Skip to main content
Erschienen in: memo - Magazine of European Medical Oncology 3/2015

01.09.2015 | Case report

A 59-year-old patient with somatic type malignancy as a relapse of testicular tumor after 28 years

A patient with somatic type malignancy

verfasst von: Andreas Edwin Juarso, MD, Malte Kiehl, MD, Olaf Pfennig, MD, Günther Wittenberg, MD, Florian Weissinger, MD

Erschienen in: memo - Magazine of European Medical Oncology | Ausgabe 3/2015

Einloggen, um Zugang zu erhalten

Abstract

A 59-year-old patient presented in the outpatient clinic because of an increasing mass in his right buttock. He has a history of a testicular tumor 28 years ago, with increased tumor markers (Human Choriongonadotropin (β-HCG) value 4.9 and Alpha-1 Fetoprotein (AFP) 218 ng/ml).
Literatur
1.
Zurück zum Zitat Collins DH, Pugh RC. Classification and frequency of testicular tumours. Br J Urol. 1964;36:1–11.CrossRefPubMed Collins DH, Pugh RC. Classification and frequency of testicular tumours. Br J Urol. 1964;36:1–11.CrossRefPubMed
2.
Zurück zum Zitat Winter E, Kliesch S, Souchon R, de Maike W. Diagnosis of testicular cancer. Dtsch Arztebl. 2005;102:A 3021–5 (Heft 44). Winter E, Kliesch S, Souchon R, de Maike W. Diagnosis of testicular cancer. Dtsch Arztebl. 2005;102:A 3021–5 (Heft 44).
3.
Zurück zum Zitat Ulbright TM. Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. Mod Pathol. 2005;18 Suppl 2:S61–79.CrossRefPubMed Ulbright TM. Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. Mod Pathol. 2005;18 Suppl 2:S61–79.CrossRefPubMed
4.
Zurück zum Zitat Stamatiou K, Papadopoulos P, Perlepes G, Galariotis N, Olympitis M, Moschouris H, Vasilakaki T. Mixed germ tumor of the testicle with ravdomuosarcomatous component: a case report. Cases J. 2009;2:9299.PubMedCentralCrossRefPubMed Stamatiou K, Papadopoulos P, Perlepes G, Galariotis N, Olympitis M, Moschouris H, Vasilakaki T. Mixed germ tumor of the testicle with ravdomuosarcomatous component: a case report. Cases J. 2009;2:9299.PubMedCentralCrossRefPubMed
5.
Zurück zum Zitat Krege S, et al. European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus Group (EGCCCG): part I. Eur Urol. 2008;53(3):478–96.CrossRefPubMed Krege S, et al. European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus Group (EGCCCG): part I. Eur Urol. 2008;53(3):478–96.CrossRefPubMed
6.
Zurück zum Zitat Hanna NH, Einhorn LH. Testicular cancer—discoveries and updates. N Engl J Med. 2014;371:2005–16.CrossRefPubMed Hanna NH, Einhorn LH. Testicular cancer—discoveries and updates. N Engl J Med. 2014;371:2005–16.CrossRefPubMed
7.
Zurück zum Zitat Krege S, Albers P, Schmidberger H. Treatment of non-metastatic and moderate metastatic testicular cancer. Dtsch Arztebl. 2005;102:A 3191–4 (Heft 46). Krege S, Albers P, Schmidberger H. Treatment of non-metastatic and moderate metastatic testicular cancer. Dtsch Arztebl. 2005;102:A 3191–4 (Heft 46).
8.
Zurück zum Zitat Bokemeyer C, Beyer J, Heidenreich A. Treatment of patients with metastatic germ cell tumors. Dtsch Arztebl. 2005;102:A 3271–5 (Heft 47). Bokemeyer C, Beyer J, Heidenreich A. Treatment of patients with metastatic germ cell tumors. Dtsch Arztebl. 2005;102:A 3271–5 (Heft 47).
9.
