B, Cox D, Fisher L, et al. Improving patient adherence. Clin Diab. 2006;24(2):71–7.CrossRef
28.
Zurück zum Zitat Norris SL, Engelgau MM, Narayan KM. Effectiveness of self-management training in type 2 diabetes. Diabetes Care. 2001;24:561–8PubMedCrossRef Norris SL, Engelgau MM, Narayan KM. Effectiveness of self-management training in type 2 diabetes. Diabetes Care. 2001;24:561–8PubMedCrossRef
29.
30.
Zurück zum Zitat Roberts SE, Goldacre MJ, Neil H. Mortality in young people admitted to hospital for diabetes: database study. BMJ. 2004;328(7442):741–2.PubMedCrossRef Roberts SE, Goldacre MJ, Neil H. Mortality in young people admitted to hospital for diabetes: database study. BMJ. 2004;328(7442):741–2.PubMedCrossRef
31.
Zurück zum Zitat Von Mach MA, Gauer M, Meyer S, Omogbehin B, Schinzel H. Antidiabetic medications in overdose: a comparison of the inquiries made to a regional poisons unit regarding original sulfonylureas, biguanides and insulin. Int J Clin Pharmacol Ther. 2006;44(2):51–4.PubMed Von Mach MA, Gauer M, Meyer S, Omogbehin B, Schinzel H. Antidiabetic medications in overdose: a comparison of the inquiries made to a regional poisons unit regarding original sulfonylureas, biguanides and insulin. Int J Clin Pharmacol Ther. 2006;44(2):51–4.PubMed
32.
Zurück zum Zitat Lustmann PJ, Griffith LS, Freedland KE, Kissel SS, Clouse RE. Cognitive behaviour therapy for depression in type 2 diabetes mellitus. A randomized controlled trial. Ann Intern Med. 1998;129(8):613–21. Lustmann PJ, Griffith LS, Freedland KE, Kissel SS, Clouse RE. Cognitive behaviour therapy for depression in type 2 diabetes mellitus. A randomized controlled trial. Ann Intern Med. 1998;129(8):613–21.
33.
Zurück zum Zitat Bogner HR, Morales KH, de Vries HF, Cappola AR. Integrated management of type 2 diabetes mellitus and depression treatment to improve medication adherence: a randomized controlled trial. Ann Fam Med. 2012;10(1):15–22.PubMedCrossRef Bogner HR, Morales KH, de Vries HF, Cappola AR. Integrated management of type 2 diabetes mellitus and depression treatment to improve medication adherence: a randomized controlled trial. Ann Fam Med. 2012;10(1):15–22.PubMedCrossRef
34.
Zurück zum Zitat Markowitz S, Gonzalez JS, Wilkinson JL, Safren SA. Treating depression in diabetes: emerging findings. Psychosomatics. 2011;52:1–18.PubMedCrossRef Markowitz S, Gonzalez JS, Wilkinson JL, Safren SA. Treating depression in diabetes: emerging findings. Psychosomatics. 2011;52:1–18.PubMedCrossRef
35.
Zurück zum Zitat Georgiades A, Zucker N, Friedman KE, Mosunic CJ, Applegate K, et al. Changes in depressive symptoms and glycemic control in diabetes mellitus. Psychosom Med. 2007;69(3):235–41.PubMedCrossRef Georgiades A, Zucker N, Friedman KE, Mosunic CJ, Applegate K, et al. Changes in depressive symptoms and glycemic control in diabetes mellitus. Psychosom Med. 2007;69(3):235–41.PubMedCrossRef
36.
Zurück zum Zitat Steed L, Cooke D, Newman S. A systematic review of psychosocial outcomes following education, self-management and psychological interventions in diabetes mellitus. Patient Educ Couns. 2003;51(1):5–15.PubMedCrossRef Steed L, Cooke D, Newman S. A systematic review of psychosocial outcomes following education, self-management and psychological interventions in diabetes mellitus. Patient Educ Couns. 2003;51(1):5–15.PubMedCrossRef
37.
Zurück zum Zitat Wang MY, Tsai PS, Chou KR, Chen CM. A systematic review of the efficacy of non-pharmacological treatments for depression on glycemic control in type 2 diabetics. J Clin Nurs. 2008;17(19):2524–30.PubMedCrossRef Wang MY, Tsai PS, Chou KR, Chen CM. A systematic review of the efficacy of non-pharmacological treatments for depression on glycemic control in type 2 diabetics. J Clin Nurs. 2008;17(19):2524–30.PubMedCrossRef
38.
Zurück zum Zitat Saha S, Chant D, McGrath J. A systematic review of mortality in schizophrenia. Arch Gen Psychiatry. 2007;46:1123–31.CrossRef Saha S, Chant D, McGrath J. A systematic review of mortality in schizophrenia. Arch Gen Psychiatry. 2007;46:1123–31.CrossRef
39.
Zurück zum Zitat NICE. Schizophrenia: core intervention in the treatment and management of schizophrenia in adults in primary and secondary care. 2008. http://www.nice.org.uk/guidance/index.jsp?action=download&o=42139. Zugegriffen: 23 Aug. 2012. NICE. Schizophrenia: core intervention in the treatment and management of schizophrenia in adults in primary and secondary care. 2008. http://​www.​nice.​org.​uk/​guidance/​index.​jsp?​action=​download&​o=​42139.​ Zugegriffen: 23 Aug. 2012.
Metadaten
Titel
Positionspapier: Psychische Erkrankungen und Diabetes mellitus
verfasst von
Heidemarie Abrahamian
Alexandra Kautzky-Willer
Angelika Rießland-Seifert
Peter Fasching
Christoph Ebenbichler
Peter Hofmann
Hermann Toplak
Publikationsdatum
01.12.2012
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe Sonderheft 2/2012
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-012-0279-x

Weitere Artikel der Sonderheft 2/2012

Wiener klinische Wochenschrift 2/2012 Zur Ausgabe

leitlinien für die praxis

Insulintherapie bei Diabetes mellitus