The long-term use of novel antipsoriatic systemic biotechnological
drugs may increase susceptibility to opportunistic infections. Several
cases of visceral leishmaniasis have been reported in immunosuppressed
individuals, including those who have been treated with tumour
necrosis factor alpha (TNFα) blocking agents.
First report in the medical literature
A 67-year-old woman presented with a firm plaque in the perineal
region, 16 months after diagnosis of a high-grade basaloid squamous
cell carcinoma of the vagina and treatment by external beam radiation
therapy and vaginal cuff brachytherapy.
Trombiculiasis represents a striking emerging infestation in humans.
In fact, modified lifestyles and easy and quick traveling around the
globe, together with the altered ecology and habits of the parasite
Neotrombicula autumnalis, make this original epizoonosis an
extraordinary example of synanthropic dermatosis.
Terra firma-forme dermatosis (TFFD) belongs to the group of “dirty
dermatoses” and represents a not well-known and surely
underestimated vexing skin condition. Firstly described by Duncan,
Tschen and Knox in 1987, it accounts for a few case series in the
literature and has a still undefined aetiology.
Botulinum toxin A and soft tissue fillers are cornerstones of facial
rejuvenation procedures. They can also be of benefit in facial
rehabilitation. We report on three female patients who were treated
with botulinum toxin A and/or hyaluronic acid-based fillers, one
after orthognathic surgery, two after Bell’s palsy, to correct
facial asymmetries and loss of volume to restore facial attractiveness
and improve their self-esteem and quality of life.
The achievements of contemporary medical science, diagnostics and
therapy as well as the global experience gained in recent decades have
led to an entirely new era in the understanding and practice of
medicine in all its fields worldwide.