Zurück zum Zitat Pottek TS, Hartmann M, Bokemeyer C. Aftercare and delayed toxicity of testicular cancer. Dtsch Arztebl. 2005;102:A 3342–8 (Heft 48). Pottek TS, Hartmann M, Bokemeyer C. Aftercare and delayed toxicity of testicular cancer. Dtsch Arztebl. 2005;102:A 3342–8 (Heft 48).
10.
Zurück zum Zitat Gerl A, Clemm C, Schmeller N, Hentrich M, Lamerz R, Wilmanns W. Late relapse of germ cell tumors after cisplatin-based chemotherapy. Ann Oncol. 1997;8(1):41–7.CrossRefPubMed Gerl A, Clemm C, Schmeller N, Hentrich M, Lamerz R, Wilmanns W. Late relapse of germ cell tumors after cisplatin-based chemotherapy. Ann Oncol. 1997;8(1):41–7.CrossRefPubMed
11.
Zurück zum Zitat Oldenburg J, Alfsen GC, Waehre H, Fossá SD. Late recurrences of germ cell malignancies: a population-based experience over three decades. Br J Cancer. 2006;94(6):820–7.PubMedCentralCrossRefPubMed Oldenburg J, Alfsen GC, Waehre H, Fossá SD. Late recurrences of germ cell malignancies: a population-based experience over three decades. Br J Cancer. 2006;94(6):820–7.PubMedCentralCrossRefPubMed
12.
Zurück zum Zitat Geldart TR, Gale J, McKendrick J, Kirby J, Mead G. Late relapse of metastatic testicular nonseminomatous germ cell cancer: surgery is needed for cure. BJU Int. 2006;98(2):353–8.CrossRefPubMed Geldart TR, Gale J, McKendrick J, Kirby J, Mead G. Late relapse of metastatic testicular nonseminomatous germ cell cancer: surgery is needed for cure. BJU Int. 2006;98(2):353–8.CrossRefPubMed
13.
Zurück zum Zitat Ronnen EA, Kondagunta GV, Bacik J, Marion S, Bajorin DF, Sheinfeld J, Bosl GJ, Motzer RJ. Incidence of late-relapse germ cell tumor and outcome to salvage chemotherapy. J Clin Oncol. 2005;23(28):6999–7004.CrossRefPubMed Ronnen EA, Kondagunta GV, Bacik J, Marion S, Bajorin DF, Sheinfeld J, Bosl GJ, Motzer RJ. Incidence of late-relapse germ cell tumor and outcome to salvage chemotherapy. J Clin Oncol. 2005;23(28):6999–7004.CrossRefPubMed
14.
Zurück zum Zitat Krege S, et al. European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus Group (EGCCCG): part II. Eur Urol. 2008;53(3):497–513.CrossRefPubMed Krege S, et al. European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus Group (EGCCCG): part II. Eur Urol. 2008;53(3):497–513.CrossRefPubMed
15.
Zurück zum Zitat Arafat W, Albany C, Ulbright TM, Foster R, Einhorn LH. Very late relapse of germ cell tumor as a teratoma: a case report and review of the literature. J Surg Case Rep. 2014;2014(6):rju051.PubMedCentralCrossRefPubMed Arafat W, Albany C, Ulbright TM, Foster R, Einhorn LH. Very late relapse of germ cell tumor as a teratoma: a case report and review of the literature. J Surg Case Rep. 2014;2014(6):rju051.PubMedCentralCrossRefPubMed
16.
Zurück zum Zitat Pavic M, Meeus P, Treilleux I, Droz JP. Malignant teratoma 32 years after treatment of germ cell tumor confined to testis. Urology. 2006;67(4):846.CrossRefPubMed Pavic M, Meeus P, Treilleux I, Droz JP. Malignant teratoma 32 years after treatment of germ cell tumor confined to testis. Urology. 2006;67(4):846.CrossRefPubMed
18.
Zurück zum Zitat Bilici A, Ustaalioglu BB, Seker M, Kayahan S. Soft tissue metastasis from immature teratoma of the testis: second case report and review of the literature. Clin Orthop Relat Res. 2010;468(9):2541–4.PubMedCentralCrossRefPubMed Bilici A, Ustaalioglu BB, Seker M, Kayahan S. Soft tissue metastasis from immature teratoma of the testis: second case report and review of the literature. Clin Orthop Relat Res. 2010;468(9):2541–4.PubMedCentralCrossRefPubMed
