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Innere Medizin 1. Juni 2008

A supratentorial primitive neuroectodermal tumour (sPNET) WHO IV with lymphnode metastasis: a case r

Supratentorial primitive neuroectodermal tumours (sPNET) are rare tumours in adults. Five-years survival remains below 50%. We present a case report of a 38-year-old female with metastases of a supratentorial primitive neuroectodermal tumour. Treatment was radical surgical resection, followed by chemotherapy according to the HIT 2000 protocol. Twelve months after the first diagnosis, a relapse was diagnosed which was again surgically removed followed by radiotherapy and concomitant Temozolemide. Because of severe thrombocytopenia the chemotherapy was shifted to Gleevec therapy resulting in a stable disease until now.

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