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Erschienen in: Wiener klinische Wochenschrift 9-10/2015

01.05.2015 | original article

Patient’s behavior and attitudes toward the management of benign prostatic hyperplasia among patients with the risk of disease progression: prospective study by “Prostate and Expectations of Treatment Epidemiology Research (PETER) study group”

verfasst von: Peter Weibl, MD, Tobias Klatte, Peter Laurinc, Roman Tomaškin, Shahrokh F. Shariat, Miroslav Helbich, Danica Fackovcova, Peter Bujdák

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 9-10/2015

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Summary

Background

The aim of the study was to evaluate patients attitudes with benign prostatic hyperplasia at the risk of progression during a 12-month period of observation.

Materials and methods

A total of 426 patients from 45 outpatients centers were included and prospectively followed. Inclusion criteria were: age > 50 years, International Prostate Symptom Score (IPSS) > 8, prostate volume > 30 cm3 (transabdominal ultrasound) and PSA > 1.5 to < 10 ng/ml.

Results

In all, 28.6 % patients were naive, 62.9 % used monotherapy (alpha-blocker), and 8.5 % combined treatment (alpha-blocker/5alpha-reductase inhibitor/dutasteride). The most bothersome symptoms were the weak urine stream (60.8 %) and nocturia (59.2 %). Patients expectations from the treatment were stabilization of the disease and reducing the risk of surgery rather than rapid resolution of symptoms. Despite the presence of symptoms, 2.3 % patients claimed that benign prostatic hyperplasia/lower urinary tract symptoms had no impact on their quality of life (QoL), in 48.1 % only little impact on QoL, and 47.9 % patients percepted their symptoms as severe. Out of 71.4 % patients treated previously, 26.5 % patients were indecisive about the satisfaction of present treatment. Visual analog score was percepted more optimistically rather than the IPSS. Pearsonʼs correlation r = 0.68 at the beginning and r = 0.83 at the end of the study.

Conclusions

Prostate and Expectations of Treatment Epidemiology Research study highlights and reflects on patients behavior and self-perception, patients self-perception of the disease and therapeutic priorities during the 1 year of observation.
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Metadaten
Titel
Patient’s behavior and attitudes toward the management of benign prostatic hyperplasia among patients with the risk of disease progression: prospective study by “Prostate and Expectations of Treatment Epidemiology Research (PETER) study group”
verfasst von
Peter Weibl, MD
Tobias Klatte
Peter Laurinc
Roman Tomaškin
Shahrokh F. Shariat
Miroslav Helbich
Danica Fackovcova
Peter Bujdák
Publikationsdatum
01.05.2015
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 9-10/2015
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-014-0668-4

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