19.
Zurück zum Zitat Oosterhuis JW, Peeters SH, Smit VT, Stoop H, Looijenga LH, Elzevier HW, Osanto S. Patient with two secondary somatic-type malignancies in a late recurrence of a testicular non-seminoma: illustration of potential and flaw of the cancer stem cell therapy concept. Int J Dev Biol. 2013;57(2–4):153–7.CrossRefPubMed Oosterhuis JW, Peeters SH, Smit VT, Stoop H, Looijenga LH, Elzevier HW, Osanto S. Patient with two secondary somatic-type malignancies in a late recurrence of a testicular non-seminoma: illustration of potential and flaw of the cancer stem cell therapy concept. Int J Dev Biol. 2013;57(2–4):153–7.CrossRefPubMed
20.
Zurück zum Zitat Zeh N, Wild PJ, Bode PK, Kristiansen G, Moch H, Sulser T, Hermanns T. Retroperitoneal teratoma with somatic malignant transformation: a papillary renal cell carcinoma in a testicular germ cell tumor metastasis following platinum-based chemotherapy. BMC Urol. 2013;13:9.PubMedCentralCrossRefPubMed Zeh N, Wild PJ, Bode PK, Kristiansen G, Moch H, Sulser T, Hermanns T. Retroperitoneal teratoma with somatic malignant transformation: a papillary renal cell carcinoma in a testicular germ cell tumor metastasis following platinum-based chemotherapy. BMC Urol. 2013;13:9.PubMedCentralCrossRefPubMed
21.
Zurück zum Zitat Fung C, Fossa SD, Milano MT, Oldenburg J, Travis LB. Solid tumors after chemotherapy or surgery for testicular nonseminoma: a population-based study. J Clin Oncol. 2013;31(30):3807–14.PubMedCentralCrossRefPubMed Fung C, Fossa SD, Milano MT, Oldenburg J, Travis LB. Solid tumors after chemotherapy or surgery for testicular nonseminoma: a population-based study. J Clin Oncol. 2013;31(30):3807–14.PubMedCentralCrossRefPubMed
22.
Zurück zum Zitat Mesbahi O E, Terrier-Lacombe MJ, Rebischung C, Theodore C, Vanel D, Fizazi K. Chemotherapy in patients with teratoma with malignant transformation. Eur Urol. 2007;51(5):1306–11.CrossRefPubMed Mesbahi O E, Terrier-Lacombe MJ, Rebischung C, Theodore C, Vanel D, Fizazi K. Chemotherapy in patients with teratoma with malignant transformation. Eur Urol. 2007;51(5):1306–11.CrossRefPubMed
23.
Zurück zum Zitat Vaughn DJ, Hwang W, Lal P, Rosen MA, Gallagher M, O’Dwyer PJ. Phase 2 trial of the cyclin-dependent kinase 4/6 inhibitor palbociclib in patients with retinoblastoma protein-expressing germ cell tumors. Cancer. 2015;121(9):1463–8.CrossRefPubMed Vaughn DJ, Hwang W, Lal P, Rosen MA, Gallagher M, O’Dwyer PJ. Phase 2 trial of the cyclin-dependent kinase 4/6 inhibitor palbociclib in patients with retinoblastoma protein-expressing germ cell tumors. Cancer. 2015;121(9):1463–8.CrossRefPubMed
Metadaten
Titel
A 59-year-old patient with somatic type malignancy as a relapse of testicular tumor after 28 years
A patient with somatic type malignancy
verfasst von
Andreas Edwin Juarso, MD
Malte Kiehl, MD
Olaf Pfennig, MD
Günther Wittenberg, MD
Florian Weissinger, MD
Publikationsdatum
01.09.2015
Verlag
Springer Vienna
Erschienen in
memo - Magazine of European Medical Oncology / Ausgabe 3/2015
Print ISSN: 1865-5041
Elektronische ISSN: 1865-5076
DOI
https://doi.org/10.1007/s12254-015-0222-8

Weitere Artikel der Ausgabe 3/2015

memo - Magazine of European Medical Oncology 3/2015 Zur Ausgabe